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Molecular phenotypes are important links between genomic information and organismic functions, fitness, and evolution. Complex phenotypes, which are also called quantitative traits, often depend on multiple genomic loci. Their evolution…

种群与进化 · 定量生物学 2015-06-12 Armita Nourmohammad , Stephan Schiffels , Michael Laessig

While modern physics and biology satisfactorily explain the passage from the Big Bang to the formation of Earth and the first cells to present-day life, respectively, the origins of biochemical life still remain an open question. Since…

种群与进化 · 定量生物学 2025-02-25 Praful Gagrani , David Baum

We present a simple physical model that recapitulates several features of biological evolution, while being based only on thermally-driven attachment and detachment of elementary building blocks. Through its dynamics, this model samples a…

种群与进化 · 定量生物学 2025-07-11 Guy Bunin , Olivier Rivoire

The genetic blueprint for the essential functions of life is encoded in DNA, which is translated into proteins -- the engines driving most of our metabolic processes. Recent advancements in genome sequencing have unveiled a vast diversity…

神经与进化计算 · 计算机科学 2024-06-12 James S. L. Browning , Daniel R. Tauritz , John Beckmann

We introduce a model of molecular evolution in which the fitness of an individual depends both on its own and on the parent's genotype. The model can be solved by means of a nonlinear mapping onto the standard quasispecies model. The…

生物物理 · 物理学 2009-11-07 Claus O. Wilke

Conventional population genetics considers the evolution of a limited number of genotypes corresponding to phenotypes with different fitness. As model phenotypes, in particular RNA secondary structure, have become computationally tractable,…

种群与进化 · 定量生物学 2008-04-22 Gergely J. Szollosi , Imre Derenyi

Emergence is a phenomenon taken for granted in science but also still not well understood. We have developed a model of artificial genetic evolution intended to allow for emergence on genetic, population and social levels. We present the…

种群与进化 · 定量生物学 2015-05-19 Chris Marriott , Jobran Chebib

Developmental trajectories are known to be canalized, or robust to both environmental and genetic perturbations. However, even when these trajectories are decanalized by an environmental perturbation outside of the range of conditions to…

生物物理 · 物理学 2025-09-25 Yuuki Matsushita , Archishman Raju

Genotype-to-phenotype mappings translate genotypic variations such as mutations into phenotypic changes. Neutrality is the observation that some mutations do not lead to phenotypic changes. Studying the search trajectories in genotypic and…

种群与进化 · 定量生物学 2023-06-26 Ting Hu , Gabriela Ochoa , Wolfgang Banzhaf

In this paper, we introduce a model of evolution and learning in robots that co-optimizes a distribution of latent design vectors (genotypes) and a mixture of control experts (neural modules), which are gated by the latent coordinates of…

机器人学 · 计算机科学 2026-05-26 Yibin Wang , Muhan Li , Zihan Guo , Sam Kriegman

Cellular automata have been useful artificial models for exploring how relatively simple rules combined with spatial memory can give rise to complex emergent patterns. Moreover, studying the dynamics of how rules emerge under artificial…

元胞自动机与格子气 · 物理学 2014-07-11 Theodore P. Pavlic , Alyssa M. Adams , Paul C. W. Davies , Sara Imari Walker

This short paper presents an abstract, tunable model of genomic structural change within the cell lifecycle and explores its use with simulated evolution. A well-known Boolean model of genetic regulatory networks is extended to include…

计算工程、金融与科学 · 计算机科学 2012-01-18 Larry Bull

This study facilitates the understanding of evolutionary transitions in individuality (ETIs) through a novel artificial life framework, named VitaNova, that intricately merges self-organization and natural selection to simulate the…

种群与进化 · 定量生物学 2024-09-23 Nam H. Le , Richard Watson , Mike Levin , Chrys Buckley

A theoretical and experimental analysis is made of the effects of self-adaptation in a simple evolving system. Specifically, we consider the effects of coding the mutation and crossover probabilities of a genetic algorithm evolving in…

adap-org · 物理学 2008-02-03 C. Stephens , I. Garcia , J. Mora , H. Waelbroeck

We investigate the evolutionary dynamics of an idealised model for the robust self-assembly of two-dimensional structures called polyominoes. The model includes rules that encode interactions between sets of square tiles that drive the…

种群与进化 · 定量生物学 2013-09-03 Iain G. Johnston , Sebastian A. Ahnert , Jonathan P. K. Doye , Ard A. Louis

The continuity of life and its evolution, we proposed, emerge from an interactive group process manifested in networks of interaction. We term this process \textit{survival-of-the-fitted}. Here, we reason that survival of the fitted results…

神经与进化计算 · 计算机科学 2025-06-17 Irun R. Cohen , Assaf Marron

The evolutionary process has been modelled in many ways using both stochastic and deterministic models. We develop an algebraic model of evolution in a population of asexually reproducing organisms in which we represent a stochastic walk in…

An object-oriented combinator chemistry was used to construct an artificial organism with a system architecture possessing characteristics necessary for organisms to evolve into more complex forms. This architecture supports modularity by…

神经与进化计算 · 计算机科学 2018-05-17 Lance R. Williams

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

种群与进化 · 定量生物学 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

Microbiological systems evolve to fulfill their tasks with maximal efficiency. The immune system is a remarkable example, where self-non self distinction is accomplished by means of molecular interaction between self proteins and antigens,…

细胞行为 · 定量生物学 2013-08-26 Marcio Argollo de Menezes , Edgardo Brigatti , Veit Schwämmle