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In Environmental Scanning Electron Microscopy (ESEM) experiments, the acquisition parameters are generally kept constant throughout the collection of a data set. This limits data collection to one data set at a time, and frequent human…

Various methods have been proposed to enhance image quality in ultrafast ultrasound. Coherent compounding can improve image quality using multiple steered diverging transmits when motion occurring between transmits is corrected for.…

We present a simple and efficient method for refining maps or correspondences by iterative upsampling in the spectral domain that can be implemented in a few lines of code. Our main observation is that high quality maps can be obtained even…

图形学 · 计算机科学 2019-09-13 Simone Melzi , Jing Ren , Emanuele Rodolà , Abhishek Sharma , Peter Wonka , Maks Ovsjanikov

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

定量方法 · 定量生物学 2023-05-01 Louise Budzynski , Andrea Pagnani

Spatial transcriptomics data analysis integrates cellular transcriptional activity with spatial coordinates to identify spatial domains, infer cell-type dynamics, and characterize gene expression patterns within tissues. Despite recent…

定量方法 · 定量生物学 2026-03-25 Sean Cottrell , Guo-Wei Wei , Longxiu Huang

We aim to automatize the identification of collective variables to simplify and speed up enhanced sampling simulations of conformational dynamics in biomolecules. We focus on anharmonic low-frequency vibrations that exhibit fluctuations on…

统计力学 · 物理学 2025-08-01 Souvik Mondal , Michael A. Sauer , Matthias Heyden

The theory behind compressive sampling pre-supposes that a given sequence of observations may be exactly represented by a linear combination of a small number of basis vectors. In practice, however, even small deviations from an exact…

最优化与控制 · 数学 2014-06-30 Jonathan M. Nichols , Albert K. Oh , Rebecca M. Willett

High-throughput chromatin conformation capture (Hi-C) data provide insights into the 3D structure of chromosomes, with normalization being a crucial pre-processing step. A common technique for normalization is matrix balancing, which…

应用统计 · 统计学 2025-06-17 John Park , Ning Hao , Yue Selena Niu , Ming Hu

Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared…

图像与视频处理 · 电气工程与系统科学 2025-03-06 Kai Pan , Linyang Li , Li Lin , Pujin Cheng , Junyan Lyu , Lei Xi , Xiaoyin Tang

Current state-of-the-art generative models map noise to data distributions by matching flows or scores. A key limitation of these models is their inability to readily integrate available partial observations and additional priors. In…

Incorrectly sized balloon catheters can lead to increased post-surgical complications, yet even with preoperative imaging, correct selection remains a challenge. With limited feedback during surgery, it is difficult to verify correct…

The objective of electrical impedance tomography (EIT) is to reconstruct the internal conductivity of a physical body based on current and voltage measurements at the boundary of the body. In many medical applications the exact shape of the…

最优化与控制 · 数学 2021-10-25 J. P. Agnelli , V. Kolehmainen , M. Lassas , P. Ola , S. Siltanen

Open gantry C-arm systems that are placed within the interventional room enable 3-D imaging and guidance for stroke therapy without patient transfer. This can profit in drastically reduced time-totherapy, however, due to the interventional…

This paper presents STrEAM (SuperTrace Evaluation Automated for Matching), a Mathematica package that calculates all functional supertraces which arise when matching a generic UV model onto a relativistic Effective Field Theory (EFT) at one…

高能物理 - 唯象学 · 物理学 2021-08-02 Timothy Cohen , Xiaochuan Lu , Zhengkang Zhang

Cryo-EM reconstruction algorithms seek to determine a molecule's 3D density map from a series of noisy, unlabeled 2D projection images captured with an electron microscope. Although reconstruction algorithms typically model the 3D volume as…

生物大分子 · 定量生物学 2021-07-06 Ellen D. Zhong , Adam Lerer , Joseph H. Davis , Bonnie Berger

Electron ptychography has seen a recent surge of interest for phase sensitive imaging at atomic or near-atomic resolution. However, applications are so far mainly limited to radiation-hard samples because the required doses are too high for…

Anatomical structures such as blood vessels in contrast-enhanced CT (ceCT) images can be challenging to segment due to the variability in contrast medium diffusion. The combined use of ceCT and contrast-free (CT) CT images can improve the…

图像与视频处理 · 电气工程与系统科学 2022-10-05 Giammarco La Barbera , Haithem Boussaid , Francesco Maso , Sabine Sarnacki , Laurence Rouet , Pietro Gori , Isabelle Bloch

In the past decade, deep conditional generative models have revolutionized the generation of realistic images, extending their application from entertainment to scientific domains. Single-particle cryo-electron microscopy (cryo-EM) is…

计算机视觉与模式识别 · 计算机科学 2024-10-01 Jiakai Zhang , Qihe Chen , Yan Zeng , Wenyuan Gao , Xuming He , Zhijie Liu , Jingyi Yu

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. Its unique ability to capture structural variability has spurred the development of heterogeneous…

计算机视觉与模式识别 · 计算机科学 2025-01-17 Minkyu Jeon , Rishwanth Raghu , Miro Astore , Geoffrey Woollard , Ryan Feathers , Alkin Kaz , Sonya M. Hanson , Pilar Cossio , Ellen D. Zhong

The paper explores the problem of \emph{spectral compressed sensing}, which aims to recover a spectrally sparse signal from a small random subset of its $n$ time domain samples. The signal of interest is assumed to be a superposition of $r$…

信息论 · 计算机科学 2015-01-05 Yuxin Chen , Yuejie Chi