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Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

图像与视频处理 · 电气工程与系统科学 2024-03-18 Antonio Curci , Andrea Esposito

The glioblastoma multiforme is the most common malignant primary brain tumor and is one of the highest malignant human neoplasms. During the course of disease, the evaluation of tumor volume is an essential part of the clinical follow-up.…

计算机视觉与模式识别 · 计算机科学 2011-03-10 Jan Egger , Miriam H. A. Bauer , Daniela Kuhnt , Barbara Carl , Christoph Kappus , Bernd Freisleben , Christopher Nimsky

Tumor segmentation in multimodal medical images has seen a growing trend towards deep learning based methods. Typically, studies dealing with this topic fuse multimodal image data to improve the tumor segmentation contour for a single…

图像与视频处理 · 电气工程与系统科学 2020-09-25 Theresa Neubauer , Maria Wimmer , Astrid Berg , David Major , Dimitrios Lenis , Thomas Beyer , Jelena Saponjski , Katja Bühler

Graph neural networks (GNNs) have emerged as powerful tools for learning protein structures by capturing spatial relationships at the residue level. However, existing GNN-based methods often face challenges in learning multiscale…

机器学习 · 计算机科学 2026-02-03 Shih-Hsin Wang , Yuhao Huang , Taos Transue , Justin Baker , Jonathan Forstater , Thomas Strohmer , Bao Wang

Patient-derived cells (PDC) mouse xenografts are increasingly important tools in glioblastoma (GBM) research, essential to investigate case-specific growth patterns and treatment responses. Despite the central role of xenograft models in…

定量方法 · 定量生物学 2024-03-15 Adam A. Malik , Cecilia Krona , Soumi Kundu , Philip Gerlee , Sven Nelander

Glioblastoma is the most common and aggressive malignant adult tumor of the central nervous system, with a grim prognosis and heterogeneous morphologic and molecular profiles. Since adopting the current standard-of-care treatment 18 years…

图像与视频处理 · 电气工程与系统科学 2023-05-16 Bhakti Baheti , Sunny Rai , Shubham Innani , Garv Mehdiratta , Sharath Chandra Guntuku , MacLean P. Nasrallah , Spyridon Bakas

Glioblastoma is a common brain malignancy that tends to occur in older adults and is almost always lethal. The effectiveness of chemotherapy, being the standard treatment for most cancer types, can be improved if a particular genetic…

图像与视频处理 · 电气工程与系统科学 2022-03-01 Numan Saeed , Shahad Hardan , Kudaibergen Abutalip , Mohammad Yaqub

Deep learning-based brain tumor segmentation (BTS) models for multi-modal MRI images have seen significant advancements in recent years. However, a common problem in practice is the unavailability of some modalities due to varying scanning…

计算机视觉与模式识别 · 计算机科学 2024-06-17 Weide Liu , Jingwen Hou , Xiaoyang Zhong , Huijing Zhan , Jun Cheng , Yuming Fang , Guanghui Yue

Recent years have seen a surge in research focused on leveraging graph learning techniques to detect neurodegenerative diseases. However, existing graph-based approaches typically lack the ability to localize and extract the specific brain…

计算机视觉与模式识别 · 计算机科学 2025-06-16 Nguyen Linh Dan Le , Jing Ren , Ciyuan Peng , Chengyao Xie , Bowen Li , Feng Xia

Cancers are characterized by remarkable heterogeneity and diverse prognosis. Accurate cancer classification is essential for patient stratification and clinical decision-making. Although digital pathology has been advancing cancer diagnosis…

计算机视觉与模式识别 · 计算机科学 2025-02-13 Xiaofei Wang , Hanyu Liu , Yupei Zhang , Boyang Zhao , Hao Duan , Wanming Hu , Yonggao Mou , Stephen Price , Chao Li

Graph self-supervised learning (GSSL) has demonstrated strong potential for generating expressive graph embeddings without the need for human annotations, making it particularly valuable in domains with high labeling costs such as molecular…

机器学习 · 计算机科学 2026-02-25 Jiele Wu , Haozhe Ma , Zhihan Guo , Thanh Vinh Vo , Tze Yun Leong

Predicting molecular properties with data-driven methods has drawn much attention in recent years. Particularly, Graph Neural Networks (GNNs) have demonstrated remarkable success in various molecular generation and prediction tasks. In…

定量方法 · 定量生物学 2021-10-19 Zaixi Zhang , Qi Liu , Hao Wang , Chengqiang Lu , Chee-Kong Lee

Physical models in the form of partial differential equations serve as important priors for many under-constrained problems. One such application is tumor treatment planning, which relies on accurately estimating the spatial distribution of…

Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

Glioblastoma Multiforme (GBM) is an aggressive form of malignant brain tumor with a generally poor prognosis. Treatment usually includes a mix of surgical resection, radiation therapy, and akylating chemotherapy but, even with these…

医学物理 · 物理学 2024-01-11 Erich Schmitz , Yunhui Guo , Jing Wang

It is imperative that breast cancer is detected precisely and timely to improve patient outcomes. Diagnostic methodologies have traditionally relied on unimodal approaches; however, medical data analytics is integrating diverse data sources…

机器学习 · 计算机科学 2024-06-21 Faseela Abdullakutty , Younes Akbari , Somaya Al-Maadeed , Ahmed Bouridane , Rifat Hamoudi

Tumor heterogeneity is a challenge to designing effective and targeted therapies. Glioma-type identification depends on specific molecular and histological features, which are defined by the official WHO classification CNS. These guidelines…

应用统计 · 统计学 2023-05-23 Roberta Coletti , Mónica L. Mendonça , Susana Vinga , Marta B. Lopes

Surgery for gliomas (intrinsic brain tumors), especially when low-grade, is challenging due to the infiltrative nature of the lesion. Currently, no real-time, intra-operative, label-free and wide-field tool is available to assist and guide…

So far, fingerprinting studies have focused on identifying features from single-modality MRI data, which capture individual characteristics in terms of brain structure, function, or white matter microstructure. However, due to the lack of a…

计算机视觉与模式识别 · 计算机科学 2017-09-20 Kuldeep Kumar , Laurent Chauvin , Mathew Toews , Olivier Colliot , Christian Desrosiers

The RSNA-MICCAI brain tumor radiogenomic classification challenge aimed to predict MGMT biomarker status in glioblastoma through binary classification on Multi parameter mpMRI scans: T1w, T1wCE, T2w and FLAIR. The dataset is splitted into…

图像与视频处理 · 电气工程与系统科学 2024-01-19 Amr Mohamed , Mahmoud Rabea , Aya Sameh , Ehab Kamal