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This article proposes a systematic methodological review and objective criticism of existing methods enabling the derivation of time-varying Granger-causality statistics in neuroscience. The increasing interest and the huge number of…

应用统计 · 统计学 2017-04-12 Sezen Cekic , Didier Grandjean , Olivier Renaud

Large case/control Genome-Wide Association Studies (GWAS) often include groups of related individuals with known relationships. When testing for associations at a given locus, current methods incorporate only the familial relationships…

应用统计 · 统计学 2014-08-01 Joshua N. Sampson , Bill Wheeler , Peng Li , Jianxin Shi

We study Ising models for describing data and show that autoregressive methods may be used to learn their connections, also in the case of asymmetric connections and for multi-spin interactions. For each link the linear Granger causality is…

神经元与认知 · 定量生物学 2015-05-18 Mario Pellicoro , Sebastiano Stramaglia

Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially…

Inspired by Jang et al. (2022), we propose a Granger causality-in-the-mean test for bivariate $k-$Markov stationary processes based on a recently introduced class of non-linear models, i.e., vine copula models. By means of a simulation…

计量经济学 · 经济学 2025-05-08 Roberto Fuentes-Martínez , Irene Crimaldi , Armando Rungi

Although deep learning techniques show promising results for many neuroimaging tasks in research settings, they have not yet found widespread use in clinical scenarios. One of the reasons for this problem is that many machine learning…

图像与视频处理 · 电气工程与系统科学 2024-12-05 Vibujithan Vigneshwaran , Erik Ohara , Matthias Wilms , Nils Forkert

Identifying ``true causality'' is a fundamental challenge in complex systems research. Widely adopted methods, like the Granger causality test, capture statistical dependencies between variables rather than genuine driver-response…

最优化与控制 · 数学 2025-05-05 Yingzhu Liu , Shengyuan Huang , Zhongkui Li , Xiaoguang Yang , Wenjun Mei

The literature manifests that schizophrenia is associated with alterations in brain network connectivity. We investigate whether large-scale Extended Granger Causality (lsXGC) can capture such alterations using resting-state fMRI data. Our…

神经元与认知 · 定量生物学 2021-01-27 Axel Wismüller , M. Ali Vosoughi

Latent confounding has been a long-standing obstacle for causal reasoning from observational data. One popular approach is to model the data using acyclic directed mixed graphs (ADMGs), which describe ancestral relations between variables…

机器学习 · 计算机科学 2023-03-23 Matthew Ashman , Chao Ma , Agrin Hilmkil , Joel Jennings , Cheng Zhang

Granger causality is a statistical notion of causal influence based on prediction via vector autoregression. Developed originally in the field of econometrics, it has since found application in a broader arena, particularly in neuroscience.…

数学物理 · 物理学 2015-05-14 Lionel Barnett , Adam B Barrett , Anil K. Seth

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, structural brain changes, and genetic predispositions. This study leverages machine-learning and statistical techniques to investigate…

应用统计 · 统计学 2025-10-29 Riddhik Basu , Arkaprava Roy

Gait analysis, an expanding research area, employs non invasive sensors and machine learning techniques for a range of applicatio ns. In this study, we concentrate on gait analysis for detecting cognitive decline in Parkinson's disease (PD)…

信号处理 · 电气工程与系统科学 2023-06-13 Abdullah Alharthi

Identifying causal relations among simultaneously acquired signals is an important problem in multivariate time series analysis. For linear stochastic systems Granger proposed a simple procedure called the Granger causality to detect such…

混沌动力学 · 物理学 2009-11-10 Yonghong Chen , Govindan Rangarajan , Jianfeng Feng , Mingzhou Ding

This paper considers joint learning of multiple sparse Granger graphical models to discover underlying common and differential Granger causality (GC) structures across multiple time series. This can be applied to drawing group-level brain…

机器学习 · 计算机科学 2021-05-25 Parinthorn Manomaisaowapak , Jitkomut Songsiri

This paper proposes a new approach for testing Granger non-causality on panel data. Instead of aggregating panel member statistics, we aggregate their corresponding p-values and show that the resulting p-value approximately bounds the type…

统计方法学 · 统计学 2022-02-24 Lenon Minorics , Caner Turkmen , David Kernert , Patrick Bloebaum , Laurent Callot , Dominik Janzing

We introduce a new approach to functional causal modeling from observational data, called Causal Generative Neural Networks (CGNN). CGNN leverages the power of neural networks to learn a generative model of the joint distribution of the…

This paper presents Gem, a model-agnostic approach for providing interpretable explanations for any GNNs on various graph learning tasks. Specifically, we formulate the problem of providing explanations for the decisions of GNNs as a causal…

机器学习 · 计算机科学 2021-06-08 Wanyu Lin , Hao Lan , Baochun Li

Common psychiatric and brain disorders are highly heritable and affected by a number of genetic risk factors, yet the mechanism by which these genetic factors contribute to the disorders through alterations in brain structure and function…

统计方法学 · 统计学 2025-11-26 Neng Wang , Eric V. Slud , Tianzhou Ma

Integrated Gradients (IG) is a widely used attribution method in explainable AI, particularly in computer vision applications where reliable feature attribution is essential. A key limitation of IG is its sensitivity to the choice of…

机器学习 · 统计学 2025-11-21 Kien Tran Duc Tuan , Tam Nguyen Trong , Son Nguyen Hoang , Khoat Than , Anh Nguyen Duc

Identifying directed interactions between species from time series of their population densities has many uses in ecology. This key statistical task is equivalent to causal time series inference, which connects to the Granger causality (GC)…

种群与进化 · 定量生物学 2020-11-10 Frederic Barraquand , Coralie Picoche , Matteo Detto , Florian Hartig