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This paper aims to conduct a comprehensive theoretical analysis of current diffusion models. We introduce a novel generative learning methodology utilizing the Schr{\"o}dinger bridge diffusion model in latent space as the framework for…

机器学习 · 统计学 2024-12-24 Yuling Jiao , Lican Kang , Huazhen Lin , Jin Liu , Heng Zuo

Low-dimensional descriptions of neural network dynamics are an effective tool for bridging different scales of organization of brain structure and function. Recent advances in deriving mean-field descriptions for networks of coupled…

神经元与认知 · 定量生物学 2021-11-03 Richard Gast , Thomas R. Knösche , Helmut Schmidt

Foundation models have demonstrated remarkable performance across modalities such as language and vision. However, model reuse across distinct modalities (e.g., text and vision) remains limited due to the difficulty of aligning internal…

机器学习 · 计算机科学 2025-05-20 Ali Gholamzadeh , Noor Sajid

Schr\"{o}dinger bridge is a diffusion process that steers a given distribution to another in a prescribed time while minimizing the effort to do so. It can be seen as the stochastic dynamical version of the optimal mass transport, and has…

最优化与控制 · 数学 2024-10-29 Alexis M. H. Teter , Wenqing Wang , Abhishek Halder

For an arbitrary Hilbert space-valued Ornstein-Uhlenbeck process we construct the Ornstein-Uhlenbeck Bridge connecting a starting point $x$ and an endpoint $y$ that belongs to a certain linear subspace of full measure. We derive also a…

概率论 · 数学 2007-05-23 Beniamin Goldys , Bohdan Maslowski

Efficient and accurate brain ventricle segmentation from clinical CT scans is critical for emergency surgeries like ventriculostomy. With the challenges in poor soft tissue contrast and a scarcity of well-annotated databases for clinical…

图像与视频处理 · 电气工程与系统科学 2024-07-16 Reihaneh Teimouri , Marta Kersten-Oertel , Yiming Xiao

We solve the Schr\"odinger equation from first principles to investigate the many-body effects in the expansion dynamics of one-dimensional repulsively interacting bosons released from a harmonic trap. We utilize the multiconfigurational…

量子气体 · 物理学 2024-03-04 Rhombik Roy , Barnali Chakrabarti , Arnaldo Gammal

We derive an exact solution of an explicitly time-dependent multichannel model of quantum mechanical nonadiabatic transitions. Our model corresponds to the case of a single linear diabatic energy level interacting with a band of an…

量子物理 · 物理学 2017-02-27 J Lin , N A Sinitsyn

The advent of single-cell multi-omics technologies has enabled the simultaneous profiling of diverse omics layers within individual cells. Integrating such multimodal data provides unprecedented insights into cellular identity, regulatory…

细胞行为 · 定量生物学 2025-06-27 Zhen Yuan , Shaoqing Jiao , Yihang Xiao , Jiajie Peng

In a previous study we developed a mean-field theory of dynamical transitions for the totally-asymmetric simple-exclusion process (TASEP) with open boundaries and Langmuir kinetics, in the so-called balanced regime, characterized by equal…

统计力学 · 物理学 2020-08-11 D. Botto , A. Pelizzola , M. Pretti , M. Zamparo

The development of powerful numerical techniques has drastically improved our understanding of quantum matter out of equilibrium. Inspired by recent progress in the area of noisy intermediate-scale quantum devices, this paper highlights…

量子物理 · 物理学 2024-04-01 Jonas Richter

We provide a general framework for learning diffusion bridges that transport prior to target distributions. It includes existing diffusion models for generative modeling, but also underdamped versions with degenerate diffusion matrices,…

机器学习 · 计算机科学 2025-08-14 Denis Blessing , Julius Berner , Lorenz Richter , Gerhard Neumann

Unsupervised learning requiring only raw data is not only a fundamental function of the cerebral cortex, but also a foundation for a next generation of artificial neural networks. However, a unified theoretical framework to treat sensory…

机器学习 · 统计学 2020-09-09 Haiping Huang

Reconstructing high-fidelity fluid dynamics from sparse temporal observations is quite challenging, mainly due to the chaotic and non-linear nature of fluid transport. Standard deep learning-based interpolation methods often tend to regress…

流体动力学 · 物理学 2026-04-28 Eshwar R. A. , Nevin Mathew Thomas , Nehal G , Farida M. Begam

We propose a novel method for simulating conditioned diffusion processes (diffusion bridges) in Euclidean spaces. By training a neural network to approximate bridge dynamics, our approach eliminates the need for computationally intensive…

机器学习 · 统计学 2025-06-23 Gefan Yang , Frank van der Meulen , Stefan Sommer

The phase field model can accurately simulate the evolution of microstructures with complex morphologies, and it has been widely used for cell modeling in the last two decades. However, compared to other cellular models such as the…

生物物理 · 物理学 2022-06-13 Xiangyu Kuang , Guoye Guan , Chao Tang , Lei Zhang

Biological foundation models have shown strong performance in single-cell representation learning by applying transformer architectures directly to gene-expression matrices. However, these approaches predominantly operate in static settings…

机器学习 · 计算机科学 2026-05-28 Manuel Dileo , Andrea Sottoriva

The momentum Schr\"odinger Bridge (mSB) has emerged as a leading method for accelerating generative diffusion processes and reducing transport costs. However, the lack of simulation-free properties inevitably results in high training costs…

机器学习 · 统计学 2025-01-29 Kevin Rojas , Yixin Tan , Molei Tao , Yuriy Nevmyvaka , Wei Deng

Distinguishing active from passive dynamics is a fundamental challenge in understanding the motion of living cells and other active matter systems. Here, we introduce a framework that combines physical modeling, analytical theory, and…

Diffusion and Schr\"{o}dinger Bridge models have established state-of-the-art performance in generative modeling but are often hampered by significant computational costs and complex training procedures. While continuous-time bridges…

机器学习 · 计算机科学 2025-12-16 Maria Khilchuk , Vladimir Latypov , Pavel Kleshchev , Alexander Hvatov