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Comparing the survival times among two groups is a common problem in time-to-event analysis, for example if one would like to understand whether one medical treatment is superior to another. In the standard survival analysis setting, there…

统计方法学 · 统计学 2023-07-07 Dennis Dobler , Eni Musta

A very classical problem in statistics is to test the stochastic superiority of one distribution to another. However, many existing approaches are developed for independent samples and, moreover, do not take censored data into account. We…

统计方法学 · 统计学 2023-06-19 Dennis Dobler , Kathrin Möllenhoff

In biomedical studies, paired survival data arise naturally when two event times are observed within the same subject. Existing statistical models seldom accommodate both cure fractions and complex dependence structures. In this paper, we…

统计方法学 · 统计学 2026-04-28 Masaki Hino , Shogo Kato , Takeshi Emura

We propose a class of dimension reduction methods for right censored survival data using a counting process representation of the failure process. Semiparametric estimating equations are constructed to estimate the dimension reduction…

统计方法学 · 统计学 2018-06-11 Qiang Sun , Ruoqing Zhu , Tao Wang , Donglin Zeng

For semi-supervised techniques to be applied safely in practice we at least want methods to outperform their supervised counterparts. We study this question for classification using the well-known quadratic surrogate loss function. Using a…

机器学习 · 统计学 2016-02-26 Jesse H. Krijthe , Marco Loog

We propose a novel approach for estimating mean survival time in the presence of censored data, in which we divide the population under study into survival-ordered fractions defined by a set of proportions, and compute the mean survival…

统计方法学 · 统计学 2018-10-18 Celia García-Pareja , Matteo Bottai

Existing survival analysis techniques heavily rely on strong modelling assumptions and are, therefore, prone to model misspecification errors. In this paper, we develop an inferential method based on ideas from conformal prediction, which…

统计方法学 · 统计学 2023-04-25 Emmanuel J. Candès , Lihua Lei , Zhimei Ren

A case-control family study is a study where individuals with a disease of interest (case probands) and individuals without the disease (control probands) are randomly sampled from a well-defined population. Possibly right-censored age at…

统计方法学 · 统计学 2018-12-04 David M. Zucker , Malka Gorfine

Multi-regional clinical trials (MRCTs) play an increasingly crucial role in global pharmaceutical development by expediting data gathering and regulatory approval across diverse patient populations. However, differences in recruitment…

统计方法学 · 统计学 2024-04-15 Kaiyuan Hua , Hwanhee Hong , Xiaofei Wang

The cause of failure in cohort studies that involve competing risks is frequently incompletely observed. To address this, several methods have been proposed for the semiparametric proportional cause-specific hazards model under a missing at…

统计方法学 · 统计学 2020-02-24 Giorgos Bakoyannis , Ying Zhang , Constantin T. Yiannoutsos

An important research topic in survival analysis is related to the modeling and estimation of the cure rate, i.e. the proportion of subjects that will never experience the event of interest. However, most estimation methods proposed so far…

统计方法学 · 统计学 2018-04-06 Mikael Escobar-Bach , Ingrid Van Keilegom

Survival time prediction from medical images is important for treatment planning, where accurate estimations can improve healthcare quality. One issue affecting the training of survival models is censored data. Most of the current survival…

计算机视觉与模式识别 · 计算机科学 2022-05-27 Renato Hermoza , Gabriel Maicas , Jacinto C. Nascimento , Gustavo Carneiro

Item nonresponse is frequently encountered in practice. Ignoring missing data can lose efficiency and lead to misleading inference. Fractional imputation is a frequentist approach of imputation for handling missing data. However, the…

统计方法学 · 统计学 2018-09-18 Hejian Sang , Jae Kwang Kim

We propose a general index model for survival data, which generalizes many commonly used semiparametric survival models and belongs to the framework of dimension reduction. Using a combination of geometric approach in semiparametrics and…

统计理论 · 数学 2017-10-17 Ge Zhao , Yanyuan Ma , Wenbin Lu

Stepped wedge cluster randomized trials (SW-CRTs) with binary outcomes are increasingly used in prevention and implementation studies. Marginal models represent a flexible tool for analyzing SW-CRTs with population-averaged interpretations,…

统计方法学 · 统计学 2021-01-05 Fan Li , Hengshi Yu , Paul J. Rathouz , Elizabeth L. Turner , John S. Preisser

We introduce a generalized promotion time cure model motivated by a new biological consideration. The new approach is flexible to model heterogeneous survival data, in particular for addressing intra-sample heterogeneity. We also indicate…

统计方法学 · 统计学 2025-02-19 Zhi Zhao , Fatih Kızılaslan

We propose a new class of semiparametric regression models of mean residual life for censored outcome data. The models, which enable us to estimate the expected remaining survival time and generalize commonly used mean residual life models,…

统计理论 · 数学 2020-11-10 Ge Zhao , Yanyuan Ma , Huazhen Lin , Yi Li

We develop a multivariate cure survival model to estimate lifetime patterns of colorectal cancer screening. Screening data cover long periods of time, with sparse observations for each person. Some events may occur before the study begins…

统计方法学 · 统计学 2015-09-16 Yolanda Hagar , Danielle Harvey , Laurel Beckett

Analysis of survival data with biased samples caused by left-truncation or length-biased sampling has received extensive interest. Many inference methods have been developed for various survival models. These methods, however, break down…

统计理论 · 数学 2018-12-31 Li-Pang Chen

The proportional hazards assumption in the commonly used Cox model for censored failure time data is often violated in scientific studies. Yang and Prentice (2005) proposed a novel semiparametric two-sample model that includes the…

统计方法学 · 统计学 2012-06-06 Guoqing Diao , Donglin Zeng , Song Yang