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Magnetic particle imaging (MPI) is an in-vivo imaging method to detect magnetic nanoparticles for blood vessel imaging and molecular target imaging. Compared with conventional molecular imaging devices (such as nuclear medicine imaging PET…

医学物理 · 物理学 2024-04-26 Guang Jia , Zhongwei Bian , Tianshu Li , Shi Bai , Chenxing Hu , Lixuan Zhao , Peng Gao , Tanping Li , Hui Hui , Jie Tian

We propose a novel stimulated emission depletion (STED) microscopy based on array detection and photon reassignment. By replacing the single-point detector in traditional STED with a detector array and utilizing the photon reassignment…

Magnetic particle imaging (MPI) is a tracer-based imaging modality that detects superparamagnetic iron oxide nanoparticles in vivo, with applications in cancer cell tracking, lymph node mapping, and cell therapy monitoring. We introduce a…

Magnetic Particle Imaging (MPI) is a promising noninvasive in vivo imaging modality that makes it possible to map the spatial distribution of superparamagnetic nanoparticles by exposing them to dynamic magnetic fields. In the Field-Free…

数值分析 · 数学 2025-08-08 Vladyslav Gapyak , Thomas März , Andreas Weinmann

With recent developments in microscopy, such as stimulated emission depletion (STED) microscopy, far-field imaging at resolutions better than the diffraction limit is now a commercially available technique. Here, we show that, in the…

光学 · 物理学 2012-05-29 Chris J. Lee , Klaus J. Boller

Stimulated Emission Depletion (STED) microscopy has emerged as a powerful technique providing visualization of biological structures at the molecular level in living samples. In this technique, the diffraction limit is broken by selectively…

Magnetic Particle Imaging (MPI) is an emerging imaging modality that maps the spatial distribution of magnetic nanoparticles. The x-space reconstruction in MPI results in highly blurry images, where the resolution depends on both system…

Magnetic Particle Imaging (MPI) is a highly sensitive imaging method that enables the visualization of magnetic tracer materials with a temporal resolution of more than 46 volumes per second. In MPI the size of the field of view scales with…

Magnetic particle imaging is a promising medical imaging technique. Applying changing magnetic fields to tracer material injected into the object under investigation results in a change in magnetization. Measurement of related induced…

图像与视频处理 · 电气工程与系统科学 2023-06-21 Stephanie Blanke , Christina Brandt

The purpose of this study was to present image reconstruction methods for magnetic particle imaging (MPI) with a field-free-line (FFL) encoding scheme and to propose the use of the maximum likelihood-expectation maximization (ML-EM)…

医学物理 · 物理学 2016-06-13 Kenya Murase

Magnetic Particle Imaging (MPI) is a promising tracer-based, functional medical imaging technique which measures the non-linear magnetization response of magnetic nanoparticles to a dynamic magnetic field. For image reconstruction, system…

图像与视频处理 · 电气工程与系统科学 2021-08-26 Christina Brandt , Christiane Schmidt

We derive a new 3D model for magnetic particle imaging (MPI) that is able to incorporate realistic magnetic fields in the reconstruction process. In real MPI scanners, the generated magnetic fields have distortions that lead to deformed…

数值分析 · 数学 2020-12-30 Gaël Bringout , Wolfgang Erb , Jürgen Frikel

Magnetic particle imaging (MPI) is a tomographic method to determine the spatio-temporal distribution of magnetic nanoparticles. In this document, a file format for the standardized storage of MPI and magnetic particle spectroscopy (MPS)…

Magnetic Particle Imaging (MPI) is an emerging medical imaging modality that is not yet adopted by clinical practice. Most of the working MPI prototypes including commercial-grade research MPI scanners utilize cylindrical bores that limit…

医学物理 · 物理学 2017-07-13 Alexey Tonyushkin

Fluorescence depletion microscopy techniques such as STED and RESOLFT require optical fields with a well-defined and spatially confined central intensity minimum to achieve sub-diffraction lateral resolution. Here, we present the design and…

Magnetic particle imaging (MPI) is an imaging method that can visualize magnetic nanoparticles in positive contrast, without radiation exposure. Recently, we proposed an image reconstruction method for projection-based MPI (pMPI), in which…

医学物理 · 物理学 2023-05-01 Kenya Murase

In this work, we propose a structured illumination (SI) method based on a two-photon excitation (TPE) scanning laser beam. Advantages of TPE methods include optical sectioning, low photo-toxicity, and robustness in the face of sample…

生物物理 · 物理学 2016-09-16 Alex Bardales , Qinggele Li , Bingzhao Zhu , Xiaodong Tao , Marc Reinig , Joel Kubby

Magnetoencephalography (MEG) allows the non-invasive detection of interictal epileptiform discharges (IEDs). Clinical MEG analysis in epileptic patients traditionally relies on the visual identification of IEDs, which is time consuming and…

Magnetic Particle Imaging (MPI) is an emerging medical imaging modality that images the spatial distribution of superparamagnetic iron oxide (SPIO) nanoparticles using their nonlinear response to applied magnetic fields. In standard x-space…

医学物理 · 物理学 2019-12-11 Semih Kurt , Yavuz Muslu , Emine Ulku Saritas

Magnetic Particle Imaging (MPI) is a tomographic imaging technique for determining the spatial distribution of superparamagnetic nanoparticles. Current MPI systems are capable of imaging iron masses over a wide dynamic range of more than…

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