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The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Kilian Hett , Vinh-Thong Ta , José V. Manjón , Pierrick Coupé

Overlapping Speech Detection (OSD) aims to identify regions where multiple speakers overlap in a conversation, a critical challenge in multi-party speech processing. This work proposes a speaker-aware progressive OSD model that leverages a…

声音 · 计算机科学 2025-05-30 Zhaokai Sun , Li Zhang , Qing Wang , Pan Zhou , Lei Xie

Alzheimer's disease is one of the diseases that mostly affects older people without being a part of aging. The most common symptoms include problems with communicating and abstract thinking, as well as disorientation. It is important to…

图像与视频处理 · 电气工程与系统科学 2020-12-01 Fatih Altay , Guillermo Ramon Sanchez , Yanli James , Stephen V. Faraone , Senem Velipasalar , Asif Salekin

Receiver operating characteristic (ROC) curves are used ubiquitously to evaluate covariates, markers, or features as potential predictors in binary problems. We distinguish raw ROC diagnostics and ROC curves, elucidate the special role of…

统计方法学 · 统计学 2018-09-14 Tilmann Gneiting , Peter Vogel

Early diagnosis and discovery of therapeutic drug targets are crucial objectives for effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely…

机器学习 · 计算机科学 2026-05-01 Maryam Khalid , Fadeel Sher Khan , John Broussard , Arko Barman

Estimating average human performance has been performed inconsistently in research in diagnostic medicine. This has been particularly apparent in the field of medical artificial intelligence, where humans are often compared against AI…

统计方法学 · 统计学 2020-09-28 Luke Oakden-Rayner , Lyle Palmer

The area under a receiver operating characteristic curve (AUC) is a useful tool to assess the performance of continuous-scale diagnostic tests on binary classification. In this article, we propose an empirical likelihood (EL) method to…

统计方法学 · 统计学 2022-05-05 Chul Moon , Xinlei Wang , Johan Lim

Receiver-operating-characteristic (ROC) analysis was used to assess the suitability of various heart rate variability (HRV) measures for correctly classifying electrocardiogram records of varying lengths as normal or revealing the presence…

医学物理 · 物理学 2019-10-23 Stefan Thurner , Markus C. Feurstein , Steven B. Lowen , Malvin C. Teich

In high-stakes risk prediction, quantifying uncertainty through interval-valued predictions is essential for reliable decision-making. However, standard evaluation tools like the receiver operating characteristic (ROC) curve and the area…

机器学习 · 计算机科学 2026-02-05 Yuqi Li , Matthew M. Engelhard

Open Set Recognition (OSR) extends image classification to an open-world setting, by simultaneously classifying known classes and identifying unknown ones. While conventional OSR approaches can detect Out-of-Distribution (OOD) samples, they…

计算机视觉与模式识别 · 计算机科学 2022-08-16 Piyapat Saranrittichai , Chaithanya Kumar Mummadi , Claudia Blaiotta , Mauricio Munoz , Volker Fischer

Accurate prediction of clinical scores is critical for early detection and prognosis of Alzheimers disease (AD). While existing approaches primarily focus on forecasting the ADAS-Cog global score, they often overlook the predictive value of…

Receiver Operating Characteristic (ROC) curves are plots of true positive rate versus false positive rate which are used to evaluate binary classification algorithms. Because the Area Under the Curve (AUC) is a constant function of the…

机器学习 · 计算机科学 2023-02-23 Kyle R. Rust , Toby D. Hocking

The Receiver Operating Characteristic (ROC) curve of a binary classifier has often been utilized to measure the performance of the classifier. The area beneath this curve is used in particular because of its quoted probabilistic…

机器学习 · 计算机科学 2026-05-05 Steven Redolfi

We develop three efficient approaches for generating visual explanations from 3D convolutional neural networks (3D-CNNs) for Alzheimer's disease classification. One approach conducts sensitivity analysis on hierarchical 3D image…

计算机视觉与模式识别 · 计算机科学 2018-07-09 Chengliang Yang , Anand Rangarajan , Sanjay Ranka

Receiver operating characteristic (ROC) analysis is one of the most popular approaches for evaluating and comparing the accuracy of medical diagnostic tests. Although various methodologies have been developed for estimating ROC curves and…

统计方法学 · 统计学 2022-08-16 Ainesh Sewak , Torsten Hothorn

The revolutionary developments in the field of supervised machine learning have paved way to the development of CAD tools for assisting doctors in diagnosis. Recently, the former has been employed in the prediction of neurological disorders…

计算机视觉与模式识别 · 计算机科学 2017-06-27 Jerrin Thomas Panachakel , Jeena R. S.

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

神经元与认知 · 定量生物学 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

A three-dimensional convolutional neural network was developed to classify T1-weighted brain MRI scans as healthy or Alzheimer. The network comprises 3D convolution, pooling, batch normalization, dense ReLU layers, and a sigmoid output.…

图像与视频处理 · 电气工程与系统科学 2025-06-18 Thien Nhan Vo , Bac Nam Ho

Magnetic Resonance Imaging (MRI) plays a pivotal role in the early diagnosis and monitoring of Alzheimer's disease (AD). However, the subtle structural variations in brain MRI scans often pose challenges for conventional deep learning…

图像与视频处理 · 电气工程与系统科学 2025-12-22 Faisal Ahmed

Identification of brain regions related to the specific neurological disorders are of great importance for biomarker and diagnostic studies. In this paper, we propose an interpretable Graph Convolutional Network (GCN) framework for the…

机器学习 · 计算机科学 2022-04-29 Houliang Zhou , Lifang He , Yu Zhang , Li Shen , Brian Chen