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In clinical trials with recurrent events, such as repeated hospitalizations terminating with death, it is important to consider the patient events overall history for a thorough assessment of treatment effects. The occurrence of fewer…

统计方法学 · 统计学 2025-09-08 Alessandra Ragni , Torben Martinussen , Thomas Scheike

Progressive multi-state survival outcomes are common in trials with recurrent or sequential events and require treatment effect estimands that remain interpretable without proportional intensity or Markov assumptions. The restricted mean…

统计方法学 · 统计学 2026-01-22 Xi Fang , Bingkai Wang , Guangyu Tong , Liangyuan Hu , Shuangge Ma , Fan Li

While well-established methods for time-to-event data are available when the proportional hazards assumption holds, there is no consensus on the best inferential approach under non-proportional hazards (NPH). However, a wide range of…

This paper considers the practically important case of nonparametrically estimating heterogeneous average treatment effects that vary with a limited number of discrete and continuous covariates in a selection-on-observables framework where…

计量经济学 · 经济学 2019-08-26 Michael Zimmert , Michael Lechner

In recent years, censored quantile regression has enjoyed an increasing popularity for survival analysis while many existing works rely on linearity assumptions. In this work, we propose a Global Censored Quantile Random Forest (GCQRF) for…

机器学习 · 统计学 2024-10-17 Siyu Zhou , Limin Peng

Nonparametric random coefficient (RC)-density estimation has mostly been considered in the marginal density case under strict independence of RCs and covariates. This paper deals with the estimation of RC-densities conditional on a…

计量经济学 · 经济学 2022-01-21 Stephan Martin

This paper focuses on quantifying and estimating the predictive accuracy of prognostic models for time-to-event outcomes with competing events. We consider the time-dependent discrimination and calibration metrics, including the receiver…

统计方法学 · 统计学 2017-07-14 Cai Wu , Liang Li

In interval censored models with current status observations, the variables are indicators of the presence of individuals on observation intervals and covariates. When several individuals share the same observation interval, a simple…

统计理论 · 数学 2007-10-10 Odile Pons

Dynamic Treatment Regimes (DTRs) provide a systematic framework for optimizing sequential decision-making in chronic disease management, where therapies must adapt to patients' evolving clinical profiles. Inverse probability weighting (IPW)…

统计方法学 · 统计学 2026-03-26 Chloe Si , David A. Stephens , Erica E. M. Moodie

In this work, nonparametric statistical inference is provided for the continuous-time M/G/1 queueing model from a Bayesian point of view. The inference is based on observations of the inter-arrival and service times. Beside other…

统计理论 · 数学 2017-03-22 Cornelia Wichelhaus , Moritz von Rohrscheidt

A novel estimation approach for a general class of semi-parametric multivariate time series models is introduced where the conditional mean is modeled through parametric functions. The focus of the estimation is the conditional mean…

统计方法学 · 统计学 2025-07-21 Mirko Armillotta

This work develops a flexible inferential framework for nonparametric causal inference in time-to-event settings, based on stochastic interventions defined through multiplicative scaling of the intensity governing an intermediate event…

统计方法学 · 统计学 2026-02-04 Helene Charlotte Wiese Rytgaard , Mark van der Laan

Since survival data occur over time, often important covariates that we wish to consider also change over time. Such covariates are referred as time-dependent covariates. Quantile regression offers flexible modeling of survival data by…

统计方法学 · 统计学 2014-05-01 Malka Gorfine , Yair Goldberg , Yaacov Ritov

The Brier score is commonly used for evaluating probability predictions. In survival analysis, with right-censored observations of the event times, this score can be weighted by the inverse probability of censoring (IPCW) to retain its…

机器学习 · 统计学 2019-12-19 Håvard Kvamme , Ørnulf Borgan

Progressive censoring scheme has received considerable attention in recent years. In this paper we introduce a new type-II progressive censoring scheme for two samples. It is observed that the proposed censoring scheme is analytically more…

统计方法学 · 统计学 2016-09-20 Shuvashree Mondal , Debasis Kundu

Interval-censoring frequently occurs in studies of chronic diseases where disease status is inferred from intermittently collected biomarkers. Although many methods have been developed to analyze such data, they typically assume perfect…

统计方法学 · 统计学 2026-05-26 Yuhao Deng , Donglin Zeng , Yuanjia Wang

We revisit the classical causal inference problem of estimating the average treatment effect in the presence of fully observed confounding variables using two-stage semiparametric methods. In existing theoretical studies of methods such as…

统计方法学 · 统计学 2022-05-23 Steve Yadlowsky

This study extends the Bayesian nonparametric instrumental variable regression model to determine the structural effects of covariates on the conditional quantile of the response variable. The error distribution is nonparametrically…

统计方法学 · 统计学 2016-08-30 Genya Kobayashi , Kota Ogasawara

We propose consistent nonparametric tests of conditional independence for time series data. Our methods are motivated from the difference between joint conditional cumulative distribution function (CDF) and the product of conditional CDFs.…

计量经济学 · 经济学 2021-10-12 Xiaojun Song , Haoyu Wei

We develop an estimation methodology for a factor model for high-dimensional matrix-valued time series, where common stochastic trends and common stationary factors can be present. We study, in particular, the estimation of (row and column)…

统计方法学 · 统计学 2025-01-06 Rong Chen , Simone Giannerini , Greta Goracci , Lorenzo Trapani