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Reconstructing the tree of life from molecular sequences is a fundamental problem in computational biology. Modern data sets often contain a large number of genes, which can complicate the reconstruction problem due to the fact that…

概率论 · 数学 2017-07-21 Constantinos Daskalakis , Sebastien Roch

Rooted acyclic graphs appear naturally when the phylogenetic relationship of a set $X$ of taxa involves not only speciations but also recombination, horizontal transfer, or hybridization, that cannot be captured by trees. A variety of…

种群与进化 · 定量生物学 2022-04-29 Marc Hellmuth , David Schaller , Peter F. Stadler

Phylogenomics is a new field which applies to tools in phylogenetics to genome data. Due to a new technology and increasing amount of data, we face new challenges to analyze them over a space of phylogenetic trees. Because a space of…

组合数学 · 数学 2020-05-15 Ruriko Yoshida

It was recently observed by de Vienne et al. that a simple square root transformation of distances between taxa on a phylogenetic tree allowed for an embedding of the taxa into Euclidean space. While the justification for this was based on…

种群与进化 · 定量生物学 2016-05-04 Mark Layer , John A. Rhodes

Here we introduce researchers in algebraic biology to the exciting new field of cophylogenetics. Cophylogenetics is the study of concomitantly evolving organisms (or genes), such as host and parasite species. Thus the natural objects of…

种群与进化 · 定量生物学 2009-02-03 Peter Huggins , Megan Owen , Ruriko Yoshida

A method for creating a forest of model trees to fit samples of a function defined on images is described in several steps: down-sampling the images, determining a tree's hyperplanes, applying convolutions to the hyperplanes to handle small…

机器学习 · 计算机科学 2026-01-28 William Ward Armstrong , Hongyi Li , Jun Xu

Reticulate evolutionary processes result in phylogenetic histories that cannot be modeled using a tree topology. Here, we apply methods from topological data analysis to molecular sequence data with reticulations. Using a simple example, we…

定量方法 · 定量生物学 2015-11-05 Kevin Emmett , Raul Rabadan

We study the role of phylogenetic trees on correlations in mutation processes. Generally, correlations decay exponentially with the generation number. We find that two distinct regimes of behavior exist. For mutation rates smaller than a…

统计力学 · 物理学 2009-10-31 E. Ben-Naim , A. S. Lapedes

Gene gain-loss-duplication models are commonly based on continuous-time birth-death processes. Employed in a phylogenetic context, such models have been increasingly popular in studies of gene content evolution across multiple genomes.…

种群与进化 · 定量生物学 2021-07-27 Miklos Csuros

Understanding the dynamics of genome rearrangements is a major issue of phylogenetics. Phylogenetics is the study of species evolution. A major goal of the field is to establish evolutionary relationships within groups of species, in order…

数据结构与算法 · 计算机科学 2014-10-22 Antoine Thomas

Evolutionary relationships between species are usually inferred through phylogenetic analysis, which provides phylogenetic trees computed from allelic profiles built by sequencing specific regions of the sequences and abstracting them to…

数据结构与算法 · 计算机科学 2021-01-01 Luana Silva

Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of non-treelike evolutionary events, like recombination, hybridization, or lateral gene transfer. In a recent series of papers devoted to the…

种群与进化 · 定量生物学 2007-07-17 Gabriel Cardona , Francesc Rossello , Gabriel Valiente

Phylogenetic trees are widely used to understand the evolutionary history of organisms. Tree shapes provide information about macroevolutionary processes. However, macroevolutionary models are unreliable for inferring the true processes…

种群与进化 · 定量生物学 2021-10-11 Albert Ch. Soewongsono , Barbara R. Holland , Małgorzata M. O'Reilly

Most of major algorithms for phylogenetic tree reconstruction assume that sequences in the analyzed set either do not have any offspring, or that parent sequences can maximally mutate into just two descendants. The graph resulting from such…

种群与进化 · 定量生物学 2013-10-09 Piotr Plonski , Jan P. Radomski

Phylogenetic networks are rooted acyclic directed graphs in which the leaves are identified with members of a set X of species. The cluster of a vertex is the set of leaves that are descendants of the vertex. A network is "distinct-cluster"…

组合数学 · 数学 2017-04-11 Stephen J. Willson

Recently, so-called treebased phylogenetic networks have gained considerable interest in the literature, where a treebased network is a network that can be constructed from a phylogenetic tree, called the base tree, by adding additional…

种群与进化 · 定量生物学 2019-11-28 Mareike Fischer , Michelle Galla , Lina Herbst , Yangjing Long , Kristina Wicke

Recently, much attention has been given to understanding recombination events along a chromosome in a variety of field. For instance, many population genetics problems are limited by the inaccuracy of inferred evolutionary histories of…

定量方法 · 定量生物学 2017-10-31 Jacqueline Kane , Joseph Rusinko , Katherine Thompson

Large scale databases are available that contain homologous gene families constructed from hundreds of complete genome sequences from across the three domains of Life. Here we discuss approches of increasing complexity aimed at extracting…

基因组学 · 定量生物学 2011-02-14 Gergely J Szöllősi , Vincent Daubin

Tree Containment is a fundamental problem in phylogenetics useful for verifying a proposed phylogenetic network, representing the evolutionary history of certain species. Tree Containment asks whether the given phylogenetic tree (for…

种群与进化 · 定量生物学 2024-06-14 Arkadiy Dushatskiy , Esther Julien , Leen Stougie , Leo van Iersel

We consider the problem of estimating the evolutionary history of a set of species (phylogeny or species tree) from several genes. It is known that the evolutionary history of individual genes (gene trees) might be topologically distinct…

种群与进化 · 定量生物学 2016-11-18 Gautam Dasarathy , Robert Nowak , Sebastien Roch