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相关论文: Biomedical Knowledge Graph: A Survey of Domains, T…

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Biomedical knowledge graphs (KGs) are widely used across research and translational settings, yet their design decisions and implementation are often opaque. Unlike ontologies that more frequently adhere to established creation principles,…

This comprehensive review aims to provide an overview of the current state of Healthcare Knowledge Graphs (HKGs), including their construction, utilization models, and applications across various healthcare and biomedical research domains.…

Knowledge graphs are powerful tools for representing and organising complex biomedical data. Several knowledge graph embedding algorithms have been proposed to learn from and complete knowledge graphs. However, a recent study demonstrates…

Knowledge Graphs (KGs) have made a qualitative leap and effected a real revolution in knowledge representation. This is leveraged by the underlying structure of the KG which underpins a better comprehension, reasoning and interpretation of…

数据库 · 计算机科学 2021-03-04 Bilal Abu-Salih

Knowledge Graph Completion has been increasingly adopted as a useful method for helping address several tasks in biomedical research, such as drug repurposing or drug-target identification. To that end, a variety of datasets and Knowledge…

The term life sciences refers to the disciplines that study living organisms and life processes, and include chemistry, biology, medicine, and a range of other related disciplines. Research efforts in life sciences are heavily data-driven,…

The incorporation of data analytics in the healthcare industry has made significant progress, driven by the demand for efficient and effective big data analytics solutions. Knowledge graphs (KGs) have proven utility in this arena and are…

Within clinical, biomedical, and translational science, an increasing number of projects are adopting graphs for knowledge representation. Graph-based data models elucidate the interconnectedness between core biomedical concepts, enable…

Drug discovery and development is a complex and costly process. Machine learning approaches are being investigated to help improve the effectiveness and speed of multiple stages of the drug discovery pipeline. Of these, those that use…

Biomedical knowledge graphs (KGs) hold rich information on entities such as diseases, drugs, and genes. Predicting missing links in these graphs can boost many important applications, such as drug design and repurposing. Recent work has…

计算与语言 · 计算机科学 2021-09-22 Rahul Nadkarni , David Wadden , Iz Beltagy , Noah A. Smith , Hannaneh Hajishirzi , Tom Hope

Patient-Centric Knowledge Graphs (PCKGs) represent an important shift in healthcare that focuses on individualized patient care by mapping the patient's health information in a holistic and multi-dimensional way. PCKGs integrate various…

Knowledge-based biomedical data science (KBDS) involves the design and implementation of computer systems that act as if they knew about biomedicine. Such systems depend on formally represented knowledge in computer systems, often in the…

人工智能 · 计算机科学 2022-09-13 Tiffany J. Callahan , Harrison Pielke-Lombardo , Ignacio J. Tripodi , Lawrence E. Hunter

Knowledge graphs (KGs) are gaining prominence in Healthcare AI, especially in drug discovery and pharmaceutical research as they provide a structured way to integrate diverse information sources, enhancing AI system interpretability. This…

人工智能 · 计算机科学 2023-09-29 Satvik Garg , Shivam Parikh , Somya Garg

Knowledge graphs (KGs) have emerged as a powerful framework for representing and integrating complex biomedical information. However, assembling KGs from diverse sources remains a significant challenge in several aspects, including entity…

机器学习 · 计算机科学 2023-10-10 Yijia Xiao , Dylan Steinecke , Alexander Russell Pelletier , Yushi Bai , Peipei Ping , Wei Wang

Information extraction and data mining in biochemical literature is a daunting task that demands resource-intensive computation and appropriate means to scale knowledge ingestion. Being able to leverage this immense source of technical…

Papers, patents, and clinical trials are essential scientific resources in biomedicine, crucial for knowledge sharing and dissemination. However, these documents are often stored in disparate databases with varying management standards and…

数字图书馆 · 计算机科学 2025-06-19 Jian Xu , Chao Yu , Jiawei Xu , Vetle I. Torvik , Jaewoo Kang , Mujeen Sung , Min Song , Yi Bu , Ying Ding

With the rapid development of biomedical software and hardware, a large amount of relational data interlinking genes, proteins, chemical components, drugs, diseases, and symptoms has been collected for modern biomedical research. Many…

人工智能 · 计算机科学 2021-01-21 Yankai Chen , Yaozu Wu , Shicheng Ma , Irwin King

Knowledge graphs (KGs) are important products of the semantic web, which are widely used in various application domains. Healthcare is one of such domains where KGs are intensively used, due to the high requirement for knowledge accuracy…

人工智能 · 计算机科学 2025-07-31 Yuzhang Xie , Xu Han , Ran Xu , Xiao Hu , Jiaying Lu , Carl Yang

Knowledge graphs, collectively as a knowledge network, have become critical tools for knowledge discovery in computable and explainable knowledge systems. Due to the semantic and structural complexities of biomedical data, these knowledge…

其他定量生物学 · 定量生物学 2025-09-29 Chunlei Wu , Hongfang Liu , Jason Flannick , Mark A. Musen , Andrew I. Su , Lawrence Hunter , Thomas M. Powers , Cathy H. Wu

This paper describes an ongoing multi-scale visual analytics approach for exploring and analyzing biomedical knowledge at scale.We utilize global and local views, hierarchical and flow-based graph layouts, multi-faceted search, neighborhood…

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