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Collective cell migration plays a crucial role in many developmental processes that underlie morphogenesis, wound healing, or cancer progression. In such coordinated behaviours, cells are organised in coherent structures and actively…

软凝聚态物质 · 物理学 2021-06-16 Carolina Trenado , Luis L. Bonilla , Alejandro Martínez-Calvo

Knowledge about existence, strength, and dominant direction of causal influences is of paramount importance for understanding complex systems. With limited amounts of realistic data, however, current methods for investigating causal links…

数据分析、统计与概率 · 物理学 2020-10-20 Erik Laminski , Klaus R. Pawelzik

A piecewise continuous map for modeling bursting and spiking behaviour of isolated neuron is proposed. The map was created from phenomenological viewpoint. The map demonstrates oscillations, which are qualitatively similar to oscillations…

混沌动力学 · 物理学 2007-05-23 K. V. Andreev , L. V. Krasichkov

This paper focuses on analysis and design of time-varying complex networks having fractional order dynamics. These systems are key in modeling the complex dynamical processes arising in several natural and man made systems. Notably,…

信号处理 · 电气工程与系统科学 2018-09-17 Gaurav Gupta , Sergio Pequito , Paul Bogdan

This topic review communicates working experiences regarding interaction of a multiplicity of processes. Our experiences come from climate change modelling, materials science, cell physiology and public health, and macroeconomic modelling.…

综合经济学 · 经济学 2020-02-07 Bernhelm Booss-Bavnbek , Rasmus Kristoffer Pedersen , Ulf Rørbæk Pedersen

Simulation models are an absolute necessity in the human and social sciences, which can only very exceptionally use experimental science methods to construct their knowledge. Models enable the simulation of social processes by replacing the…

计算机与社会 · 计算机科学 2020-01-06 J. Raimbault , D. Pumain

We introduce a model for describing the dynamics of large numbers of interacting cells. The fundamental dynamical variables in the model are sub-cellular elements, which interact with each other through phenomenological intra- and…

定量方法 · 定量生物学 2007-05-23 T. J. Newman

Swarming or collective motion of living entities is one of the most common and spectacular manifestations of living systems having been extensively studied in recent years. A number of general principles have been established. The…

细胞行为 · 定量生物学 2014-06-06 Elod Mehes , Tamas Vicsek

Emotions are a central key for understanding human beings and of fundamental importance regarding their impact in human and animal behaviors. They have been for a long time a subject of study for various scholars including in particular…

神经元与认知 · 定量生物学 2021-12-15 B. Ambrosio

In many body systems, constituents interact with each other, forming a recursive pattern of mutual interaction and giving rise to many interesting phenomena. Based upon concepts of the modern many body theory, a model for a generic many…

软凝聚态物质 · 物理学 2007-05-23 Zhen Ye

From interacting cellular components to networks of neurons and neural systems, interconnected units comprise a fundamental organizing principle of the nervous system. Understanding how their patterns of connections and interactions give…

神经元与认知 · 定量生物学 2018-08-01 Danielle S. Bassett , Perry Zurn , Joshua I. Gold

Coordinated motion of cell monolayers during epithelial wound healing and tissue morphogenesis involves mechanical stress generation. Here we propose a model for the dynamics of epithelial expansion that couples mechanical deformations in…

软凝聚态物质 · 物理学 2015-06-09 Shiladitya Banerjee , Kazage J. C. Utuje , M. Cristina Marchetti

We present initial results regarding the existence, stability and interaction of linear and nonlinear vibrational modes in a system of two coupled, one dimensional lattices with unequal numbers of masses. The effects on these nonlinear…

生物物理 · 物理学 2007-05-23 Kyle Forinash

We derived here in a systematic way, and for a large class of scaling regimes, asymptotic models for the propagation of internal waves at the interface between two layers of immiscible fluids of different densities, under the rigid lid…

偏微分方程分析 · 数学 2007-12-27 Jerry L. Bona , David Lannes , Jean-Claude Saut

The study of dynamical systems defined on complex networks provides a natural framework with which to investigate myriad features of neural dynamics, and has been widely undertaken. Typically, however, networks employed in theoretical…

神经元与认知 · 定量生物学 2013-02-22 Reuben O'Dea , Jonathan J. Crofts , Marcus Kaiser

Due to the complexity of the human body, most diseases present a high inter-personal variability in the way they manifest, i.e. in their phenotype, which has important clinical repercussions - as for instance the difficulty in defining…

物理与社会 · 物理学 2018-06-06 Massimiliano Zanin , Juan Manuel Tuñas , Ernestina Menasalvas

What can we learn from the collective dynamics of a complex network about its interaction topology? Taking the perspective from nonlinear dynamics, we briefly review recent progress on how to infer structural connectivity (direct…

适应与自组织系统 · 物理学 2014-08-14 Marc Timme , Jose Casadiego

Physics perfectly describes neuronal operation, provided that we take into account that biology uses slow, positively charged ions rather than electrons as charge carriers and remove untested ad hoc hypotheses that contradict science's…

生物物理 · 物理学 2026-04-13 János Végh

A continuum model of epithelial tissue mechanics was formulated using cellular-level mechanical ingredients and cell morphogenetic processes, including cellular shape changes and cellular rearrangements. This model can include finite…

组织与器官 · 定量生物学 2017-09-06 Shuji Ishihara , Philippe Marcq , Kaoru Sugimura

Physics-based simulation of mesh based domains remains a challenging task. State-of-the-art techniques can produce realistic results but require expert knowledge. A major bottleneck in many approaches is the step of integrating a potential…

图形学 · 计算机科学 2023-11-07 Oshri Halimi , Egor Larionov , Zohar Barzelay , Philipp Herholz , Tuur Stuyck