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Empirical studies of graphs have contributed enormously to our understanding of complex systems. Known today as network science, what was originally a theoretical study of graphs has grown into a more scientific exploration of communities…

定量方法 · 定量生物学 2020-01-01 Ryan E. Langendorf , Debra S. Goldberg

How the very first nervous systems evolved remains a fundamental open question. Molecular and genomic techniques have revolutionized our knowledge of the molecular ingredients behind this transition but not yet provided a clear picture of…

神经元与认知 · 定量生物学 2017-10-31 Ronald A. J. van Elburg , Oltman O. de Wiljes , Michael Biehl , Fred A. Keijzer

Trophic coherence, a measure of the extent to which the nodes of a directed network are organised in levels, has recently been shown to be closely related to many structural and dynamical aspects of complex systems, including graph…

物理与社会 · 物理学 2016-07-22 Janis Klaise , Samuel Johnson

We develop an efficient package for the simulation of nuclear magnetic resonance spin echo experiments to study the effects of strong electronic spin correlations on the dynamics of the nuclear spin ensemble. A mean-field model is used to…

强关联电子 · 物理学 2026-02-09 Charles Snider , Stephen Carr , D. E. Feldman , Chandrasekhar Ramanathan , V. F. Mitrović

This essay is presented with two principal objectives in mind: first, to document the prevalence of fractals at all levels of the nervous system, giving credence to the notion of their functional relevance; and second, to draw attention to…

神经元与认知 · 定量生物学 2010-04-09 Gerhard Werner

The study of the interplay between the structure and dynamics of complex multilevel systems is a pressing challenge nowadays. In this paper, we use a semi-annealed approximation to study the stability properties of Random Boolean Networks…

物理与社会 · 物理学 2012-10-31 Emanuele Cozzo , Alex Arenas , Yamir Moreno

Network models are widely used to represent relational information among interacting units and the structural implications of these relations. Recently, social network studies have focused a great deal of attention on random graph models of…

应用统计 · 统计学 2010-10-06 Mark S. Handcock , Krista J. Gile

The human neuromuscular system consisting of skeletal muscles and neural circuits is a complex system that is not yet fully understood. Surface electromyography (EMG) can be used to study muscle behavior from the outside. Computer…

分布式、并行与集群计算 · 计算机科学 2021-07-16 Benjamin Maier

With the completion of human genome mapping, the focus of scientists seeking to explain the biological complexity of living systems is shifting from analyzing the individual components (such as a particular gene or biochemical reaction) to…

分子网络 · 定量生物学 2010-01-28 Sitabhra Sinha , T Jesan , Nivedita Chatterjee

Graph neural networks (GNNs) have demonstrated significant promise in modelling relational data and have been widely applied in various fields of interest. The key mechanism behind GNNs is the so-called message passing where information is…

机器学习 · 计算机科学 2023-10-31 Andi Han , Dai Shi , Lequan Lin , Junbin Gao

We introduce a framework to intertwine dynamical processes of different nature, each with its own distinct network topology, using a multilayer network approach. As an example of collective phenomena emerging from the interactions of…

适应与自组织系统 · 物理学 2017-04-05 Vincenzo Nicosia , Per Sebastian Skardal , Alex Arenas , Vito Latora

During the last decade, possibilities to realize new phenomena and create new applications by varying system properties in time have gained increasing attention in many research fields, spanning a wide range from acoustics to optics. While…

经典物理 · 物理学 2022-11-24 G. Ptitcyn , M. S. Mirmoosa , A. Sotoodehfar , S. A. Tretyakov

Despite great progress in neuroscience, there are still fundamental unanswered questions about the brain, including the origin of subjective experience and consciousness. Some answers might rely on new physical mechanisms. Given that…

生物物理 · 物理学 2021-04-19 Parisa Zarkeshian , Sourabh Kumar , Jack Tuszynski , Paul Barclay , Christoph Simon

Biomedical signals carry signature rhythms of complex physiological processes that control our daily bodily activity. The properties of these rhythms indicate the nature of interaction dynamics among physiological processes that maintain a…

机器学习 · 计算机科学 2020-12-14 Yassin Khalifa , Danilo Mandic , Ervin Sejdić

Biochemical signalling cascades transduce extracellular stimuli into cellular responses through sequences of discrete, node-to-node activations. While signal fidelity depends critically on local interaction kinetics, the mechanisms…

动力系统 · 数学 2026-04-20 Chathranee Jayathilaka , Mark B. Flegg

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

生物物理 · 物理学 2022-07-13 T. N. Azevedo , L. G. Rizzi

Understanding the operation of biological and artificial networks remains a difficult and important challenge. To identify general principles, researchers are increasingly interested in surveying large collections of networks that are…

机器学习 · 统计学 2022-01-14 Alex H. Williams , Erin Kunz , Simon Kornblith , Scott W. Linderman

We present a novel mathematical approach to model noise in dynamical systems. We do so by considering dynamics of a chain of diffusively coupled Nagumo cells affected by noise. We show that the noise in transmembrane current can be…

动力系统 · 数学 2011-05-13 A. A. Samoletov , B. N. Vasiev

Biological membranes and vesicles play a central role in living systems, forming dynamic interfaces that regulate cellular organization and function. Classical descriptions of membrane mechanics that are rooted in equilibrium statistical…

软凝聚态物质 · 物理学 2026-02-24 Sreekanth Ramesh , Prashant K. Purohit , Yashashree Kulkarni

Membrane tubulation is a ubiquitous process that occurs both at the plasma membrane and on the membranes of intracellular organelles. These tubulation events are known to be mediated by forces applied on the membrane either due to motor…

软凝聚态物质 · 物理学 2020-12-03 Arijit Mahapatra , Can Uysalel , Padmini Rangamani