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Indirect comparisons of treatment-specific outcomes across separate studies often inform decision-making in the absence of head-to-head randomized comparisons. Differences in baseline characteristics between study populations may introduce…

应用统计 · 统计学 2020-04-09 David Cheng , Rajeev Ayyagari , James Signorovitch

Assessing the synergistic high-order behaviors (HOBs) that emerge from underlying structural mechanisms is crucial to characterize complex systems. This work leverages the combined use of predictability and information measures to detect…

Quantum Computing (QC) offers outstanding potential for molecular characterization and drug discovery, particularly in solving complex properties like the Ground State Energy (GSE) of biomolecules. However, QC faces challenges due to…

化学物理 · 物理学 2024-12-17 Laia Coronas Sala , Parfait Atchade-Adelemou

We propose a framework for testing the homogeneity of conditional average treatment effects (CATEs) across multiple experimental and observational studies. Our approach leverages multiple randomized trials to assess whether treatment…

计量经济学 · 经济学 2026-02-25 Ana Armendariz , Martin Huber

Quantum error correction (QEC) is essential for realizing fault-tolerant quantum computation. Current QEC controllers execute all scheduled syndrome (parity-bit) measurement rounds before decoding, even when early syndrome data indicates…

量子物理 · 物理学 2026-02-20 Sanidhay Bhambay , Prakash Murali , Neil Walton , Thirupathaiah Vasantam

Recent stochastic gradient methods that have appeared in the literature base their efficiency and global convergence properties on a suitable control of the variance of the gradient batch estimate. This control is typically achieved by…

最优化与控制 · 数学 2025-06-11 Marco Boresta , Alberto De Santis , Stefano Lucidi

To better understand the spatial structure of large panels of economic and financial time series and provide a guideline for constructing semiparametric models, this paper first considers estimating a large spatial covariance matrix of the…

机器学习 · 统计学 2015-03-19 Song Song

This paper studies the use of highly stratified designs for the efficient estimation of a large class of treatment effect parameters that arise in the analysis of experiments. By a "highly stratified" design, we mean experiments in which…

计量经济学 · 经济学 2026-03-30 Yuehao Bai , Jizhou Liu , Azeem M. Shaikh , Max Tabord-Meehan

Conditional average treatment effects (CATEs) allow us to understand the effect heterogeneity across a large population of individuals. However, typical CATE learners assume all confounding variables are measured in order for the CATE to be…

机器学习 · 计算机科学 2022-02-01 Yao Zhang , Jeroen Berrevoets , Mihaela van der Schaar

In many scientific and engineering domains, physical experiments are often costly, non-replicable, or time-consuming. The Kennedy and O'Hagan (KOH) model framework has become a widely used approach for combining simulator runs with limited…

统计计算 · 统计学 2026-03-18 Hao Zhu , Markus Hainy

We introduce a mixture model for censored durations (C-mix), and develop maximum likelihood inference for the joint estimation of the time distributions and latent regression parameters of the model. We consider a high-dimensional setting,…

机器学习 · 统计学 2017-11-28 Simon Bussy , Agathe Guilloux , Stéphane Gaïffas , Anne-Sophie Jannot

Count outcomes in longitudinal studies are frequent in clinical and engineering studies. In frequentist and Bayesian statistical analysis, methods such as Mixed linear models allow the variability or correlation within individuals to be…

统计方法学 · 统计学 2024-07-15 Alejandra Estefanía Patiño Hoyos , Johnatan Cardona Jiménez

Approximate Bayesian Computation is widely used in systems biology for inferring parameters in stochastic gene regulatory network models. Its performance hinges critically on the ability to summarize high-dimensional system responses such…

机器学习 · 统计学 2021-04-13 Mattias Åkesson , Prashant Singh , Fredrik Wrede , Andreas Hellander

As data collections become larger, exploratory regression analysis becomes more important but more challenging. When observations are hierarchically clustered the problem is even more challenging because model selection with mixed effect…

机器学习 · 统计学 2017-02-15 Patrick J. Miller , Daniel B. McArtor , Gitta H. Lubke

Inferring the heterogeneous treatment effect is a fundamental problem in the sciences and commercial applications. In this paper, we focus on estimating Conditional Average Treatment Effect (CATE), that is, the difference in the conditional…

统计方法学 · 统计学 2021-03-23 Haomiao Meng , Xingye Qiao

For sparse high-dimensional regression problems, Cox and Battey [1, 9] emphasised the need for confidence sets of models: an enumeration of those small sets of variables that fit the data equivalently well in a suitable statistical sense.…

统计方法学 · 统计学 2025-06-10 R. M. Lewis , H. S. Battey

Utility-scale quantum computers require quantum error correcting codes with large numbers of physical qubits to achieve sufficiently low logical error rates. The performance of quantum error correction (QEC) is generally predicted through…

Motivated by a neuroscience application we study the problem of statistical estimation of a high-dimensional covariance matrix with a block structure. The block model embeds a structural assumption: the population of items (neurons) can be…

统计方法学 · 统计学 2025-03-03 Yunran Chen , Surya T Tokdar , Jennifer M Groh

This paper considers testing linear hypotheses of a set of mean vectors with unequal covariance matrices in large dimensional setting. The problem of testing the hypothesis $H_0 : \sum_{i=1}^q \beta_i \bmu_i =\bmu_0 $ for a given vector…

统计方法学 · 统计学 2015-12-22 Dandan Jiang

This paper considers distributed M-estimation under heterogeneous distributions among distributed data blocks. A weighted distributed estimator is proposed to improve the efficiency of the standard "Split-And-Conquer" (SaC) estimator for…

统计理论 · 数学 2022-09-15 Jia Gu , Songxi Chen