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Spatio-temporal signals arising from event-driven biological processes, such as surface electromyography (sEMG), exhibit asynchronous and highly structured activation patterns that are challenging to model using conventional discrete or…

机器学习 · 计算机科学 2026-05-05 Magnus Bengtsson

Weakly Supervised Semantic Segmentation (WSSS) is a challenging task aiming to learn the segmentation labels from class-level labels. In the literature, exploiting the information obtained from Class Activation Maps (CAMs) is widely used…

计算机视觉与模式识别 · 计算机科学 2022-11-24 Cenk Bircanoglu , Nafiz Arica

Many essential cellular functions depend on the viscoelastic properties of the cytoplasm. While techniques such as optical tweezers and atomic force microscopy can measure these properties, their reliance on localized probes prevents…

The dynamic architecture of the microtubule cytoskeleton is crucial for cell division, motility and morphogenesis. The dynamic properties of microtubules - growth, shrinkage, nucleation and severing - are regulated by an arsenal of…

定量方法 · 定量生物学 2021-07-06 Yin-wei Kuo , Jonathon Howard

We use photothermal induced resonance (PTIR) imaging and spectroscopy, in resonant and non-resonant mode, to study the cytoplasmic membrane and surface of intact cells. Non-resonant PTIR images apparently provide rich details of the cell…

应用物理 · 物理学 2021-01-27 Luca Quaroni

Real-space mapping of doping concentration in semiconductor devices is of great importance for the microelectronic industry. In this work, a scanning microwave impedance microscope (MIM) is employed to resolve the local conductivity…

介观与纳米尺度物理 · 物理学 2013-01-08 Worasom Kundhikanjana , Yongliang Yang , Qiaochu Tang , Kun Zhang Keji Lai , Yue Ma , Mike Kelly , Xinxin Li , Zhi-Xun Shen

Coherent spin resonance techniques, such as nuclear and electron spin resonance spectroscopy, have revolutionized non-invasive imaging by providing spectrally resolved information about spin dynamics. Motivated by the recent emergence of…

量子物理 · 物理学 2026-02-25 Santiago Beltrán-Romero , Stefan Löffler , Dennis Rätzel , Philipp Haslinger

Microcavities supporting Whispering-gallery modes (WGMs) are of great significance for on-chip optical information processing, which is frequently analyzed using ray dynamics that conventionally involves straight light trajectories in flat…

Whispering gallery mode (WGM) laser sensors, utilizing the interaction between the in-plane evanescent field and the surface vicinity, provide enhanced sensitivity in label-free sensing for bioanalysis and disease screening. However, the…

光学 · 物理学 2025-08-25 Xiaolu Cui , Jiyang Ma , Hao Wu , Shuoying Zhao , Xubiao Peng , Chuyu Li , Ruiqi Ming , Qing Zhao

Exosomes are significant facilitators of inter-cellular communication that can unveil cell-cell interactions, signaling pathways, regulatory mechanisms and disease diagnostics. Nonetheless, current analysis required large amount of data for…

生物大分子 · 定量生物学 2024-01-29 Yang Li , Xiaoming Lyu , Kuo Zhan , Haoyu Ji , Lei Qin , JianAn Huang

This study investigates the dynamics of red blood cells (RBCs) under the influence of evanescent waves generated by total internal reflection (TIR). Using a 1064 nm laser system and a dual-chamber prism setup, we quantified the mobility of…

We propose SERUM: an intriguingly simple yet highly effective method for marking images generated by diffusion models (DMs). We only add a unique watermark noise to the initial diffusion generation noise and train a lightweight detector to…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Jan Kociszewski , Hubert Jastrzębski , Tymoteusz Stępkowski , Filip Manijak , Krzysztof Rojek , Franziska Boenisch , Adam Dziedzic

Wearable sensing technology capable of point-of-care, continuous and non-invasive analysis of exosomes in biofluid such as tears and sweat is an essential part for future personalized medicine. Major detection and identification methods of…

介观与纳米尺度物理 · 物理学 2026-05-26 Yang Li , Xiaoming Lyu , Ling Xia , Kuo Zhan , Haoyu Ji , Lei Qin , Seppo J. Vainio , Jian-An Huang

The dynamics of photo-excited charge carriers, particularly their transport and interactions with defects and interfaces, play an essential role in determining the performance of a wide range of solar and optoelectronic devices. A thorough…

材料科学 · 物理学 2017-08-07 Bolin Liao , Ebrahim Najafi

Label-free nonlinear optical microscopy has become a powerful tool for biomedical research. However, the possible photodamage risk hinder further clinical applications. To reduce these adverse effects, we constructed a new platform of…

光学 · 物理学 2022-10-26 Geng Wang , Stephen A. Boppart , Haohua Tu

Accurate design of labelled oligo probes for the detection of miRNA biomarkers by Surface Enhanced Raman Scattering (SERS) may improve the exploitation of the plasmonic enhancement. This work, thus, critically investigates the role of probe…

Single-cell RNA sequencing (scRNA-seq), especially temporally resolved datasets, enables genome-wide profiling of gene expression dynamics at single-cell resolution across discrete time points. However, current technologies provide only…

基因组学 · 定量生物学 2025-11-19 Yue Ling , Peiqi Zhang , Zhenyi Zhang , Peijie Zhou

Surface electromyography (sEMG) is a non-invasive method of measuring neuromuscular potentials generated when the brain instructs the body to perform both fine and coarse locomotion. This technique has seen extensive investigation over the…

人机交互 · 计算机科学 2021-04-06 Mingde Zheng , Michael S. Crouch , Michael S. Eggleston

Label-free biosensors, including conventional quartz-crystal-microbalance (QCM) biosensor, are seriously affected by nonspecific adsorption of contaminants involved in analyte solution, and it is exceptionally difficult to extract the…

生物物理 · 物理学 2021-12-15 Kentaro Noi , Arihiro Iwata , Fumihito Kato , Hirotsugu Ogi

Neural networks possess incredible capabilities for extracting abstract features from data. Electromagnetic computing harnesses wave propagation to execute computational operations. Metasurfaces, composed of subwavelength meta-atoms, are…

信息论 · 计算机科学 2026-01-23 Jiancheng An , Chau Yuen , Marco Di Renzo , Mehdi Bennis , Merouane Debbah , Lajos Hanzo
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