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The mutual intensity and its equivalent phase-space representations quantify an optical field's state of coherence and are important tools in the study of light propagation and dynamics, but they can only be estimated indirectly from…

光学 · 物理学 2017-11-16 Chenglong Bao , George Barbastathis , Hui Ji , Zuowei Shen , Zhengyun Zhang

Detection of minimal residual disease (MRD) in cancer patients after surgery can provide an early marker for disease recurrence and guide subsequent treatment decisions. Accurate and sensitive estimation of tumour burden after cancer…

From the viewpoint of inverse problem, the optimization of drug release based on the multi-laminated drug controlled release devices has been regarded as the solution problem of the diffusion equation initial value inverse problem. In view…

数值分析 · 数学 2019-04-15 Xinming Zhang , Ling Ma

We consider the inverse problem of the reconstruction of the spatially distributed dielectric constant $\varepsilon_{r}\left(\mathbf{x}\right), \ \mathbf{x}\in \mathbb{R}^{3}$, which is an unknown coefficient in the Maxwell's equations,…

Computer-Aided Diagnosis and Treatment of Tumors is a hot topic of deep learning in recent years, which constitutes a series of medical tasks, such as detection of tumor markers, the outline of tumor leisures, subtypes and stages of tumors,…

图像与视频处理 · 电气工程与系统科学 2020-11-03 Dan Zhao , Guizhi Xu , Zhenghua XU , Thomas Lukasiewicz , Minmin Xue , Zhigang Fu

An initial-boundary value problem for the time-fractional diffusion equation is discretized in space using continuous piecewise-linear finite elements on a polygonal domain with a re-entrant corner. Known error bounds for the case of a…

数值分析 · 数学 2017-12-21 Kim Ngan Le , William McLean , Bishnu Lamichhane

In cancer, treatment failure and disease recurrence have been associated with small subpopulations of cancer cells with a stem-like phenotype. In this paper, we develop and investigate a phenotype-structured model of solid tumour growth in…

细胞行为 · 定量生物学 2021-01-15 Giulia L. Celora , Helen M. Byrne , Christos Zois , Panos G. Kevrekidis

The discovery of molecules with tailored optoelectronic properties such as specific frequency and intensity of absorption or emission is a major challenge in creating next-generation organic light-emitting diodes (OLEDs) and photovoltaics.…

化学物理 · 物理学 2022-04-27 James David Green , Eric Gabriel Fuemmeler , Timothy J. H. Hele

The tumour microenvironment plays a fundamental role in understanding the development and progression of cancer. This paper proposes a novel spatial point process model that accounts for inhomogeneity and interaction to flexibly model a…

应用统计 · 统计学 2023-07-13 Jonatan A. González , Paula Moraga

We consider the inverse problem of reconstructing inhomogeneities by performing a finite number of scattering measurements of acoustic type in the time-harmonic setting. We set up the reconstruction as a fully discrete variational problem…

偏微分方程分析 · 数学 2026-02-24 Daniela Di Donato , Luca Rondi

In this work we investigate a mathematical model describing tumour growth under a treatment by chemotherapy that incorporates time-delay related to the conversion from resting to hunting cells. We study the model using values for the…

组织与器官 · 定量生物学 2013-12-09 F. S. Borges , K. C. Iarosz , H. P. Ren , A. M. Batista , M. S. Baptista , R. L. Viana , S. R. Lopes , C. Grebogi

Heterogeneity is a hallmark of all cancers. Tumor heterogeneity is found at different levels -- interpatient, intrapatient, and intratumor heterogeneity. All of them pose challenges for clinical treatments. The latter two scenarios can also…

软凝聚态物质 · 物理学 2020-04-03 Xin Li , D. Thirumalai

Phase retrieval is a nonlinear inverse problem that arises in a wide range of imaging modalities, from electron microscopy to Fourier ptychography. In particular, the reconstruction is facilitated when the sensing matrix is i.i.d. random,…

The probabilistic diffusion model (DM), generating content by inferencing through a recursive chain structure, has emerged as a powerful framework for visual generation. After pre-training on enormous data, the model needs to be properly…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Tao Ren , Zishi Zhang , Jingyang Jiang , Zehao Li , Shentao Qin , Yi Zheng , Guanghao Li , Qianyou Sun , Yan Li , Jiafeng Liang , Xinping Li , Yijie Peng

Recently, diffusion models have been used to solve various inverse problems in an unsupervised manner with appropriate modifications to the sampling process. However, the current solvers, which recursively apply a reverse diffusion step…

机器学习 · 计算机科学 2024-05-21 Hyungjin Chung , Byeongsu Sim , Dohoon Ryu , Jong Chul Ye

High-energy physics is replete with hard computational problems and it is one of the areas where quantum computing could be used to speed up calculations. We present an implementation of likelihood-based regularized unfolding on a quantum…

数据分析、统计与概率 · 物理学 2020-10-09 Kyle Cormier , Riccardo Di Sipio , Peter Wittek

Glioma, an aggressive brain malignancy characterized by rapid progression and its poor prognosis, poses significant challenges for accurate evolution prediction. These challenges are exacerbated by sparse, irregularly acquired longitudinal…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Aghiles Kebaili , Romain Modzelewski , Jérôme Lapuyade-Lahorgue , Maxime Fontanilles , Sébastien Thureau , Su Ruan

Recovering high-dimensional signals from corrupted measurements is a central challenge in inverse problems. Recent advances in generative diffusion models have shown remarkable empirical success in providing strong data-driven priors, but…

机器学习 · 计算机科学 2025-09-26 Oscar Leong , Yann Traonmilin

Inverse problems arise in a multitude of applications, where the goal is to recover a clean signal from noisy and possibly (non)linear observations. The difficulty of a reconstruction problem depends on multiple factors, such as the ground…

图像与视频处理 · 电气工程与系统科学 2024-08-21 Zalan Fabian , Berk Tinaz , Mahdi Soltanolkotabi

Chemotaxis is the process by which cells behave in a way that follows the chemical gradient. Applications to bacteria growth, tissue inflammation, and vascular tumors provide a focus on optimization strategies. Experiments can characterize…

最优化与控制 · 数学 2007-07-18 K. Renee Fister , Maeve L. McCarthy
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