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Methods for addressing missing data have become much more accessible to applied researchers. However, little guidance exists to help researchers systematically identify plausible missing data mechanisms in order to ensure that these methods…

应用统计 · 统计学 2020-07-29 Adam Davey , Ting Dai

Systems of interacting particles or agents have wide applications in many disciplines such as Physics, Chemistry, Biology and Economics. These systems are governed by interaction laws, which are often unknown: estimating them from…

机器学习 · 统计学 2020-07-16 Fei Lu , Mauro Maggioni , Sui Tang

Many collective systems exist in nature far from equilibrium, ranging from cellular sheets up to flocks of birds. These systems reflect a form of active matter, whereby individual material components have internal energy. Under specific…

软凝聚态物质 · 物理学 2023-04-17 Namid R. Stillman , Silke Henkes , Roberto Mayor , Gilles Louppe

We propose a geometric model-free causality measurebased on multivariate delay embedding that can efficiently detect linear and nonlinear causal interactions between time series with no prior information. We then exploit the proposed causal…

神经与进化计算 · 计算机科学 2016-07-26 Saba Emrani , Hamid Krim

Biological networks have so many possible states that exhaustive sampling is impossible. Successful analysis thus depends on simplifying hypotheses, but experiments on many systems hint that complicated, higher order interactions among…

神经元与认知 · 定量生物学 2009-11-11 Elad Schneidman , Michael J. Berry , Ronen Segev , William Bialek

Metamorphic testing is a testing method for problems without test oracles. Integration testing allows for detecting errors in complex systems that may not be found during the testing of their components. In this paper, we propose a novel…

软件工程 · 计算机科学 2023-05-02 Sofia F. Yakusheva , Anton S. Khritankov

Molecular simulations and biophysical experiments can be used to provide independent and complementary insights into the molecular origin of biological processes. A particularly useful strategy is to use molecular simulations as a modelling…

化学物理 · 物理学 2019-12-10 Simone Orioli , Andreas Haahr Larsen , Sandro Bottaro , Kresten Lindorff-Larsen

From an enactive approach, some previous studies have demonstrated that social interaction plays a fundamental role in the dynamics of neural and behavioral complexity of embodied agents. In particular, it has been shown that agents with a…

多智能体系统 · 计算机科学 2020-11-04 Georgina Montserrat Reséndiz-Benhumea , Ekaterina Sangati , Tom Froese

Phase separation has emerged as an essential concept for the spatial organization inside biological cells. However, despite the clear relevance to virtually all physiological functions, we understand surprisingly little about what phases…

生物物理 · 物理学 2022-08-10 David Zwicker , Liedewij Laan

The ability to detect weak distributed activation patterns in networks is critical to several applications, such as identifying the onset of anomalous activity or incipient congestion in the Internet, or faint traces of a biochemical spread…

信息论 · 计算机科学 2010-03-02 Aarti Singh , Robert D. Nowak , Robert Calderbank

Social scientists are increasingly turning to unstructured datasets to unlock new empirical insights, e.g., estimating descriptive statistics of or causal effects on quantitative measures derived from text, audio, or video data. In many…

计量经济学 · 经济学 2026-05-06 Jacob Carlson

Mixed data refers to a type of data in which variables can be of multiple types, such as continuous, discrete, or categorical. This data is routinely collected in various fields, including healthcare and social sciences. A common goal in…

统计方法学 · 统计学 2025-05-22 Mauro Florez , Anna Gottard , Carrie McAdams , Michele Guindani , Marina Vannucci

We introduce kernel nonparametric tests for Lancaster three-variable interaction and for total independence, using embeddings of signed measures into a reproducing kernel Hilbert space. The resulting test statistics are straightforward to…

统计方法学 · 统计学 2013-06-11 Dino Sejdinovic , Arthur Gretton , Wicher Bergsma

Scientific practice typically involves repeatedly studying a system, each time trying to unravel a different perspective. In each study, the scientist may take measurements under different experimental conditions (interventions,…

机器学习 · 统计学 2014-03-11 Sofia Triantafillou , Ioannis Tsamardinos

Hypergraphs, encoding structured interactions among any number of system units, have recently proven a successful tool to describe many real-world biological and social networks. Here we propose a framework based on statistical inference to…

社会与信息网络 · 计算机科学 2022-12-01 Martina Contisciani , Federico Battiston , Caterina De Bacco

Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major…

神经元与认知 · 定量生物学 2018-01-23 Taishi Iwasaki , Hideitsu Hino , Masami Tatsuno , Shotaro Akaho , Noboru Murata

Studying systems where many individual bodies in motion interact with one another is a complex and interesting area. Simple mechanisms that may be determined for biological, chemical, or physical reasons can lead to astonishingly complex…

定量方法 · 定量生物学 2023-01-03 Cameron McNamee , Renee Reijo Pera

Temporally evolving systems are typically modeled by dynamic equations. A key challenge in accurate modeling is understanding the causal relationships between subsystems, as well as identifying the presence and influence of unobserved…

统计方法学 · 统计学 2024-10-28 András Telcs , Marcell T. Kurbucz , Antal Jakovác

No man is an island, as individuals interact and influence one another daily in our society. When social influence takes place in experiments on a population of interconnected individuals, the treatment on a unit may affect the outcomes of…

统计方法学 · 统计学 2017-08-30 Edward K. Kao

Causal discovery from data affected by unobserved variables is an important but difficult problem to solve. The effects that unobserved variables have on the relationships between observed variables are more complex in nonlinear cases than…

机器学习 · 计算机科学 2021-06-07 Takashi Nicholas Maeda , Shohei Shimizu