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相关论文: Mapping Patient Trajectories: Understanding and Vi…

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Designing reward functions for reinforcement learning (RL) in healthcare remains challenging because clinically meaningful outcomes are sparse, delayed, and difficult to explicitly specify. Although structured clinical data capture…

Sepsis remains one of the most complex and heterogeneous syndromes in intensive care, characterized by diverse physiological trajectories and variable responses to treatment. While deep learning models perform well in the early prediction…

机器学习 · 计算机科学 2026-04-01 Vincent Lemaire , Nédra Meloulli , Pierre Jaquet

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

神经元与认知 · 定量生物学 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor

Physicians work at a very tight schedule and need decision-making support tools to help on improving and doing their work in a timely and dependable manner. Examining piles of sheets with test results and using systems with little…

The sequence of visits and procedures performed by the patient in the health system, also known as the patient's pathway or trajectory, can reveal important information about the clinical treatment adopted and the health service provided.…

The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate predictions about patient state from clinical measurements has…

定量方法 · 定量生物学 2020-07-30 Dale Larie , Gary An , Chase Cockrell

Sepsis is a life-threatening disease with high morbidity, mortality and healthcare costs. The early prediction and administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis and can save…

计算与语言 · 计算机科学 2021-07-26 Fred Qin , Vivek Madan , Ujjwal Ratan , Zohar Karnin , Vishaal Kapoor , Parminder Bhatia , Taha Kass-Hout

Applying methods in natural language processing on electronic health records (EHR) data is a growing field. Existing corpus and annotation focus on modeling textual features and relation prediction. However, there is a paucity of annotated…

计算与语言 · 计算机科学 2022-04-08 Yanjun Gao , Dmitriy Dligach , Timothy Miller , Samuel Tesch , Ryan Laffin , Matthew M. Churpek , Majid Afshar

Sepsis is a serious, life-threatening condition. When treating sepsis, it is challenging to determine the correct amount of intravenous fluids and vasopressors for a given patient. While automated reinforcement learning (RL)-based methods…

机器学习 · 计算机科学 2025-09-04 Taisiya Khakharova , Lucas Sakizloglou , Leen Lambers

Forecasting how a patient's condition is likely to evolve, including possible deterioration, recovery, treatment needs, and care transitions, could support more proactive and personalized care, but requires modeling heterogeneous and…

机器学习 · 计算机科学 2026-03-26 Chantal Pellegrini , Ege Özsoy , David Bani-Harouni , Matthias Keicher , Nassir Navab

Characterizing a patient's progression through stages of sepsis is critical for enabling risk stratification and adaptive, personalized treatment. However, commonly used sepsis diagnostic criteria fail to account for significant underlying…

Employing a machine learning approach we predict, up to 24 hours prior, a diagnosis of severe sepsis. Strongly predictive models are possible that use only text reports from the Electronic Health Record (EHR), and omit structured numerical…

计算机与社会 · 计算机科学 2017-12-01 Phil Culliton , Michael Levinson , Alice Ehresman , Joshua Wherry , Jay S. Steingrub , Stephen I. Gallant

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

机器学习 · 计算机科学 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Sepsis is an important cause of mortality, especially in intensive care unit (ICU) patients. Developing novel methods to identify early mortality is critical for improving survival outcomes in sepsis patients. Using the MIMIC-III database,…

计算机与社会 · 计算机科学 2021-12-03 Jiyoung Shin , Yikuan Li , Yuan Luo

Electronic Health Records (EHRs) aggregate diverse information at the patient level, holding a trajectory representative of the evolution of the patient health status throughout time. Although this information provides context and can be…

机器学习 · 计算机科学 2022-09-12 João Figueira Silva , Sérgio Matos

Disease prediction holds considerable significance in modern healthcare, because of its crucial role in facilitating early intervention and implementing effective prevention measures. However, most recent disease prediction approaches…

计算与语言 · 计算机科学 2024-05-07 Zhixiang Su , Yinan Zhang , Jiazheng Jing , Jie Xiao , Zhiqi Shen

COVID-19 has caused thousands of deaths around the world and also resulted in a large international economic disruption. Identifying the pathways associated with this illness can help medical researchers to better understand the properties…

计算与语言 · 计算机科学 2022-05-03 Negin Karisani , Daniel E. Platt , Saugata Basu , Laxmi Parida

Healthcare providers face significant challenges with monitoring and managing patient data outside of clinics, particularly with insufficient resources and limited feedback on their patients' conditions. Effective management of these…

数据库 · 计算机科学 2023-11-14 Daniel Bloor , Nnamdi Ugwuoke , David Taylor , Keir Lewis , Luis Mur , Chuan Lu

The concept of care pathways is increasingly being used to enhance the quality of care and to optimize the use of resources for health care. Nevertheless, recommendations regarding the sequence of care are mostly based on consensus-based…

统计方法学 · 统计学 2022-09-12 Laura Savaré , Francesca Ieva , Giovanni Corrao , Antonio Lora

Electronic health records (EHRs) store an extensive array of patient information, encompassing medical histories, diagnoses, treatments, and test outcomes. These records are crucial for enabling healthcare providers to make well-informed…

计算与语言 · 计算机科学 2023-08-07 Yu-Neng Chuang , Ruixiang Tang , Xiaoqian Jiang , Xia Hu
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