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Serous borderline ovarian tumor (SBOT) and high-grade serous ovarian cancer (HGSOC) are two distinct subtypes of epithelial ovarian tumors, with markedly different biologic background, behavior, prognosis, and treatment. However, the…

图像与视频处理 · 电气工程与系统科学 2020-08-31 Jun Jiang , Burak Tekin , Ruifeng Guo , Hongfang Liu , Yajue Huang , Chen Wang

Semi-supervised clustering techniques have emerged as valuable tools for leveraging prior information in the form of constraints to improve the quality of clustering outcomes. Despite the proliferation of such methods, the ability to…

机器学习 · 计算机科学 2023-12-19 Guangjie Zeng , Hao Peng , Angsheng Li , Zhiwei Liu , Runze Yang , Chunyang Liu , Lifang He

Single-cell RNA sequencing (scRNA-seq) reveals cell heterogeneity, with cell clustering playing a key role in identifying cell types and marker genes. Recent advances, especially graph neural networks (GNNs)-based methods, have…

基因组学 · 定量生物学 2025-10-03 Ping Xu , Zhiyuan Ning , Pengjiang Li , Wenhao Liu , Pengyang Wang , Jiaxu Cui , Yuanchun Zhou , Pengfei Wang

Self-supervised heterogeneous graph learning (SHGL) has shown promising potential in diverse scenarios. However, while existing SHGL methods share a similar essential with clustering approaches, they encounter two significant limitations:…

人工智能 · 计算机科学 2024-12-03 Yujie Mo , Zhihe Lu , Runpeng Yu , Xiaofeng Zhu , Xinchao Wang

Practitioners from many disciplines (e.g., political science) use expert-crafted taxonomies to make sense of large, unlabeled corpora. In this work, we study Seeded Hierarchical Clustering (SHC): the task of automatically fitting unlabeled…

计算与语言 · 计算机科学 2022-05-25 Anish Saha , Amith Ananthram , Emily Allaway , Heng Ji , Kathleen McKeown

Self organizing maps (SOMs) are widely-used for unsupervised classification. For this application, they must be combined with some partitioning scheme that can identify boundaries between distinct regions in the maps they produce. We…

神经与进化计算 · 计算机科学 2008-02-07 Paul R. Gazis , Jeffrey D. Scargle

The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the…

定量方法 · 定量生物学 2021-09-21 Pingjun Chen , Muhammad Aminu , Siba El Hussein , Joseph D. Khoury , Jia Wu

Liver cancer is a leading cause of cancer-related mortality worldwide, with its high genetic heterogeneity complicating diagnosis and treatment. This study introduces DLSOM, a deep learning framework utilizing stacked autoencoders to…

基因组学 · 定量生物学 2024-12-18 Fabio Zamio

Hyperspectral image (HSI) clustering groups pixels into clusters without labeled data, which is an important yet challenging task. For large-scale HSIs, most methods rely on superpixel segmentation and perform superpixel-level clustering…

计算机视觉与模式识别 · 计算机科学 2025-11-21 Jianhan Qi , Yuheng Jia , Hui Liu , Junhui Hou

Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…

定量方法 · 定量生物学 2022-08-12 Richard Tjörnhammar

We present an application of unsupervised machine learning - the self-organised map (SOM) - as a tool for visualising, exploring and mining the catalogues of large astronomical surveys. Self-organisation culminates in a low-resolution…

天体物理仪器与方法 · 物理学 2015-05-30 James E. Geach

In high-performance computing (HPC) environments, system monitoring data is often unlabeled and high-dimensional, making it difficult to reliably detect and understand anomalous computing nodes. The growing scale and dimensionality of the…

分布式、并行与集群计算 · 计算机科学 2026-04-15 Allison Austin , Shilpika , Yan To Linus Lam , Yun-Hsin Kuo , Venkatram Vishwanath , Michael E. Papka , Kwan-Liu Ma

Spectral clustering is a powerful tool for unsupervised data analysis. In this paper, we propose a context-aware hypergraph similarity measure (CAHSM), which leads to robust spectral clustering in the case of noisy data. We construct three…

计算机视觉与模式识别 · 计算机科学 2016-11-15 Xi Li , Weiming Hu , Chunhua Shen , Anthony Dick , Zhongfei Zhang

We uncover that current objective-based Divisive Hierarchical Clustering (DHC) methods produce a dendrogram that does not have three desired properties i.e., no unwarranted splitting, group similar clusters into a same subset, ground-truth…

机器学习 · 计算机科学 2026-01-28 Kaifeng Zhang , Kai Ming Ting , Tianrun Liang , Qiuran Zhao

Subspace clustering is a powerful unsupervised approach for hyperspectral image (HSI) analysis, but its high computational and memory costs limit scalability. Superpixel segmentation can improve efficiency by reducing the number of data…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Xianlu Li , Nicolas Nadisic , Shaoguang Huang , Aleksandra Pizurica

In several environmental applications data are functions of time, essentially con- tinuous, observed and recorded discretely, and spatially correlated. Most of the methods for analyzing such data are extensions of spatial statistical tools…

统计方法学 · 统计学 2011-06-28 Elvira Romano , Antonio Balzanella , Rosanna Verde

This work describes the implementation and application of a correlation determination method based on Self Organizing Maps and Bayesian Inference (SOMBI). SOMBI aims to automatically identify relations between different observed parameters…

宇宙学与河外天体物理 · 物理学 2016-11-02 Philipp Frank , Jens Jasche , Torsten A. Enßlin

In this paper, we consider feature screening for ultrahigh dimensional clustering analyses. Based on the observation that the marginal distribution of any given feature is a mixture of its conditional distributions in different clusters, we…

统计方法学 · 统计学 2024-02-05 Changhu Wang , Zihao Chen , Ruibin Xi

Clustering and visualizing high-dimensional (HD) data are important tasks in a variety of fields. For example, in bioinformatics, they are crucial for analyses of single-cell data such as mass cytometry (CyTOF) data. Some of the most…

定量方法 · 定量生物学 2021-07-19 Joshua M. Scurll