相关论文: scGHSOM: Hierarchical clustering and visualization…

Gene expression datasets consist of thousand of genes with relatively small samplesizes (i.e. are large-$p$-small-$n$). Moreover, dependencies of various orders co-exist in the datasets. In the Undirected probabilistic Graphical Model (UGM)…

There have been several attempts to develop Feature Selection (FS) algorithms capable of identifying features that are relevant in a dataset. Although in certain applications the FS algorithms can be seen to be successful, they have similar…

Motivated by high-throughput single-cell cytometry data with applications to vaccine development and immunological research, we consider statistical clustering in large-scale data that contain multiple rare clusters. We propose a new…

Object re-identification method is made up of backbone network, feature aggregation, and loss function. However, most backbone networks lack a special mechanism to handle rich scale variations and mine discriminative feature…

In this paper, we present novel variations of an earlier approach called homogeneous clustering algorithm for reducing dataset size. The intuition behind the approaches proposed in this paper is to partition the dataset into homogeneous…

We consider the analysis of high dimensional data given in the form of a matrix with columns consisting of observations and rows consisting of features. Often the data is such that the observations do not reside on a regular grid, and the…

Clustering genotypes based upon their phenotypic characteristics is used to obtain diverse sets of parents that are useful in their breeding programs. The Hierarchical Clustering (HC) algorithm is the current standard in clustering of…

Spectral clustering is a powerful technique for clustering high-dimensional data, utilizing graph-based representations to detect complex, non-linear structures and non-convex clusters. The construction of a similarity graph is essential…

This paper focuses on density-based clustering, particularly the Density Peak (DP) algorithm and the one based on density-connectivity DBSCAN; and proposes a new method which takes advantage of the individual strengths of these two methods…

We propose a novel method, scTree, for single-cell Tree Variational Autoencoders, extending a hierarchical clustering approach to single-cell RNA sequencing data. scTree corrects for batch effects while simultaneously learning a…

Interpretability is a key issue when applying deep learning models to longitudinal brain MRIs. One way to address this issue is by visualizing the high-dimensional latent spaces generated by deep learning via self-organizing maps (SOM). SOM…

Hierarchical clustering is a fundamental task often used to discover meaningful structures in data, such as phylogenetic trees, taxonomies of concepts, subtypes of cancer, and cascades of particle decays in particle physics. Typically…

Classification in the dissimilarity space has become a very active research area since it provides a possibility to learn from data given in the form of pairwise non-metric dissimilarities, which otherwise would be difficult to cope with.…

We consider joint estimation of multiple graphical models arising from heterogeneous and high-dimensional observations. Unlike most previous approaches which assume that the cluster structure is given in advance, an appealing feature of our…

Glioblastoma is a highly aggressive form of brain cancer characterized by rapid progression and poor prognosis. Despite advances in treatment, the underlying genetic mechanisms driving this aggressiveness remain poorly understood. In this…

Unsupervised semantic segmentation aims to discover groupings within and across images that capture object and view-invariance of a category without external supervision. Grouping naturally has levels of granularity, creating ambiguity in…

Finding a set of nested partitions of a dataset is useful to uncover relevant structure at different scales, and is often dealt with a data-dependent methodology. In this paper, we introduce a general two-step methodology for model-based…

The human visual perception system demonstrates exceptional capabilities in learning without explicit supervision and understanding the part-to-whole composition of objects. Drawing inspiration from these two abilities, we propose…

Over the last decade, a large variety of clustering algorithms have been developed to detect coregulatory relationships among genes from microarray gene expression data. Model based clustering approaches have emerged as statistically well…

Semantic segmentation of electron microscopy (EM) images of biological samples remains a challenge in the life sciences. EM data captures details of biological structures, sometimes with such complexity that even human observers can find it…