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We present simple conditions under which the limiting genealogical process associated with a class of interacting particle systems with non-neutral selection mechanisms, as the number of particles grows, is a time-rescaled Kingman…

统计计算 · 统计学 2020-12-08 Suzie Brown , Paul A. Jenkins , Adam M. Johansen , Jere Koskela

We study weighted particle systems in which new generations are resampled from current particles with probabilities proportional to their weights. This covers a broad class of sequential Monte Carlo (SMC) methods, widely-used in applied…

统计理论 · 数学 2021-07-20 Jere Koskela , Paul A. Jenkins , Adam M. Johansen , Dario Spano

Interacting particle systems undergoing repeated mutation and selection steps model genetic evolution, and also describe a broad class of sequential Monte Carlo methods. The genealogical tree embedded into the system is important in both…

概率论 · 数学 2023-04-20 Suzie Brown , Paul A. Jenkins , Adam M. Johansen , Jere Koskela

We propose a new algorithm to do posterior sampling of Kingman's coalescent, based upon the Particle Markov Chain Monte Carlo methodology. Specifically, the algorithm is an instantiation of the Particle Gibbs Sampling method, which…

机器学习 · 统计学 2013-05-07 Yifei Chen , Xiaohui Xie

Sweepstakes reproduction may be generated by chance matching of reproduction with favorable environmental conditions. Gene genealogies generated by sweepstakes reproduction are in the domain of attraction of multiple-merger coalescents…

概率论 · 数学 2026-01-15 Bjarki Eldon

Statistical inference of evolutionary parameters from molecular sequence data relies on coalescent models to account for the shared genealogical ancestry of the samples. However, inferential algorithms do not scale to available data sets. A…

应用统计 · 统计学 2019-09-10 Lorenzo Cappello , Julia A. Palacios

The genealogy at a single locus of a constant size $N$ population in equilibrium is given by the well-known Kingman's coalescent. When considering multiple loci under recombination, the ancestral recombination graph encodes the genealogies…

概率论 · 数学 2015-11-10 Andrej Depperschmidt , Etienne Pardoux , Peter Pfaffelhuber

The Kingman coalescent is a fundamental process in population genetics modelling the ancestry of a sample of individuals backwards in time. In this paper, in a large-sample-size regime, we study asymptotic properties of the coalescent under…

概率论 · 数学 2025-03-17 Martina Favero , Henrik Hult

Sequential Monte Carlo (SMC) methods are a class of techniques to sample approximately from any sequence of probability distributions using a combination of importance sampling and resampling steps. This paper is concerned with the…

统计理论 · 数学 2012-03-05 Pierre Del Moral , Arnaud Doucet , Ajay Jasra

A well-established model for the genealogy of a large population in equilibrium is Kingman's coalescent. For the population together with its genealogy evolving in time, this gives rise to a time-stationary tree-valued process. We study the…

概率论 · 数学 2010-05-18 Peter Pfaffelhuber , Anton Wakolbinger , Heinz Weisshaupt

Trees corresponding to $\Lambda$- and $\Xi$-$n$-coalescents can be both quite similar and fundamentally different compared to bifurcating tree models based on Kingman's $n$-coalescent. This has consequences for inference of a well-fitting…

概率论 · 数学 2020-10-26 Fabian Freund

Multiple-merger coalescents, e.g. $\Lambda$-$n$-coalescents, have been proposed as models of the genealogy of $n$ sampled individuals for a range of populations whose genealogical structures are not captured well by Kingman's…

概率论 · 数学 2021-04-19 Fabian Freund

Coalescent processes, including mutation, are derived from Moran type population models admitting large offspring numbers. Including mutation in the coalescent process allows for quantifying the turnover of alleles by computing the…

种群与进化 · 定量生物学 2012-12-11 Bjarki Eldon

Generative models derived from large protein sequence alignments define complex fitness landscapes, but their utility for accurately modeling non-equilibrium evolutionary dynamics remains unclear. In this work, we perform a rigorous…

种群与进化 · 定量生物学 2026-02-10 Leonardo Di Bari , Thierry Mora , Andrea Pagnani , Aleksandra M. Walczak , Francesco Zamponi , Saverio Rossi

In the case of neutral populations of fixed sizes in equilibrium whose genealogies are described by the Kingman $N$-coalescent back from time $t$ consider the associated processes of total tree length as $t$ increases. We show that the…

概率论 · 数学 2015-02-03 Iulia Dahmer , Robert Knobloch , Anton Wakolbinger

We introduce a new Bayesian model for hierarchical clustering based on a prior over trees called Kingman's coalescent. We develop novel greedy and sequential Monte Carlo inferences which operate in a bottom-up agglomerative fashion. We show…

机器学习 · 统计学 2009-07-07 Yee Whye Teh , Hal Daumé , Daniel Roy

We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially…

种群与进化 · 定量生物学 2012-11-06 Matthias Steinrücken , Matthias Birkner , Jochen Blath

The development of coalescent theory paved the way to statistical inference from population genetic data. In the genomic era, however, coalescent models are limited due to the complexity of the underlying ancestral recombination graph. The…

种群与进化 · 定量生物学 2021-06-30 Julien Y. Dutheil

A method was developed for Bayesian inference of species phylogeny using the multi-species coalescent model. To improve the mixing properties of the Markov chain Monte Carlo (MCMC) algorithm that traverses the space of species trees, we…

种群与进化 · 定量生物学 2015-12-15 Bruce Rannala , Ziheng Yang

In this paper we present an extension of population-based Markov chain Monte Carlo (MCMC) to the trans-dimensional case. One of the main challenges in MCMC-based inference is that of simulating from high and trans-dimensional target…

统计计算 · 统计学 2007-11-02 Ajay Jasra , David A. Stephens , Chris C. Holmes
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