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Stochastic evolution of Chemical Reactions Networks (CRNs) over time is usually analysed through solving the Chemical Master Equation (CME) or performing extensive simulations. Analysing stochasticity is often needed, particularly when some…

计算机科学中的逻辑 · 计算机科学 2015-09-11 Luca Laurenti , Luca Cardelli , Marta Kwiatkowska

We consider inference for the reaction rates in discretely observed networks such as those found in models for systems biology, population ecology and epidemics. Most such networks are neither slow enough nor small enough for inference via…

统计方法学 · 统计学 2014-02-05 Paul Fearnhead , Vasileios Giagos , Chris Sherlock

This study concerns online inference (i.e., filtering) on the state of reaction networks, conditioned on noisy and partial measurements. The difficulty in deriving the equation that the conditional probability distribution of the state…

统计方法学 · 统计学 2016-11-03 Shinsuke Koyama

The transition density of a stochastic, logistic population growth model with multiplicative intrinsic noise is analytically intractable. Inferring model parameter values by fitting such stochastic differential equation (SDE) models to data…

应用统计 · 统计学 2015-08-17 Jonathan Heydari , Conor Lawless , David A. Lydall , Darren J. Wilkinson

We consider the problem of efficiently performing simulation and inference for stochastic kinetic models. Whilst it is possible to work directly with the resulting Markov jump process, computational cost can be prohibitive for networks of…

统计计算 · 统计学 2015-06-18 Chris Sherlock , Andrew Golightly , Colin Gillespie

The linear noise approximation (LNA) offers a simple means by which one can study intrinsic noise in monostable biochemical networks. Using simple physical arguments, we have recently introduced the slow-scale LNA (ssLNA) which is a reduced…

统计力学 · 物理学 2012-11-08 Philipp Thomas , Ramon Grima , Arthur V. Straube

We propose an online learning algorithm for a class of machine learning models under a separable stochastic approximation framework. The essence of our idea lies in the observation that certain parameters in the models are easier to…

机器学习 · 计算机科学 2023-05-23 Min Gan , Xiang-xiang Su , Guang-yong Chen , Jing Chen

Fluorescent and luminescent gene reporters allow us to dynamically quantify changes in molecular species concentration over time on the single cell level. The mathematical modeling of their interaction through multivariate dynamical models…

定量方法 · 定量生物学 2009-07-07 Michal Komorowski , Barbel Finkenstadt , Claire V. Harper , David A. Rand

Likelihood-based inference in stochastic non-linear dynamical systems, such as those found in chemical reaction networks and biological clock systems, is inherently complex and has largely been limited to small and unrealistically simple…

统计计算 · 统计学 2024-07-08 Ben Swallow , David A. Rand , Giorgos Minas

We introduce a novel combination of Bayesian Models (BMs) and Neural Networks (NNs) for making predictions with a minimum expected risk. Our approach combines the best of both worlds, the data efficiency and interpretability of a BM with…

机器学习 · 计算机科学 2021-09-28 Mathias Löwe , Per Lunnemann Hansen , Sebastian Risi

We propose using recognition networks for approximate inference inBayesian networks (BNs). A recognition network is a multilayerperception (MLP) trained to predict posterior marginals given observedevidence in a particular BN. The input to…

人工智能 · 计算机科学 2013-01-14 Quaid Morris

Physics-informed neural networks (PINNs) were recently proposed in [1] as an alternative way to solve partial differential equations (PDEs). A neural network (NN) represents the solution while a PDE-induced NN is coupled to the solution NN,…

计算物理 · 物理学 2019-10-22 Xiaoli Chen , Jinqiao Duan , George Em Karniadakis

In this work, we aim to enhance the system robustness of end-to-end automatic speech recognition (ASR) against adversarially-noisy speech examples. We focus on a rigorous and empirical "closed-model adversarial robustness" setting (e.g.,…

音频与语音处理 · 电气工程与系统科学 2022-02-18 Chao-Han Huck Yang , Zeeshan Ahmed , Yile Gu , Joseph Szurley , Roger Ren , Linda Liu , Andreas Stolcke , Ivan Bulyko

In processing and manufacturing industries, there has been a large push to produce higher quality products and ensure maximum efficiency of processes. This requires approaches to effectively detect and resolve disturbances to ensure optimal…

机器学习 · 统计学 2021-02-05 Weike Sun , Antonio R. C. Paiva , Peng Xu , Anantha Sundaram , Richard D. Braatz

Deep learning has been the engine powering many successes of data science. However, the deep neural network (DNN), as the basic model of deep learning, is often excessively over-parameterized, causing many difficulties in training,…

机器学习 · 统计学 2021-03-09 Yan Sun , Qifan Song , Faming Liang

The increased flexibility and density of spectrum access in 5G New Radio (NR) has made jamming detection and classification a critical research area. To detect coexisting jamming and subtle interference, we introduce a Bayesian…

信号处理 · 电气工程与系统科学 2024-10-28 Shashank Jere , Ying Wang , Ishan Aryendu , Shehadi Dayekh , Lingjia Liu

In this work, we present an extension to the context of Stochastic Reaction Networks (SRNs) of the forward-reverse representation introduced in "Simulation of forward-reverse stochastic representations for conditional diffusions", a 2014…

数值分析 · 数学 2015-04-17 Christian Bayer , Alvaro Moraes , Raul Tempone , Pedro Vilanova

In this article, we introduce and analyze a deep learning based approximation algorithm for SPDEs. Our approach employs neural networks to approximate the solutions of SPDEs along given realizations of the driving noise process. If applied…

This paper proposes a sparse Bayesian treatment of deep neural networks (DNNs) for system identification. Although DNNs show impressive approximation ability in various fields, several challenges still exist for system identification…

系统与控制 · 电气工程与系统科学 2022-06-02 Hongpeng Zhou , Chahine Ibrahim , Wei Xing Zheng , Wei Pan

Localizing more sources than sensors with a sparse linear array (SLA) has long relied on minimizing a distance between two covariance matrices and recent algorithms often utilize semidefinite programming (SDP). Although deep neural network…

信号处理 · 电气工程与系统科学 2025-03-11 Kuan-Lin Chen , Bhaskar D. Rao
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