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For the description of a pandemic mathematical models could be interesting. Both for physicians and politicians as a base for decisions to treat the disease. The responsible estimation of parameters is a main issue of mathematical pandemic…

种群与进化 · 定量生物学 2020-04-15 Günter Bärwolff

The rapidly spreading Covid-19 that affected almost all countries, was first reported at the end of 2019. As a consequence of its highly infectious nature, countries all over the world have imposed extremely strict measures to control its…

种群与进化 · 定量生物学 2020-07-13 Semra Ahmetolan , Ayse Humeyra Bilge , Ali Demirci , Ayse Peker-Dobie , Onder Ergonul

We present a modelling framework for the spreading of epidemics on temporal networks from which both the individual-based and pair-based models can be recovered. The proposed temporal pair-based model that is systematically derived from…

物理与社会 · 物理学 2020-11-17 Rory Humphries , Kieran Mulchrone , Jamie Tratalos , Simon More , Philipp Hövel

The SIR model is a three-compartment model of the time development of an epidemic. After normalizing the dependent variables, the model is a system of two non-linear differential equations for the susceptible proportion $S$ and the infected…

动力系统 · 数学 2021-04-27 William G. Faris

The effective control of infectious diseases relies on accurate assessment of the impact of interventions, which is often hindered by the complex dynamics of the spread of disease. A Beta-Dirichlet switching state-space transmission model…

统计方法学 · 统计学 2024-04-30 Jingxue Feng , Liangliang Wang

Since 1927, until recently, models describing the spread of disease have mostly been of the SIR-compartmental type, based on the assumption that populations are homogeneous and well-mixed. The focus of these models have typically been on…

物理与社会 · 物理学 2014-07-23 Lara Goscé , David A W Barton , Anders Johansson

Compartmental models like the Susceptible-Infected-Recovered (SIR)\cite{Kermack1927} and its extensions such as the Susceptible-Exposed-Infected-Recovered (SEIRS)\cite{Ottar2020,Ignazio2021,Grimm2021,Paoluzzi2021} are commonly used to model…

种群与进化 · 定量生物学 2025-07-14 Kasturi Banerjee , Subhankar Ray , Jayalakshmi Shamanna

Motivated by the ongoing pandemic COVID-19, we propose a closed-loop framework that combines inference from testing data, learning the parameters of the dynamics and optimal resource allocation for controlling the spread of the…

物理与社会 · 物理学 2021-04-27 Ashish R. Hota , Jaydeep Godbole , Philip E Paré

Epidemics are inherently stochastic, and stochastic models provide an appropriate way to describe and analyse such phenomena. Given temporal incidence data consisting of, for example, the number of new infections or removals in a given time…

统计方法学 · 统计学 2024-05-24 Sam A. Whitaker , Andrew Golightly , Colin S. Gillespie , Theodore Kypraios

Compartmental models are popular in the mathematics of epidemiology for their simplicity and wide range of applications. Although they are typically solved as initial value problems for a system of ordinary differential equations, the…

种群与进化 · 定量生物学 2022-10-12 Eduard Campillo-Funollet , Hayley Wragg , James Van Yperen , Duc-Lam Duong , Anotida Madzvamuse

Multidimensional continuous-time Markov jump processes $(Z(t))$ on $\mathbb{Z}^p$ form a usual set-up for modeling $SIR$-like epidemics. However, when facing incomplete epidemic data, inference based on $(Z(t))$ is not easy to be achieved.…

统计方法学 · 统计学 2014-01-03 Romain Guy , Catherine Larédo , Elisabeta Vergu

The Covid-19 pandemic has made clear the need to improve modern multivariate time-series forecasting models. Current state of the art predictions of future daily deaths and, especially, hospital resource usage have confidence intervals that…

种群与进化 · 定量生物学 2020-06-25 Richard Bao , August Chen , Jethin Gowda , Shiva Mudide

The dramatic outbreak of the coronavirus disease 2019 (COVID-19) pandemics and its ongoing progression boosted the scientific community's interest in epidemic modeling and forecasting. The SIR (Susceptible-Infected-Removed) model is a…

种群与进化 · 定量生物学 2021-02-24 Dimiter Prodanov

The spread of infectious diseases crucially depends on the pattern of contacts among individuals. Knowledge of these patterns is thus essential to inform models and computational efforts. Few empirical studies are however available that…

The estimation from available data of parameters governing epidemics is a major challenge. In addition to usual issues (data often incomplete and noisy), epidemics of the same nature may be observed in several places or over different…

统计方法学 · 统计学 2021-09-20 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

Understanding age-group dynamics of infectious diseases is a fundamental issue for both scientific study and policymaking. Age-structure epidemic models were developed in order to study and improve our understanding of these dynamics. By…

种群与进化 · 定量生物学 2019-11-22 Rami Yaari , Amit Huppert , Itai Dattner

The Susceptible-Infectious-Recovered (SIR) model is the canonical model of epidemics of infections that make people immune upon recovery. Many of the open questions in computational epidemiology concern the underlying contact structure's…

物理与社会 · 物理学 2021-06-09 Petter Holme

During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19,…

The effect of spatial correlations on the spread of infectious diseases was investigated using a stochastic SIR (Susceptible-Infective-Recovered) model on complex networks. It was found that in addition to the reduction of the effective…

种群与进化 · 定量生物学 2007-05-23 J. Verdasca , M. M. Telo da Gama , A. Nunes , N. R. Bernardino , J. M. Pacheco , M. C. Gomes

Identifiability of a mathematical model plays a crucial role in parameterization of the model. In this study, we establish the structural identifiability of a Susceptible-Exposed-Infected-Recovered (SEIR) model given different combinations…