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The discovery of transition pathways to unravel distinct reaction mechanisms and, in general, rare events that occur in molecular systems is still a challenge. Recent advances have focused on analyzing the transition path ensemble using the…

The time-fractional optimal transport (OT) and mean-field planning (MFP) models are developed to describe the anomalous transport of the agents in a heterogeneous environment such that their densities are transported from the initial…

最优化与控制 · 数学 2023-09-06 Yiqun Li , Hong Wang , Wuchen Li

Since its beginnings, fission theory has asumed that low-energy induced fission takes place through transition-state channels at the barrier tops. Neverthess, up to now there is no microscopic theory applicable to those conditions. We…

核理论 · 物理学 2022-04-13 G. F. Bertsch , K. Hagino

Reinforcement Learning (RL) algorithms have achieved remarkable performance in decision making and control tasks due to their ability to reason about long-term, cumulative reward using trial and error. However, during RL training, applying…

机器人学 · 计算机科学 2021-03-03 Yifei Simon Shao , Chao Chen , Shreyas Kousik , Ram Vasudevan

Simulated tempering (ST) has attracted a great deal of attention in the last years, due to its capability to allow systems with complex dynamics to escape from regions separated by large entropic barriers. However its performance is…

统计力学 · 物理学 2015-08-11 A. Valentim , Cláudio J. daSilva , Carlos E. Fiore

Flow-matching models have recently emerged as a powerful framework for continuous generative modeling, including 3D point cloud synthesis. However, their deployment is limited by the need for multiple sequential sampling steps at inference…

Reaction barriers are a crucial ingredient for first principles based computational retro-synthesis efforts as well as for comprehensive reactivity assessments throughout chemical compound space. While extensive databases of experimental…

Mobile robots frequently navigate on roadmaps, i.e., graphs where edges represent safe motions, in applications such as healthcare, hospitality, and warehouse automation. Often the environment is quasi-static, i.e., it is sufficient to…

机器人学 · 计算机科学 2025-04-25 Christian Henkel , Marc Toussaint , Wolfgang Hönig

Standard models of ion channel voltage gating require substantial movement of one transmembrane segment, S4, of the voltage sensing domain. Evidence comes from the accessibility to external methanethiosulfonate (MTS) reagents of the…

生物大分子 · 定量生物学 2013-09-06 Alisher M. Kariev , Michael E. Green

By the adoption of a quaternion orientational order parameter to describe solidification, the topological origins of the thermal transport properties of crystalline and non-crystalline solid states are considered herein. Global…

软凝聚态物质 · 物理学 2019-06-13 Caroline S. Gorham , David E. Laughlin

Computing accurate rate constants for catalytic events occurring at the surface of a given material represents a challenging task with multiple potential applications in chemistry. To address this question, we propose an approach based on a…

It is demonstrated that the transition temperature (Tc) of high-Tc superconductors is determined by their layered crystal structure, bond lengths, valency properties of the ions, and Coulomb coupling between electronic bands in adjacent,…

超导电性 · 物理学 2012-02-03 Dale R. Harshman , Anthony T. Fiory , John D. Dow

Thermal radiative transfer (TRT) presents significant computational challenges due to the stiff, nonlinear coupling between radiation and material energy, particularly in multigroup, high-fidelity transport models. In this work, we develop…

数值分析 · 数学 2026-03-24 Samuel Olivier , James S. Warsa , HyeongKae Park

While sophisticated numerical methods for studying equilibrium states have well advanced, quantitative predictions of kinetic behaviour remain challenging. We introduce a reactant-to-barrier (R2B) machine learning model that rapidly and…

计算物理 · 物理学 2021-08-25 Stefan Heinen , Guido Falk von Rudorff , O. Anatole von Lilienfeld

Reliable and efficient trajectory optimization methods are a fundamental need for autonomous dynamical systems, effectively enabling applications including rocket landing, hypersonic reentry, spacecraft rendezvous, and docking. Within such…

机器人学 · 计算机科学 2024-01-09 Tommaso Guffanti , Daniele Gammelli , Simone D'Amico , Marco Pavone

Stochastic chemical reaction networks (SRNs) in cellular systems are commonly modeled as continuous-time Markov chains (CTMCs) describing the dynamics of molecular copy numbers. The exact evaluation of transient copy number statistics is,…

定量方法 · 定量生物学 2026-04-07 Takeyuki Iwasaki , Yutaka Hori

We introduce RapFlow-TTS, a rapid and high-fidelity TTS acoustic model that leverages velocity consistency constraints in flow matching (FM) training. Although ordinary differential equation (ODE)-based TTS generation achieves…

音频与语音处理 · 电气工程与系统科学 2025-06-23 Hyun Joon Park , Jeongmin Liu , Jin Sob Kim , Jeong Yeol Yang , Sung Won Han , Eunwoo Song

Semiclassical instanton theory is a form of quantum transition-state theory which can be applied to computing thermal reaction rates for complex molecular systems including quantum tunneling effects. There have been a number of attempts to…

化学物理 · 物理学 2020-10-28 Wei Fang , Pierre Winter , Jeremy O. Richardson

We study the Unbalanced Optimal Transport (UOT) between two measures of possibly different masses with at most $n$ components, where the marginal constraints of standard Optimal Transport (OT) are relaxed via Kullback-Leibler divergence…

最优化与控制 · 数学 2024-01-09 Quang Minh Nguyen , Hoang H. Nguyen , Yi Zhou , Lam M. Nguyen

First principle theoretical modeling of out-of-equilibrium processes observed in attosecond pump-probe transient absorption spectroscopy (TAS) triggering pure electron dynamics remains a challenging task, specially for heavy elements and/or…

化学物理 · 物理学 2023-02-14 Torsha Moitra , Lukas Konecny , Marius Kadek , Angel Rubio , Michal Repisky