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Time-resolved three-dimensional flow MRI (4D flow MRI) provides a unique non-invasive solution to visualize and quantify hemodynamics in blood vessels such as the aortic arch. However, most current analysis methods for arterial 4D flow MRI…

计算机视觉与模式识别 · 计算机科学 2024-07-31 Simone Garzia , Patryk Rygiel , Sven Dummer , Filippo Cademartiri , Simona Celi , Jelmer M. Wolterink

To accurately simulate all phases of the cardiac cycle, computational models of hemodynamics in heart chambers need to include a sufficiently faithful model of cardiac valves. This can be achieved efficiently through resistive methods, and…

数值分析 · 数学 2025-06-05 Michele Bucelli , Luca Dede'

We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

数值分析 · 数学 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

Phase-contrast magnetic resonance imaging (MRI) provides time-resolved quantification of blood flow dynamics that can aid clinical diagnosis. Long in vivo scan times due to repeated three-dimensional (3D) volume sampling over cardiac phases…

图像与视频处理 · 电气工程与系统科学 2020-04-22 Valery Vishnevskiy , Jonas Walheim , Sebastian Kozerke

Understanding the complex interplay between morphologic and hemodynamic features in aortic dissection is critical for risk stratification and for the development of individualized therapy. This work evaluates the effects of entry and exit…

Prediction of the blood flow characteristics is of utmost importance for understanding the behavior of the blood arterial network, especially in the presence of vascular diseases such as stenosis. Computational fluid dynamics (CFD) has…

机器学习 · 计算机科学 2021-11-11 Mohammad Farajtabar , Mohit Biglarian , Morteza Miansari

Accurate 3D aortic construction is crucial for clinical diagnosis, preoperative planning, and computational fluid dynamics (CFD) simulations, as it enables the estimation of critical hemodynamic parameters such as blood flow velocity,…

计算机视觉与模式识别 · 计算机科学 2025-07-21 Delin An , Pan Du , Jian-Xun Wang , Chaoli Wang

Endoluminal reconstruction using flow diverters represents a novel paradigm for the minimally invasive treatment of intracranial aneurysms. The configuration assumed by these very dense braided stents once deployed within the parent vessel…

计算工程、金融与科学 · 计算机科学 2023-01-23 Beatrice Bisighini , Miquel Aguirre , Marco Evangelos Biancolini , Federica Trovalusci , David Perrin , Stephane Avril , Baptiste Pierrat

A noteworthy aspect in blood flow modeling is the definition of the mechanical interaction between the fluid flow and the biological structure that contains it, namely the vessel wall. It has been demonstrated that the addition of a viscous…

流体动力学 · 物理学 2022-06-14 Francesco Piccioli , Giulia Bertaglia , Alessandro Valiani , Valerio Caleffi

X-ray Computed Tomography (CT) is used to recover the true surfaces of fluid channels and fed to simulation tool (ANSYS) to create accurate cyber environment. The simulation tool also receives CT-assisted multiphase fluid profiles…

流体动力学 · 物理学 2024-08-06 Vaishali Sharma , Arpit Kumar , Snehlata Shakya , Mayank Goswami

We present a new model and a novel loosely coupled partitioned numerical scheme modeling fluid-structure interaction (FSI) in blood flow allowing non-zero longitudinal displacement. Arterial walls are modeled by a {linearly viscoelastic,…

数值分析 · 数学 2015-06-05 Martina Bukac , Suncica Canic , Roland Glowinski , Josip Tambaca , Annalisa Quaini

A finite element analysis of flows of an Oldroyd-B fluid is developed, to simulate blood flow in an arteriovenous fistula. The model uses a combination of a standard conforming finite element approximation for the momentum equation, and the…

医学物理 · 物理学 2020-03-19 Nkosilathi Vundla , B. Daya Reddy

Physics-based 0D reduced-order models provide computationally lightweight predictions of cardiovascular flows, resolving bulk hemodynamics in fractions of a second that would take days to solve using traditional 3D finite-element…

计算工程、金融与科学 · 计算机科学 2026-04-03 Natalia L. Rubio , Eric F. Darve , Alison L. Marsden

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

In this work, we present a computational fluid-structure interaction (FSI) study for a healthy patient-specific pulmonary arterial tree using the unified continuum and variational multiscale (VMS) formulation we previously developed. The…

计算物理 · 物理学 2020-08-19 Ju Liu , Weiguang Yang , Ingrid S. Lan , Alison L. Marsden

A unified Smoothed Particle Hydrodynamics (SPH) simulation framework for coronary stent implantation is developed, which unifies weakly compressible hemodynamics, Neo-Hookean solids, and stent-artery contacts, based on a multi-resolution…

流体动力学 · 物理学 2025-11-13 Jinlei Zhou , Sukang Peng , Yongchuan Yu , Dong Wu , Xiangyu Hu

Computational fluid dynamics (CFD) can be used for evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep…

计算机视觉与模式识别 · 计算机科学 2025-02-18 Tina Yao , Endrit Pajaziti , Michael Quail , Silvia Schievano , Jennifer A Steeden , Vivek Muthurangu

In this work, we present mixed dimensional models for simulating blood flow and transport processes in breast tissue and the vascular tree supplying it. These processes are considered, to start from the aortic inlet to the capillaries and…

组织与器官 · 定量生物学 2022-10-10 Marvin Fritz , Tobias Köppl , J. Tinsley Oden , Andreas Wagner , Barbara Wohlmuth , Chengyue Wu

The interaction of multiple fluids through a heterogeneous pore space leads to complex pore-scale flow dynamics, such as intermittent pathway flow. The non-local nature of these dynamics, and the size of the 4D datasets acquired to capture…

地球物理 · 物理学 2024-09-24 Aman Raizada , Steffen Berg , Sally M. Benson , Hamdi A. Tchelepi , Catherine Spurin

A reliable and fast numerical scheme is crucial for the 1D simulation of blood flow in compliant vessels. In this paper, a 1D blood flow model is incorporated with a Kelvin-Voigt viscoelastic arterial wall. This leads to a nonlinear…

医学物理 · 物理学 2014-09-17 Xiaofei Wang , Jose-Maria Fullana , Pierre-Yves Lagrée