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Here we characterized an information measure for cell polarity that applies to non-motile cells responding to a chemical gradient. The central idea is that polarization represents information about the direction of the gradient. We applied…

细胞行为 · 定量生物学 2025-04-14 Tau-Mu Yi

Diagnostic tests play a crucial role in medical care. Thus any new diagnostic tests must undergo a thorough evaluation. New diagnostic tests are evaluated in comparison with the respective gold standard tests. The performance of binary…

应用统计 · 统计学 2025-09-17 Wan Nor Arifin , Umi Kalsom Yusof

In diagnostic studies, researchers frequently encounter imperfect reference standards with some misclassified labels. Treating these as gold standards can bias receiver operating characteristic (ROC) curve analysis. To address this issue,…

统计方法学 · 统计学 2025-02-13 Yifan Sun , Peijun Sang , Qinglong Tian , Pengfei Li

In pandemics or epidemics, public health authorities need to rapidly test a large number of individuals, both to determine the line of treatment as well as to know the spread of infection to plan containment, mitigation and future…

其他定量生物学 · 定量生物学 2020-03-31 Tarun Jain , Bijendra Nath Jain

Group testing enables the identification of a small subset of defective items within a larger population by performing tests on pools of items rather than on each item individually. Over the years, it has not only attracted attention from…

信息论 · 计算机科学 2026-01-13 Manuel Franco-Vivo

The corona virus disease 2019 (COVID-19) caused by the novel corona virus has an exponential rate of infection. COVID-19 is particularly notorious as the onset of symptoms in infected patients are usually delayed and there exists a large…

统计方法学 · 统计学 2020-04-16 Lakshmi N. Theagarajan

We present a parameter estimation technique based on performing joint measurements of a weak interaction away from the weak-value-amplification approximation. Two detectors are used to collect full statistics of the correlations between two…

量子物理 · 物理学 2016-03-11 Julián Martínez-Rincón , Wei-Tao Liu , Gerardo I. Viza , John C. Howell

Adapting pre-trained models to new tasks can exhibit varying effectiveness across datasets. Visual prompting, a state-of-the-art parameter-efficient transfer learning method, can significantly improve the performance of out-of-distribution…

计算机视觉与模式识别 · 计算机科学 2024-09-05 Hsi-Ai Tsao , Lei Hsiung , Pin-Yu Chen , Tsung-Yi Ho

The phase locking value (PLV) is a widely used measure to detect phase connectivity. Main drawbacks of the standard PLV are it can be sensitive to noisy observations and does not provide uncertainty measures under finite samples. To…

统计方法学 · 统计学 2025-09-09 Shonosuke Sugasawa , Takeru Matsuda , Tomoyuki Nagakawa

Labeling patients in electronic health records with respect to their statuses of having a disease or condition, i.e. case or control statuses, has increasingly relied on prediction models using high-dimensional variables derived from…

统计方法学 · 统计学 2021-10-14 Zijian Guo , Prabrisha Rakshit , Daniel S. Herman , Jinbo Chen

Pooling specimens, a well-accepted sampling strategy in biomedical research, can be applied to reduce the cost of studying biomarkers. Even if the cost of a single assay is not a major restriction in evaluating biomarkers, pooling can be a…

应用统计 · 统计学 2012-03-01 Enrique F. Schisterman , Albert Vexler , Aijun Ye , Neil J. Perkins

Linear principal component analysis (PCA) can be extended to a nonlinear PCA by using artificial neural networks. But the benefit of curved components requires a careful control of the model complexity. Moreover, standard techniques for…

机器学习 · 计算机科学 2012-04-04 Matthias Scholz

Existing Partial Label Learning (PLL) methods posit that training and test data adhere to the same distribution, a premise that frequently does not hold in practical application where Out-of-Distribution (OOD) objects are present. We…

计算机视觉与模式识别 · 计算机科学 2025-03-13 Jintao Huang , Yiu-Ming Cheung , Chi-Man Vong

Viral load (VL) in the respiratory tract is the leading proxy for assessing infectiousness potential. Understanding the dynamics of disease-related VL within the host is very important and help to determine different policy and health…

应用统计 · 统计学 2023-08-21 Yonatan Woodbridge , Micha Mandel , Yair Goldberg , Amit Huppert

A Pulse-Compression Probing (PCP) method is applied in time-domain to identify an equivalent circuit model of a distribution network as seen from the transmission grid. A Pseudo-Random Binary Pulse Train (PRBPT) is injected as a voltage…

系统与控制 · 电气工程与系统科学 2023-06-05 Nicholas Piaquadio , N. Eva Wu , Morteza Sarailoo , Jianzhuang Huang

The propensity score is widely used for causal inference in observational studies, but common parametric estimators can produce biased and inefficient effect estimates when model assumptions are violated. Nonparametric approaches reduce…

统计方法学 · 统计学 2026-04-09 Maosen Peng , Yan Li , Chong Wu , Liang Li

Pooled testing is widely used for screening for viral or bacterial infections with low prevalence when individual testing is not cost-efficient. Pooled testing with qualitative assays that give binary results has been well-studied. However,…

统计方法学 · 统计学 2020-11-03 Tao Liu , Joseph W Hogan , Wanning Su , Yizhen Xu , Michael J Daniels , Kantor Rami

We study adaptive pooling under predictive heterogeneity in high-dimensional multivariate time series forecasting, where global models improve statistical efficiency but may fail to capture heterogeneous predictive structure, while naive…

统计方法学 · 统计学 2026-04-16 Ziling Ma , Ángel López Oriona , Hernando Ombao , Ying Sun

Much recent work on visual recognition aims to scale up learning to massive, noisily-annotated datasets. We address the problem of scaling- up the evaluation of such models to large-scale datasets with noisy labels. Current protocols for…

计算机视觉与模式识别 · 计算机科学 2018-07-03 Phuc Nguyen , Deva Ramanan , Charless Fowlkes

We propose two-stage adaptive pooling schemes, 2-STAP and 2-STAMP, for detecting COVID-19 using real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR) test kits. Similar to the Tapestry scheme of Ghosh et al., the…

信息论 · 计算机科学 2020-07-07 Anoosheh Heidarzadeh , Krishna R. Narayanan