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Flow cytometry (FCM) is an analytic technique that is capable of detecting and recording the emission of fluorescence and light scattering of cells or particles (that are collectively called "events") in a population. A typical FCM…

定量方法 · 定量生物学 2020-11-20 Nathan Wong , Daehwan Kim , Zachery Robinson , Connie Huang , Irina M. Conboy

Accurate cell counting is essential in various biomedical research and clinical applications, including cancer diagnosis, stem cell research, and immunology. Manual counting is labor-intensive and error-prone, motivating automation through…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Abdurahman Ali Mohammed , Catherine Fonder , Ying Wei , Wallapak Tavanapong , Donald S Sakaguchi , Qi Li , Surya K. Mallapragada

Identifying cell types and subtypes in routine histopathology is fundamental for understanding disease. Existing tile-based models capture nuclear detail but miss the broader tissue context that influences cell identity. Current human…

计算机视觉与模式识别 · 计算机科学 2025-11-20 Yinuo Xu , Yan Cui , Mingyao Li , Zhi Huang

Fine-grained classification and counting of bone marrow erythroid cells are vital for evaluating the health status and formulating therapeutic schedules for leukemia or hematopathy. Due to the subtle visual differences between different…

计算机视觉与模式识别 · 计算机科学 2022-12-29 Ye Wang , Rui Ma , Xiaoqing Ma , Honghua Cui , Yubin Xiao , Xuan Wu , You Zhou

Red blood cells are highly deformable and present in various shapes. In blood cell disorders, only a subset of all cells is morphologically altered and relevant for the diagnosis. However, manually labeling of all cells is laborious,…

计算机视觉与模式识别 · 计算机科学 2020-07-24 Ario Sadafi , Asya Makhro , Anna Bogdanova , Nassir Navab , Tingying Peng , Shadi Albarqouni , Carsten Marr

Modern networks carry increasingly diverse and encrypted traffic types that demand classification techniques beyond traditional port-based and payload-based methods. This tutorial provides a practical, end-to-end guide to building…

网络与互联网体系结构 · 计算机科学 2026-01-08 Adrian Pekar , Richard Plny , Karel Hynek

4D-flow magnetic resonance imaging (MRI) is an emerging imaging technique where spatiotemporal 3D blood velocity can be captured with full volumetric coverage in a single non-invasive examination. This enables qualitative and quantitative…

图像与视频处理 · 电气工程与系统科学 2020-04-16 Edward Ferdian , Avan Suinesiaputra , David Dubowitz , Debbie Zhao , Alan Wang , Brett Cowan , Alistair Young

Explainability for Deep Learning Models is especially important for clinical applications, where decisions of automated systems have far-reaching consequences. While various post-hoc explainable methods, such as attention visualization and…

Diffusion-based unsupervised image registration has been explored for cardiac cine MR, but expensive multi-step inference limits practical use. We propose FlowReg, a flow-matching framework in displacement field space that achieves strong…

计算机视觉与模式识别 · 计算机科学 2026-03-04 Yunguan Fu , Wenjia Bai , Wen Yan , Matthew J Clarkson , Rhodri Huw Davies , Yipeng Hu

Acute Lymphoblastic Leukemia (ALL) is the most frequent hematologic malignancy in children and adolescents. A strong prognostic factor in ALL is given by the Minimal Residual Disease (MRD), which is a measure for the number of leukemic…

Flow cytometry is a cornerstone technique in medical and biological research, providing crucial information about cell size and granularity through forward scatter (FSC) and side scatter (SSC) signals. Despite its widespread use, the…

光学 · 物理学 2024-08-29 Jaepil Jo , Herve Hugonnet , Mahn Jae Lee , YongKeun Park

We propose a machine learning framework based on Flow Matching (FM) to identify critical properties in many-body systems efficiently. Using the 2D XY model as a benchmark, we demonstrate that a single network, trained only on configurations…

统计力学 · 物理学 2026-01-06 Qian-Rui Lee , Daw-Wei Wang

Colorectal diseases, including inflammatory conditions and neoplasms, require quick, accurate care to be effectively treated. Traditional diagnostic pipelines require extensive preparation and rely on separate, individual evaluations on…

计算机视觉与模式识别 · 计算机科学 2025-09-09 Krithik Ramesh , Ritvik Koneru

Tracking cells in time-lapse videos is an essential technique for monitoring cell population dynamics at a single-cell level. Current methods for cell tracking are developed on videos with mostly single, constant signals and do not detect…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Florian Bürger , Martim Dias Gomes , Nica Gutu , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

In addition to generating data and annotations, devising sensible data splitting strategies and evaluation metrics is essential for the creation of a benchmark dataset. This practice ensures consensus on the usage of the data, homogeneous…

计算机视觉与模式识别 · 计算机科学 2023-03-01 Chinedu Innocent Nwoye , Nicolas Padoy

Diffusion models can learn rich representations during data generation, showing potential for Self-Supervised Learning (SSL), but they face a trade-off between generative quality and discriminative performance. Their iterative sampling also…

机器学习 · 计算机科学 2025-12-24 Kosuke Ukita , Tsuyoshi Okita

In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…

计算机视觉与模式识别 · 计算机科学 2022-06-07 Shahira Abousamra , David Belinsky , John Van Arnam , Felicia Allard , Eric Yee , Rajarsi Gupta , Tahsin Kurc , Dimitris Samaras , Joel Saltz , Chao Chen

Critical clinical decision points in haematology are influenced by the requirement of bone marrow cytology for a haematological diagnosis. Bone marrow cytology, however, is restricted to reference facilities with expertise, and linked to…

图像与视频处理 · 电气工程与系统科学 2023-05-10 Raisa Fairooz Meem , Khandaker Tabin Hasan

Due to morphological similarity at the microscopic level, making an accurate and time-sensitive distinction between blood cells affected by Acute Lymphocytic Leukemia (ALL) and their healthy counterparts calls for the usage of machine…

计算机视觉与模式识别 · 计算机科学 2022-07-29 Sai Mattapalli , Rishi Athavale

Diagnosing diseases such as leukemia or anemia requires reliable counts of blood cells. Hematologists usually label and count microscopy images of blood cells manually. In many cases, however, cells in different maturity states are…

机器学习 · 计算机科学 2020-07-13 Yushan Liu , Markus M. Geipel , Christoph Tietz , Florian Buettner