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We consider a log-linear model for survival data, where both the location and scale parameters depend on covariates and the baseline hazard function is completely unspecified. This model provides the flexibility needed to capture many…

统计方法学 · 统计学 2019-01-16 Kevin Burke , Frank Eriksson , C. B. Pipper

A new method called SurvLIME for explaining machine learning survival models is proposed. It can be viewed as an extension or modification of the well-known method LIME. The main idea behind the proposed method is to apply the Cox…

机器学习 · 计算机科学 2020-03-19 Maxim S. Kovalev , Lev V. Utkin , Ernest M. Kasimov

Survival analysis is a critical tool for the modelling of time-to-event data, such as life expectancy after a cancer diagnosis or optimal maintenance scheduling for complex machinery. However, current neural network models provide an…

机器学习 · 统计学 2021-12-06 Fabio Luis de Mello , J Mark Wilkinson , Visakan Kadirkamanathan

Flexible continuous-time survival modeling is critical for capturing complex time-varying hazard dynamics in high-dimensional data; however, training such models remains challenging due to the intractable integral required for likelihood…

机器学习 · 统计学 2026-05-18 Chaeyeon Lee , Sehwan Kim , Hyungrok Do

Factorial analyses offer a powerful nonparametric means to detect main or interaction effects among multiple treatments. For survival outcomes, e.g. from clinical trials, such techniques can be adopted for comparing reasonable…

统计方法学 · 统计学 2023-02-06 Takeshi Emura , Marc Ditzhaus , Dennis Dobler , Kenta Murotani

Recurrent event analyses have found a wide range of applications in biomedicine, public health, and engineering, among others, where study subjects may experience a sequence of event of interest during follow-up. The R package reReg (Chiou…

统计计算 · 统计学 2022-08-23 Sy Han Chiou , Gongjun Xu , Jun Yan , Chiung-Yu Huang

Applications of machine learning in healthcare often require working with time-to-event prediction tasks including prognostication of an adverse event, re-hospitalization or death. Such outcomes are typically subject to censoring due to…

机器学习 · 计算机科学 2022-08-04 Chirag Nagpal , Willa Potosnak , Artur Dubrawski

In many biomedical applications, outcome is measured as a ``time-to-event'' (eg. disease progression or death). To assess the connection between features of a patient and this outcome, it is common to assume a proportional hazards model,…

统计理论 · 数学 2020-08-11 Aliasghar Tarkhan , Noah Simon

The distribution-free method of conformal prediction (Vovk et al, 2005) has gained considerable attention in computer science, machine learning, and statistics. Candes et al. (2023) extended this method to right-censored survival data,…

统计方法学 · 统计学 2025-06-04 Jing Qin , Jin Piao , Jing Ning , Yu Shen

Accurate survival prediction is critical in oncology for prognosis and treatment planning. Traditional approaches often rely on a single data modality, limiting their ability to capture the complexity of tumor biology. To address this…

机器学习 · 计算机科学 2025-07-11 Alba Garrido , Alejandro Almodóvar , Patricia A. Apellániz , Juan Parras , Santiago Zazo

Monitoring the quality of statistical processes has been of great importance, mostly in industrial applications. Control charts are widely used for this purpose, but often lack the possibility to monitor survival outcomes. Recently,…

应用统计 · 统计学 2024-06-19 Daniel Gomon , Marta Fiocco , Hein Putter , Mirko Signorelli

The Cox proportional hazards model is often used to analyze data from Randomized Controlled Trials (RCT) with time-to-event outcomes. Random survival forest (RSF) is a machine-learning algorithm known for its high predictive performance. We…

机器学习 · 统计学 2025-05-28 Ricarda Graf , Susan Todd , M. Fazil Baksh

Time-to-event data is widespread across the life sciences and engineering, but it is typically encountered together with censoring, which complicates the application of standard machine learning methods. Deep Cox models have emerged as a…

机器学习 · 统计学 2026-05-19 Anchit Jain , Kevin Zhang , Stephen Bates

Background: The development of classification methods for personalized medicine is highly dependent on the identification of predictive genetic markers. In survival analysis it is often necessary to discriminate between influential and…

统计方法学 · 统计学 2018-02-27 Thomas Welchowski , Verena Zuber , Matthias Schmid

In survival analysis, longitudinal information on the health status of a patient can be used to dynamically update the predicted probability that a patient will experience an event of interest. Traditional approaches to dynamic prediction…

统计方法学 · 统计学 2025-06-16 Mirko Signorelli

Covariate adjustment aims to improve the statistical efficiency of randomized trials by incorporating information from baseline covariates. Popular methods for covariate adjustment include analysis of covariance for continuous endpoints and…

统计方法学 · 统计学 2025-05-09 Zhiwei Zhang , Ya Wang , Dong Xi

Ranked set sampling (RSS) is a cost-efficient study design that uses inexpensive baseline ranking to select a more informative subset of individuals for full measurement. While RSS is well known to improve precision over simple random…

统计方法学 · 统计学 2025-12-30 Nabil Awan , Richard J. Chappell

Survival regression is widely used to model time-to-events data, to explore how covariates may influence the occurrence of events. Modern datasets often encompass a vast number of covariates across many subjects, with only a subset of the…

统计方法学 · 统计学 2024-09-18 Abhishek Mandal , Abhisek Chakraborty

Survival analysis models the distribution of time until an event of interest, such as discharge from the hospital or admission to the ICU. When a model's predicted number of events within any time interval is similar to the observed number,…

机器学习 · 计算机科学 2021-01-15 Mark Goldstein , Xintian Han , Aahlad Puli , Adler J. Perotte , Rajesh Ranganath

Health economic evaluations often require predictions of survival rates beyond the follow-up period. Parametric survival models can be more convenient for economic modelling than the Cox model. The generalized gamma (GG) and generalized F…

统计计算 · 统计学 2022-07-13 Han Fu , Shahrul Mt-Isa , Richard Baumgartner , William Malbecq