相关论文: Survival Analysis of Young Triple-Negative Breast …
Breast cancer is a significant public health concern and is the leading cause of cancer-related deaths among women. Despite advances in breast cancer treatments, medication non-adherence remains a major problem. As electronic health records…
Lung cancer is the primary cause of cancer-related mortality, claiming approximately 1.79 million lives globally in 2020, with an estimated 2.21 million new cases diagnosed within the same period. Among these, Non-Small Cell Lung Cancer…
Early screening for cancer has proven to improve the survival rate and spare patients from intensive and costly treatments due to late diagnosis. Cancer screening in the healthy population involves an initial risk stratification step to…
Despite the fact that cancer survivability rates vary greatly between stages, traditional survival prediction models have frequently been trained and assessed using examples from all combined phases of the disease. This method may result in…
We developed and validated TRisk, a Transformer-based AI model predicting 36-month mortality in heart failure patients by analysing temporal patient journeys from UK electronic health records (EHR). Our study included 403,534 heart failure…
Multi-gene panel testing allows many cancer susceptibility genes to be tested quickly at a lower cost making such testing accessible to a broader population. Thus, more patients carrying pathogenic germline mutations in various…
To explain a bimodal pattern of hazard of relapse among early stage breast cancer patients identified in multiple databases, we proposed that late relapses result from steady stochastic progressions from single dormant malignant cells to…
Cancer is one of the most feared diseases in the world it has increased disturbingly and breast cancer occurs in one out of eight women, the prediction of malignancies plays essential roles not only in revealing human genome, but also in…
In this article, we particularly address the problem of assessing the impact of clinical stage and age on the specific survival times of men with breast cancer when cure is a possibility, where there is also the interest of explaining this…
Breast cancer is a major global health issue that affects millions of women worldwide. Classification of breast cancer as early and accurately as possible is crucial for effective treatment and enhanced patient outcomes. Deep transfer…
Background Predicting overall survival (OS) in non-small cell lung cancer (NSCLC) is essential for clinical decision-making and drug development. While tumor and blood test markers kinetics are intrinsically linked, their joint dynamics and…
Despite significant research efforts and advancements, cancer remains a leading cause of mortality. Early cancer prediction has become a crucial focus in cancer research to streamline patient care and improve treatment outcomes. Manual…
In cancer epidemiology using population-based data, regression models for the excess mortality hazard is a useful method to estimate cancer survival and to describe the association between prognosis factors and excess mortality. This method…
Individual cancer cells carry a bewildering number of distinct genomic alterations i.e., copy number variations and mutations, making it a challenge to uncover genomic-driven mechanisms governing tumorigenesis. Here we performed…
Tongue cancer is a common oral cavity malignancy that originates in the mouth and throat. Much effort has been invested in improving its diagnosis, treatment, and management. Surgical removal, chemotherapy, and radiation therapy remain the…
Breast cancer is one of the leading causes of cancer mortality. Breast cancer patients in developing countries, especially sub-Saharan Africa, South Asia, and South America, suffer from the highest mortality rate in the world. One crucial…
Notorious for its 70-80% recurrence rate, Non-muscle-invasive Bladder Cancer (NMIBC) imposes a significant human burden and is one of the costliest cancers to manage. Current tools for predicting NMIBC recurrence rely on scoring systems…
Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…
Biological age, which may be older or younger than chronological age due to factors such as genetic predisposition, environmental exposures, serves as a meaningful biomarker of aging processes and can inform risk stratification, treatment…
Background and Objective: Only about 14 % of eligible EU citizens finally participate in colorectal cancer (CRC) screening programs despite it being the third most common type of cancer worldwide. The development of CRC risk models can…