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We consider estimation of a functional parameter of a realistically modeled data distribution based on observing independent and identically distributed observations. We define an $m$-th order Spline Highly Adaptive Lasso Minimum Loss…

统计理论 · 数学 2021-07-05 Mark J. van der Laan , David Benkeser , Weixin Cai

The Highly-Adaptive-Lasso(HAL)-TMLE is an efficient estimator of a pathwise differentiable parameter in a statistical model that at minimal (and possibly only) assumes that the sectional variation norm of the true nuisance parameters are…

统计理论 · 数学 2017-09-01 Mark van der Laan

Consider the case that we observe $n$ independent and identically distributed copies of a random variable with a probability distribution known to be an element of a specified statistical model. We are interested in estimating an infinite…

统计理论 · 数学 2017-09-20 Mark J. van der Laan , Aurélien F. Bibaut

We propose a novel, fully nonparametric approach for the multi-task learning, the Multi-task Highly Adaptive Lasso (MT-HAL). MT-HAL simultaneously learns features, samples and task associations important for the common model, while imposing…

Asymptotic efficiency of targeted maximum likelihood estimators (TMLE) of target features of the data distribution relies on a a second order remainder being asymptotically negligible. In previous work we proposed a nonparametric MLE termed…

统计理论 · 数学 2021-07-02 Mark van der Laan , Zeyi Wang , Lars van der Laan

The Highly-Adaptive-LASSO Targeted Minimum Loss Estimator (HAL-TMLE) is an efficient plug-in estimator of a pathwise differentiable parameter in a statistical model that at minimal (and possibly only) assumes that the sectional variation…

统计理论 · 数学 2020-02-12 Weixin Cai , Mark van der Laan

We address the challenge of performing Targeted Maximum Likelihood Estimation (TMLE) after an initial Highly Adaptive Lasso (HAL) fit. Existing approaches that utilize the data-adaptive working model selected by HAL-such as the relaxed HAL…

统计方法学 · 统计学 2025-06-23 Yi Li , Sky Qiu , Zeyi Wang , Mark van der Laan

Estimating the conditional mean function is a central task in statistical learning. In this paper, we consider estimation and inference for a nonparametric class of real-valued cadlag functions with bounded sectional variation (Gill et al.,…

统计方法学 · 统计学 2025-10-17 Wenxin Zhang , Junming Shi , Alan Hubbard , Mark van der Laan

Accumulated Local Effect (ALE) is a method for accurately estimating feature effects, overcoming fundamental failure modes of previously-existed methods, such as Partial Dependence Plots. However, ALE's approximation, i.e. the method for…

机器学习 · 计算机科学 2022-10-11 Vasilis Gkolemis , Theodore Dalamagas , Christos Diou

Structured Latent Attribute Models (SLAMs) are a family of discrete latent variable models widely used in education, psychology, and epidemiology to model multivariate categorical data. A SLAM assumes that multiple discrete latent…

统计方法学 · 统计学 2021-07-12 Yuqi Gu , Gongjun Xu

We investigate the finite sample performance of sample splitting, cross-fitting and averaging for the estimation of the conditional average treatment effect. Recently proposed methods, so-called meta-learners, make use of machine learning…

统计方法学 · 统计学 2020-08-27 Daniel Jacob

We consider estimation of a functional of the data distribution based on i.i.d. observations. We assume the target function can be defined as the minimizer of the expectation of a loss function over a class of $d$-variate real valued cadlag…

统计理论 · 数学 2023-02-01 Mark van der Laan

Empirical risk minimization (ERM) with a computationally feasible surrogate loss is a widely accepted approach for classification. Notably, the convexity and calibration (CC) properties of a loss function ensure consistency of ERM in…

机器学习 · 统计学 2024-09-05 Ben Dai

Imbalanced learning (IL), i.e., learning unbiased models from class-imbalanced data, is a challenging problem. Typical IL methods including resampling and reweighting were designed based on some heuristic assumptions. They often suffer from…

机器学习 · 计算机科学 2020-10-20 Zhining Liu , Pengfei Wei , Jing Jiang , Wei Cao , Jiang Bian , Yi Chang

Hyperparameters tuning and model selection are important steps in machine learning. Unfortunately, classical hyperparameter calibration and model selection procedures are sensitive to outliers and heavy-tailed data. In this work, we…

统计理论 · 数学 2019-05-22 Joon Kwon , Guillaume Lecué , Matthieu Lerasle

Debiased machine learning estimators for smooth functionals in nonparametric models can exhibit substantial variability and instability, often leading practitioners to instead rely on parametric or semiparametric working models. Such…

统计方法学 · 统计学 2026-03-20 Lars van der Laan , Marco Carone , Alex Luedtke , Mark van der Laan

Meta-learning synthesizes and leverages the knowledge from a given set of tasks to rapidly learn new tasks using very little data. Meta-learning of linear regression tasks, where the regressors lie in a low-dimensional subspace, is an…

机器学习 · 计算机科学 2021-05-19 Kiran Koshy Thekumparampil , Prateek Jain , Praneeth Netrapalli , Sewoong Oh

Estimating model parameters is a crucial step in mathematical modelling and typically involves minimizing the disagreement between model predictions and experimental data. This calibration data can change throughout a study, particularly if…

定量方法 · 定量生物学 2023-11-03 Tyler Cassidy

Estimation of heterogeneous long-term treatment effects (HLTEs) is widely used for personalized decision-making in marketing, economics, and medicine, where short-term randomized experiments are often combined with long-term observational…

机器学习 · 计算机科学 2026-04-02 Haorui Ma , Dennis Frauen , Valentyn Melnychuk , Stefan Feuerriegel

Multi-distribution learning (MDL), which seeks to learn a shared model that minimizes the worst-case risk across $k$ distinct data distributions, has emerged as a unified framework in response to the evolving demand for robustness,…

机器学习 · 计算机科学 2025-08-12 Zihan Zhang , Wenhao Zhan , Yuxin Chen , Simon S. Du , Jason D. Lee
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