相关论文: Building rigid networks with prestress and selecti…

The dynamic response of prestressed semiflexible biopolymers is characterized by the propagation and relaxation of tension, which arises due to the near inextensibility of a stiff backbone. It is coupled to the dynamics of contour length…

Branched actin networks exert pushing forces in eukaryotic cells, and adapt their stiffness to their environment. The physical basis for their mechanics and adaptability is however not understood. Indeed, here we show that their high…

Since the invention of polymer networks in the 19th century (e.g., crosslinked natural rubber by Goodyear), it has been a dogma that stiffer networks are less stretchable, a trade-off inherent to the molecular nature of polymer network…

Recurrent neural networks are frequently studied in terms of their information-processing capabilities. The structural properties of these networks are seldom considered, beyond those emerging from the connectivity tuning necessary for…

Geometric and structural constraints greatly restrict the selection of folds adapted by protein backbones, and yet, folded proteins show an astounding diversity in functionality. For structure to have any bearing on function, it is thus…

As deep neural networks grow in size, from thousands to millions to billions of weights, the performance of those networks becomes limited by our ability to accurately train them. A common naive question arises: if we have a system with…

In this research study, a numerical tool, which is based on a version of Slender Body theory, has been used and also modified to simulate the mechanical behaviour of single- and double-cross-linked biopolymer networks (hydrogel) under…

The mechanical properties of cells are dominated by the cytoskeleton, an interconnected network of long elastic filaments. The connections between the filaments are provided by crosslinking proteins, which constitute, next to the filaments,…

Networks and dense suspensions frequently reside near a boundary between soft (or fluid-like) and rigid (or solid-like) regimes. Transitions between these regimes can be driven by changes in structure, density, or applied stress or strain.…

Semiflexible biopolymer networks are commonly found in biological systems, from the cytoskeleton of cells to the extracellular matrix. Such networks often naturally occur as composites, in which various components interact to generate rich…

Artificial neural networks took a lot of inspiration from their biological counterparts in becoming our best machine perceptual systems. This work summarizes some of that history and incorporates modern theoretical neuroscience into…

Force transmission at large length scales is crucial for such biological functions as cell motility and morphogenesis. The networks that transmit these forces are malleable, patterned by active forces generated at the microscale by…

Pruning neural networks has regained interest in recent years as a means to compress state-of-the-art deep neural networks and enable their deployment on resource-constrained devices. In this paper, we propose a robust compressive learning…

Modern deep networks have millions to billions of parameters, which leads to high memory and energy requirements during training as well as during inference on resource-constrained edge devices. Consequently, pruning techniques have been…

There has recently been an increasing desire to evaluate neural networks locally on computationally-limited devices in order to exploit their recent effectiveness for several applications; such effectiveness has nevertheless come together…

Recurrent neural networks (RNNs) have recently achieved remarkable successes in a number of applications. However, the huge sizes and computational burden of these models make it difficult for their deployment on edge devices. A practically…

Recent studies assessing the efficacy of pruning neural networks methods uncovered a surprising finding: when conducting ablation studies on existing pruning-at-initialization methods, namely SNIP, GraSP, SynFlow, and magnitude pruning,…

Due to their unique structural and mechanical properties, randomly-crosslinked polymer networks play an important role in many different fields, ranging from cellular biology to industrial processes. In order to elucidate how these…

Transient networks comprised of polymers connected by short-lived bonds are a common design theme for both biological and synthetic materials. Transient bonds can provide mechanical rigidity, while still allowing for visco-elastic flows on…

Deep neural networks have achieved increasingly accurate results on a wide variety of complex tasks. However, much of this improvement is due to the growing use and availability of computational resources (e.g use of GPUs, more layers, more…