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This paper studies quantum optimization baselines for the Generalized Traveling Salesman Problem (GTSP), a clustered routing problem that naturally models variant selection and sequencing problems under discrete alternatives. We propose a…

As DNA data storage moves closer to practical deployment, minimizing sequencing coverage depth is essential to reduce both operational costs and retrieval latency. This paper addresses the recently studied Random Access Problem, which…

信息论 · 计算机科学 2026-01-13 Chen Wang , Eitan Yaakobi

Early hardware limitations of GPU (lack of synchronization primitives and limited memory caching mechanisms) can make GPU-based computation inefficient. Now Bio-technologies bring more chances to Bioinformatics and Biological Engineering.…

分布式、并行与集群计算 · 计算机科学 2014-10-29 YuKun Zhong , BaoQiu Wang , JianBiao Lin , Chen Tao , Che Nian , Xie Wen

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…

其他定量生物学 · 定量生物学 2014-03-12 Jian-Jun Shu , Li Shan Ouw

Quantum Approximate Optimization Algorithm (QAOA) is a hybrid classical-quantum algorithm to approximately solve NP optimization problems such as MAX-CUT. We describe a new application area of QAOA circuits: graph structure discovery. We…

量子物理 · 物理学 2020-01-01 Mario Szegedy

We propose a genetic algorithm (GA) for hyperparameter optimization of artificial neural networks which includes chromosomal crossover as well as a decoupling of parameters (i.e., weights and biases) from hyperparameters (e.g., learning…

神经与进化计算 · 计算机科学 2019-01-15 Aaron Vose , Jacob Balma , Alex Heye , Alessandro Rigazzi , Charles Siegel , Diana Moise , Benjamin Robbins , Rangan Sukumar

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of…

软凝聚态物质 · 物理学 2015-06-25 Johan Lagerqvist , Michael Zwolak , Massimiliano Di Ventra

Next-generation sequencing technologies provide a revolutionary tool for generating gene expression data. Starting with a fixed RNA sample, they construct a library of millions of differentially abundant short sequence tags or "reads",…

定量方法 · 定量生物学 2014-05-13 Dimitrios V. Vavoulis , Julian Gough

The quantum approximate optimization algorithm (QAOA) is one of the most promising candidates for achieving quantum advantage through quantum-enhanced combinatorial optimization. Optimal QAOA parameter concentration effects for special…

量子物理 · 物理学 2024-07-10 Jose Falla , Quinn Langfitt , Yuri Alexeev , Ilya Safro

Significant research has been carried out recently to find the optimal path in network routing. Among them, the evolutionary algorithm approach is an area where work is carried out extensively. We in this paper have used particle swarm…

网络与互联网体系结构 · 计算机科学 2014-07-22 Kavitha Sooda , T. R. Gopalakrishnan Nair

The growing variety of quantum hardware technologies, each with unique peculiarities such as connectivity and native gate sets, creates challenges when selecting the best platform for executing a specific quantum circuit. This selection…

量子物理 · 物理学 2026-01-29 Antonio Tudisco , Deborah Volpe , Giacomo Orlandi , Giovanna Turvani

Statistical analysis of DNA mixtures is known to pose computational challenges due to the enormous state space of possible DNA profiles. We propose a Bayesian network representation for genotypes, allowing computations to be performed…

统计方法学 · 统计学 2014-02-21 Therese Graversen , Steffen Lauritzen

The Quantum approximate optimization algorithm (QAOA) is one of the most promising candidates for achieving quantum advantage through quantum-enhanced combinatorial optimization. In a typical QAOA setup, a set of quantum circuit parameters…

量子物理 · 物理学 2021-06-15 Alexey Galda , Xiaoyuan Liu , Danylo Lykov , Yuri Alexeev , Ilya Safro

DNA sequencing allows for the determination of the genetic code of an organism, and therefore is an indispensable tool that has applications in Medicine, Life Sciences, Evolutionary Biology, Food Sciences and Technology, and Agriculture. In…

量子物理 · 物理学 2023-04-24 Nouhaila Innan , Muhammad Al-Zafar Khan

Quantum algorithms offer a compelling new avenue for addressing difficult NP-complete optimization problems, such as the Generalized Assignment Problem (GAP). Given the operational constraints of contemporary Noisy Intermediate-Scale…

量子物理 · 物理学 2025-11-05 Carlo Mastroianni , Francesco Plastina , Jacopo Settino , Andrea Vinci

Quantum adiabatic evolution provides a general technique for the solution of combinatorial search problems on quantum computers. We present the results of a numerical study of a particular application of quantum adiabatic evolution, the…

量子物理 · 物理学 2018-12-20 Andrew M. Childs , Edward Farhi , Jeffrey Goldstone , Sam Gutmann

Establishing quantum advantage for variational quantum algorithms is an important direction in quantum computing. In this work, we apply the Quantum Approximate Optimisation Algorithm (QAOA) -- a popular variational quantum algorithm for…

量子物理 · 物理学 2024-01-08 Andrew El-Kadi , Roberto Bondesan

We present a family of \textit{Gaussian Mixture Approximation} (GMA) samplers for sampling unnormalised target densities, encompassing \textit{weights-only GMA} (W-GMA), \textit{Laplace Mixture Approximation} (LMA),…

机器学习 · 计算机科学 2025-10-01 Yongchao Huang

Traditional stereo matching algorithms like Semi-Global Block Matching (SGBM) with Weighted Least Squares (WLS) filtering offer speed advantages over neural networks for UAV applications, generating disparity maps in approximately 0.5…

计算机视觉与模式识别 · 计算机科学 2025-12-08 Yida Lin , Bing Xue , Mengjie Zhang , Sam Schofield , Richard Green
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