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Cardiovascular diseases stand as the primary global cause of mortality. Among the various imaging techniques available for visualising the heart and evaluating its function, echocardiograms emerge as the preferred choice due to their safety…

图像与视频处理 · 电气工程与系统科学 2023-11-22 Adil Dahlan , Cyril Zakka , Abhinav Kumar , Laura Tang , Rohan Shad , Robyn Fong , William Hiesinger

Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate AS, one with a dilated…

流体动力学 · 物理学 2022-12-13 Hadi Zolfaghari , Mervyn Andiapen , Andreas Baumbach , Anthony Mathur , Rich R. Kerswell

In the last ten years, medical robotics has moved from the margins to the mainstream. Since the Engineering Research Center for Computer-Integrated Surgical Systems and Technology was Launched in 1998 with National Science Foundation…

CAD remains a major global public health burden, yet scalable screening tools are limited. Although CCTA is a first-line non-invasive diagnostic modality, its use is constrained by resource requirements and radiation exposure. AI-ECG may…

We perform various numerical tests to study the effect of (boundary) stenosis on blood flow stability, employing a detailed and accurate, second-order finite-volume scheme for numerically implementing a partial differential equation (PDE)…

数值分析 · 数学 2024-08-05 Shantanu Singh , Nikolaos Bekiaris-Liberis

The evaluation of obstructions (stenosis) in coronary arteries is currently done by a physician's visual assessment of coronary angiography video sequences. It is laborious, and can be susceptible to interobserver variation. Prior studies…

图像与视频处理 · 电气工程与系统科学 2021-02-01 Chengyang Zhou , Thao Vy Dinh , Heyi Kong , Jonathan Yap , Khung Keong Yeo , Hwee Kuan Lee , Kaicheng Liang

Stroke is the second leading cause of mortality worldwide. Immediate attention and diagnosis play a crucial role regarding patient prognosis. The key to diagnosis consists in localizing and delineating brain lesions. Standard stroke…

图像与视频处理 · 电气工程与系统科学 2024-09-05 Santiago Gómez , Daniel Mantilla , Gustavo Garzón , Edgar Rangel , Andrés Ortiz , Franklin Sierra-Jerez , Fabio Martínez

Central Serous Retinopathy (CSR) or Central Serous Chorioretinopathy (CSC) is a significant disease that causes blindness and vision loss among millions of people worldwide. It transpires as a result of accumulation of watery fluids behind…

图像与视频处理 · 电气工程与系统科学 2021-08-27 Syed Ale Hassan , Shahzad Akbar , Amjad Rehman , Tanzila Saba , Hoshang Kolivand , Saeed Ali Bahaj

Aortic valve (AV) biomechanics play a critical role in maintaining normal cardiac function. Pathological variations, particularly in bicuspid aortic valves, alter leaflet loading, increase strain, and accelerate disease progression.…

Kidney stone disease poses a major burden to patients and healthcare systems around the world. The formation of kidney stones may occur over months or years, but many patients are diagnosed at a late stage, suffer excruciating pain, and…

组织与器官 · 定量生物学 2023-09-01 Vincent Blay , Felix Grases

Providing closed and well-connected boundaries of coronary artery is essential to assist cardiologists in the diagnosis of coronary artery disease (CAD). Recently, several deep learning-based methods have been proposed for boundary…

In stable coronary artery disease (CAD), reduction in mortality and/or myocardial infarction with revascularization over medical therapy has not been reliably achieved. Coronary arteries are usually extracted to perform stenosis detection.…

图像与视频处理 · 电气工程与系统科学 2021-01-26 Chen Zhao , Haipeng Tang , Daniel McGonigle , Zhuo He , Chaoyang Zhang , Yu-Ping Wang , Hong-Wen Deng , Robert Bober , Weihua Zhou

Atrial fibrillation (AF) is a leading cause of morbidity and mortality. AF prevalence increases with age, which is attributed to pathophysiological changes that aid AF initiation and perpetuation. Current state-of-the-art models are only…

组织与器官 · 定量生物学 2015-10-05 Julie Eatock , Yen Ting Lin , Eugene T. Y. Chang , Tobias Galla , Richard H. Clayton

Cardiovascular disease, the leading cause of death globally, is an age-related disease. Understanding the morphological and functional changes of the heart during ageing is a key scientific question, the answer to which will help us define…

图像与视频处理 · 电气工程与系统科学 2022-10-11 Mengyun Qiao , Berke Doga Basaran , Huaqi Qiu , Shuo Wang , Yi Guo , Yuanyuan Wang , Paul M. Matthews , Daniel Rueckert , Wenjia Bai

Cardiovascular disease is the leading global cause of mortality, with coronary artery disease (CAD) as its most prevalent form, necessitating early risk prediction. While 3D coronary artery digital twins reconstructed from imaging offer…

With more than 60,000 deaths annually in the United States, Pulmonary Embolism (PE) is among the most fatal cardiovascular diseases. It is caused by an artery blockage in the lung; confirming its presence is time-consuming and is prone to…

图像与视频处理 · 电气工程与系统科学 2021-07-14 Sudhir Suman , Gagandeep Singh , Nicole Sakla , Rishabh Gattu , Jeremy Green , Tej Phatak , Dimitris Samaras , Prateek Prasanna

Complex coronary bifurcation lesions remain challenging in percutaneous coronary intervention, with stent design and deployment strategy influencing clinical outcomes. This study compares the mechanical and hemodynamic performance of the…

Aortic stenosis (AS) is a degenerative valve condition that causes substantial morbidity and mortality. This condition is under-diagnosed and under-treated. In clinical practice, AS is diagnosed with expert review of transthoracic…

图像与视频处理 · 电气工程与系统科学 2024-04-08 Zhe Huang , Benjamin S. Wessler , Michael C. Hughes

Myocardial infarction causes myocardium thinning, fibrosis, and progressive heart failure. Engineered human myocardium (EHM) is tested clinically as a first-in-class product for sustainable remuscularization in patients with advanced heart…

医学物理 · 物理学 2025-08-28 Hossein Goodarzi Hosseinabadi

The aorta is the body's largest arterial vessel, serving as the primary pathway for oxygenated blood within the systemic circulation. Aortic aneurysms consistently rank among the top twenty causes of mortality in the United States. Thoracic…

图像与视频处理 · 电气工程与系统科学 2025-09-17 Jiasong Chen , Linchen Qian , Ruonan Gong , Christina Sun , Tongran Qin , Thuy Pham , Caitlin Martin , Mohammad Zafar , John Elefteriades , Wei Sun , Liang Liang