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The flow behavior of blood in microvessels is directly associated with tissue perfusion and oxygen delivery. Current efforts on modeling blood flow have primarily focused on the flow properties of blood with red blood cells (RBCs) having a…

软凝聚态物质 · 物理学 2024-06-03 Wei Chien , Gerhard Gompper , Dmitry A. Fedosov

We investigate a set of design principles that link specific features of interparticle interactions to predictable structural and dynamic outcomes in two-dimensional self-assembly, a framework relevant to soft matter and biological…

软凝聚态物质 · 物理学 2026-01-06 Cecilia Bores , Antonio Diaz-Pozuelo , Enrique Lomba

Flowing blood displays a phenomenon called margination, in which leukocytes and platelets are preferentially found near blood vessel walls, while erythrocytes are depleted from these regions. Here margination is investigated using direct…

软凝聚态物质 · 物理学 2012-09-05 Amit Kumar , Michael D. Graham

Open cellular solids usually possess random microstructures that may contain a characteristic length scale, such as the cell size. This gives rise to size dependent mechanical properties where large systems behave differently from small…

材料科学 · 物理学 2018-01-03 Stefan Liebenstein , Stefan Sandfeld , Michael Zaiser

We introduce a mathematical model for the mechanical behaviour of the eukaryotic cell cytoskeleton. This discrete model involves a regular array of pre-stressed protein filaments that exhibit resistance to enthalpic stretching, joined at…

定量方法 · 定量生物学 2023-09-06 J. Köry , N. A. Hill , X. Y. Luo , P. S. Stewart

The short-range attraction and long-range repulsion (SALR) between nanoparticles or macromolecules can lead to spontaneous pattern formation on solid surfaces, fluid interfaces or membranes. In order to study the self-assembly in such…

软凝聚态物质 · 物理学 2014-01-07 J. Pekalski , A. Ciach , N. Almarza

The growth of laminar-turbulent band patterns in plane Couette flow is studied in the vicinity of the global stability threshold R_g below which laminar flow ultimately prevails. Appropriately tailored direct numerical simulations are…

流体动力学 · 物理学 2015-06-04 Paul Manneville

A slender thread of elastic hydrogel is susceptible to a surface instability that is reminiscent of the classical Rayleigh-Plateau instability of liquid jets. The final, highly nonlinear states that are observed in experiments arise from a…

软凝聚态物质 · 物理学 2020-12-16 Anupam Pandey , Minkush Kansal , Miguel A. Herrada , Jens Eggers , Jacco H. Snoeijer

In many physical situations involving diverse length scales, waves or rays representing them travel through media characterized by spatially smooth, random, modest refactive index variations. "Primary" diffraction (by individual…

经典物理 · 物理学 2021-12-14 Eric J Heller , Ragnar Fleischmann , Tobias Kramer

We present a tube model for the Brownian dynamics of associating polymers in extensional flow. In linear response, the model confirms the analytical predictions for the sticky diffusivity by Leibler- Rubinstein-Colby theory. Although a…

软凝聚态物质 · 物理学 2021-02-10 Charley Schaefer , Tom C. B. McLeish

We theoretically study the transport properties of self-propelled particles on complex structures, such as motor proteins on filament networks. A general master equation formalism is developed to investigate the persistent motion of…

软凝聚态物质 · 物理学 2014-09-19 M. Reza Shaebani , Zeinab Sadjadi , Igor M. Sokolov , Heiko Rieger , Ludger Santen

Colloidal particles of two types, driven in opposite directions, can segregate into lanes [Vissers et al. Soft Matter 7, 2352 (2011)]. This phenomenon can be reproduced by two-dimensional Brownian dynamics simulations of model particles…

统计力学 · 物理学 2016-08-31 Katherine Klymko , Phillip L. Geissler , Stephen Whitelam

We investigated the Rayleigh-Plateau instability at the interface between two immiscible liquids of equal viscosity using molecular dynamics simulations. Two types of initial conditions were considered, one with an imposed single-mode…

软凝聚态物质 · 物理学 2025-12-02 Shunta Kikuchi , Hiroshi Watanabe

A Rayleigh B\'enard instability study using the energy conserving dissipative particle dynamics method is presented here for the first time. The simulation is performed on an ideal dissipative particle dynamics fluid in a three dimensional…

统计力学 · 物理学 2012-01-19 Anuj Chaudhri , Jennifer R. Lukes

Red blood cells (RBCs) are responsible for transporting oxygen and various metabolites to tissues and organs, as well as removing waste. Several cardiovascular diseases can impair these functions. For instance, in diabetes, increased RBC…

生物物理 · 物理学 2025-01-08 Mehdi Abbasi , Chaouqi Misbah

We consider a cellular monolayer, described using a vertex-based model, for which cells form a spatially disordered array of convex polygons that tile the plane. Equilibrium cell configurations are assumed to minimize a global energy…

细胞行为 · 定量生物学 2018-05-30 Alexander Nestor-Bergmann , Emma Johns , Sarah Woolner , Oliver E. Jensen

Using Monte Carlo simulations, we investigate how geometric percolation and electrical conductivity in suspensions of hard conducting platelets are affected by the addition of platelets and their degree of spontaneous alignment. For aspect…

软凝聚态物质 · 物理学 2020-04-08 Arshia Atashpendar , Tim Ingenbrand , Tanja Schilling

In vascular targeted therapies, blood-borne carriers should realize sustained drug release from the luminal side towards the diseased tissue. In this context, such carriers are required to firmly adhere to the vessel walls for a sufficient…

流体动力学 · 物理学 2022-10-13 A. Coclite , G. Pascazio , M. D. de Tullio , P. Decuzzi

Sorting cells based on their intrinsic properties is a highly desirable objective, since changes in cell deformability are often associated with various stress conditions and diseases. Deterministic lateral displacement (DLD) devices offer…

流体动力学 · 物理学 2024-06-03 Zunmin Zhang , Wei Chien , Ewan Henry , Dmitry A. Fedosov , Gerhard Gompper

The erythrocyte (or red blood cell) sedimentation rate (ESR) is commonly interpreted as a measure of cell aggregation and as a biomarker of inflammation. It is well known that an increase of fibrinogen concentration, an aggregation-inducing…