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SARS-CoV-2 has disrupted the life of billions of people around the world since the first outbreak was officially declared in China at the beginning of 2020. Yet, important questions such as how deadly it is or its degree of spread within…

种群与进化 · 定量生物学 2021-03-01 Beatriz Seoane

A key challenge in estimating the infection fatality rate (IFR) -- and its relation with various factors of interest -- is determining the total number of cases. The total number of cases is not known because not everyone is tested, but…

Understanding how widely COVID-19 has spread is critical for examining the pandemic's progression. Despite efforts to carefully monitor the pandemic, the number of confirmed cases may underestimate the total number of infections. We…

种群与进化 · 定量生物学 2020-05-27 Christina Bohk-Ewald , Christian Dudel , Mikko Myrskylä

The determination of the infection fatality rate (IFR) for the novel SARS-CoV-2 coronavirus is a key aim for many of the field studies that are currently being undertaken in response to the pandemic. The IFR together with the basic…

The Infection Fatality Rate (IFR) of COVID-19 is difficult to estimate because the number of infections is unknown and there is a lag between each infection and the potentially subsequent death. We introduce a new approach for estimating…

计算机与社会 · 计算机科学 2021-09-29 Naveen Pai , Sean Zhang , Mor Harchol-Balter

The infection fatality rate (IFR) of the Coronavirus Disease 2019 (COVID-19) is one of the most discussed figures in the context of this pandemic. Using German COVID-19 surveillance data and age-group specific IFR estimates from multiple…

种群与进化 · 定量生物学 2021-01-22 Christian Staerk , Tobias Wistuba , Andreas Mayr

The infection fatality rate (IFR) of COVID-19 is one of the measures of disease impact that can be of importance for policy making. Here we show that many of the studies on which these estimates are based are scientifically flawed for…

种群与进化 · 定量生物学 2020-12-24 Chen Shen , Derrick Van Gennep , Alexander F. Siegenfeld , Yaneer Bar-Yam

An important parameter for COVID-19 is the case fatality rate (CFR). It has been applied to wide applications, including the measure of the severity of the infection, the estimation of the number of infected cases, risk assessment etc.…

应用统计 · 统计学 2026-02-10 Donghui Yan , Aiyou Chen , Buqing Yang

Different ways of calculating mortality ratios during epidemics have yielded very different results, particularly during the current COVID-19 pandemic. We formulate both a survival probability model and an associated infection…

种群与进化 · 定量生物学 2020-10-06 Lucas Böttcher , Mingtao Xia , Tom Chou

Knowing the infection fatality ratio (IFR) is of crucial importance for evidence-based epidemic management: for immediate planning; for balancing the life years saved against the life years lost due to the consequences of management; and…

定量方法 · 定量生物学 2020-08-11 Simon N. Wood , Ernst C. Wit , Matteo Fasiolo , Peter J. Green

Currently, novel coronavirus disease 2019 (COVID-19) is a big threat to global health. The rapid spread of the virus has created pandemic, and countries all over the world are struggling with a surge in COVID-19 infected cases. There are no…

应用统计 · 统计学 2020-09-08 Se Yoon Lee , Bowen Lei , Bani K. Mallick

The relative case fatality rates (CFRs) between groups and countries are key measures of relative risk that guide policy decisions regarding scarce medical resource allocation during the ongoing COVID-19 pandemic. In the middle of an active…

定量方法 · 定量生物学 2022-12-08 Anastasios Nikolas Angelopoulos , Reese Pathak , Rohit Varma , Michael I. Jordan

In the initial wave of the COVID-19 pandemic we observed great discrepancies in both infection and mortality rates between countries. Besides the biological and epidemiological factors, a multitude of social and economic criteria also…

物理与社会 · 物理学 2022-01-14 Viktor Stojkoski , Zoran Utkovski , Petar Jolakoski , Dragan Tevdovski , Ljupco Kocarev

The risk for severe illness and mortality from COVID-19 significantly increases with age. As a result, age-stratified modeling for COVID-19 dynamics is the key to study how to reduce hospitalizations and mortality from COVID-19. By taking…

种群与进化 · 定量生物学 2021-05-12 Xianhao Chen , Guangyu Zhu , Lan Zhang , Yuguang Fang , Linke Guo , Xinguang Chen

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

统计方法学 · 统计学 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian

The rapidly spreading Covid-19 that affected almost all countries, was first reported at the end of 2019. As a consequence of its highly infectious nature, countries all over the world have imposed extremely strict measures to control its…

种群与进化 · 定量生物学 2020-07-13 Semra Ahmetolan , Ayse Humeyra Bilge , Ali Demirci , Ayse Peker-Dobie , Onder Ergonul

The infections and fatalities due to SARS-CoV-2 virus for cases specific to India have been studied using a deterministic susceptible-exposed-infected-recovered-dead (SEIRD) compartmental model. One of the most significant epidemiological…

种群与进化 · 定量生物学 2020-06-09 Vishwajeet Jha

Most COVID-19 predictive modeling efforts use statistical or mathematical models to predict national- and state-level COVID-19 cases or deaths in the future. These approaches assume parameters such as reproduction time, test positivity…

We examine the age-structured SIR model, a variant of the classical Susceptible-Infected-Recovered (SIR) model of epidemic propagation, in the context of COVID-19. In doing so, we provide a theoretical basis for the model, perform an…

最优化与控制 · 数学 2022-03-11 Rohit Parasnis , Ryosuke Kato , Amol Sakhale , Massimo Franceschetti , Behrouz Touri

In this paper a Bayesian SEIR model is studied to estimate the proportion of the population infected with SARS-CoV-2, the virus responsible for COVID-19. To capture heterogeneity in the population and the effect of interventions to reduce…

种群与进化 · 定量生物学 2020-05-28 Henrik Hult , Martina Favero
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