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Chain molecules play important roles in industry and in living cells. Our focus here is on distinct ways of modeling the stiffness inherent in a chain molecule. We consider three types of stiffnesses -- one yielding an energy penalty for…

软凝聚态物质 · 物理学 2019-11-12 Tatjana Skrbic , Jayanth R. Banavar , Achille Giacometti

Semiflexible polymers in poor solvents exhibit a rich variety of collapsed morphologies, including globules, toroids, and rodlike bundles, arising from the competition between attractive interactions and chain stiffness. Computer…

统计力学 · 物理学 2026-01-22 Biman Bagchi

The competition between toroidal and rod-like conformations as possible ground states for DNA condensation is studied as a function of the stiffness, the length of the DNA and the form of the long-range interactions between neighboring…

Using a combination of the replica-exchange Monte Carlo algorithm and the multicanonical method, we investigate the influence of bending stiffness on the conformational phases of a bead-stick homopolymer model and present the pseudo-phase…

软凝聚态物质 · 物理学 2016-03-30 Martin Marenz , Wolfhard Janke

Semiflexible polymers are widely used as a paradigm for understanding structural phases in biomolecules including folding of proteins. Here, we compare bead-spring and bead-stick variants of coarse-grained semiflexible polymer models that…

软凝聚态物质 · 物理学 2024-02-16 Wolfhard Janke , Suman Majumder , Martin Marenz , Subhajit Paul

DNA toroids are compact torus-shaped bundles formed by one or multiple DNA molecules being condensed from the solution due to various condensing agents. It has been shown that the DNA toroidal bundles are twisted. However, the global…

软凝聚态物质 · 物理学 2025-04-01 Nhung T. T. Nguyen , Anh T. Ngo , Trinh X. Hoang

By means of extensive replica-exchange simulations of generic coarse-grained models for helical polymers, we systematically investigate the structural transitions into all possible helical phases for flexible and semiflexible elastic…

生物物理 · 物理学 2015-09-23 Matthew J. Williams , Michael Bachmann

A simple model of a circularly closed dsDNA in a poor solvent is considered as an example of a semi-flexible polymer with self-attraction. To find the ground states, the conformational energy is computed as a sum of the bending and…

生物物理 · 物理学 2013-04-25 E. L. Starostin

We introduce a novel coarse-grained bead-spring model for flexible polymers to systematically examine the effects of an adjusted bonded potential on the formation and stability of structural macrostates in a thermal environment. The density…

The mechanics of complex soft matter often cannot be understood in the classical physical frame of flexible polymers or rigid rods. The underlying constituents are semiflexible polymers, whose finite bending stiffness ($\kappa$) leads to…

Phase diagram of the ground states of DNA in a bad solvent is studied for a semi-flexible polymer model with a generalized local elastic bending potential characterized by a nonlinearity parameter $x$ and effective self-attraction promoting…

生物大分子 · 定量生物学 2016-01-28 Trinh X. Hoang , Hoa Lan Trinh , Achille Giacometti , Rudolf Podgornik , Jayanth R. Banavar , Amos Maritan

Confinement is a versatile and well-established tool to study the properties of polymers either to understand biological processes or to develop new nano-biomaterials. We investigate the conformations of a semiflexible polymer ring in weak…

软凝聚态物质 · 物理学 2010-06-25 Katja Ostermeir , Karen Alim , Erwin Frey

The dynamical response of a tethered semiflexible polymer with self-attractive interactions and subjected to an external force field is numerically investigated by varying stiffness and self-interaction strength. The chain is confined in…

软凝聚态物质 · 物理学 2022-11-09 A. Lamura

Solutions of semiflexible polymers confined by repulsive planar walls are studied by density functional theory and Molecular Dynamics simulations, to clarify the competition between the chain alignment favored by the wall and the depletion…

软凝聚态物质 · 物理学 2016-05-25 Sergei A. Egorov , Andrey Milchev , Peter Virnau , Kurt Binder

In this work we investigate structural properties of native states of a simple model for short flexible homopolymers, where the steric influence of monomeric side chains is effectively introduced by a thickness constraint. This geometric…

软凝聚态物质 · 物理学 2010-02-11 Thomas Vogel , Thomas Neuhaus , Michael Bachmann , Wolfhard Janke

The non-equilibrium structural and dynamical properties of semiflexible polymers confined to two dimensions are investigated by molecular dynamics simulations. Three different scenarios are considered: The force-extension relation of…

软凝聚态物质 · 物理学 2013-01-08 A. Lamura , R. G. Winkler

A single semiflexible polymer chain folds into a toroidal object under poor solvent conditions. In this study, we examined the morphological change in such a toroidal state as a function of the width and stiffness of the chain together with…

生物物理 · 物理学 2016-09-08 Y. Takenaka , Y. Yoshikawa , Y. Koyama , T. Kanbe , K. Yoshikawa

Semiflexible polymer models are widely used as a paradigm to understand structural phases in biomolecules including folding of proteins. Since stable knots are not so common in real proteins, the existence of stable knots in semiflexible…

软凝聚态物质 · 物理学 2021-07-14 Suman Majumder , Martin Marenz , Subhajit Paul , Wolfhard Janke

We use Wang-Landau and replica exchange techniques to study the effect of an increasing stiffness on the formation of secondary structures in protein-like systems. Two possible models are considered. In both models, a polymer chain is…

软凝聚态物质 · 物理学 2016-09-21 Tatjana Skrbic , Trinh X. Hoang , Achille Giacometti

We demonstrate that a semiflexible bundle of wormlike chains exhibits a state-dependent bending stiffness that alters fundamentally its scaling behavior with respect to the standard wormlike chain. We explore the equilibrium conformational…

统计力学 · 物理学 2007-07-26 Claus Heussinger , Mark Bathe , Erwin Frey
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