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Light-field microscopy (LFM) enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms. The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,…

光学 · 物理学 2025-02-24 Bohan Qu , Zhouyu Jin , You Zhou , Bo Xiong , Xun Cao

Fluorescence microscopy has enabled a dramatic development in modern biology by visualizing biological organisms with micrometer scale resolution. However, due to the diffraction limit, sub-micron/nanometer features are difficult to…

图像与视频处理 · 电气工程与系统科学 2021-03-10 Varun Mannam , Yide Zhang , Xiaotong Yuan , Scott Howard

Simulating the dynamics of electrons and other fermionic particles in quantum chemistry, materials science, and high-energy physics is one of the most promising applications of fault-tolerant quantum computers. However, the overhead in…

Invisible watermarking is essential for safeguarding digital content, enabling copyright protection and content authentication. However, existing watermarking methods fall short in robustness against regeneration attacks. In this paper, we…

密码学与安全 · 计算机科学 2024-10-29 Yiyang Guo , Ruizhe Li , Mude Hui , Hanzhong Guo , Chen Zhang , Chuangjian Cai , Le Wan , Shangfei Wang

Ultrasound-switchable fluorescence (USF) imaging was recently developed to overcome the limitation of the poor spatial resolution of the conventional fluorescence imaging in centimeter-deep tissue. However, in vivo USF imaging has not been…

生物物理 · 物理学 2018-10-12 Tingfeng Yao , Shuai Yu , Yang Liu , Baohong Yuan

To overcome the physical barriers caused by light diffraction, super-resolution techniques are often applied in fluorescence microscopy. State-of-the-art approaches require specific and often demanding acquisition conditions to achieve…

We introduce the Fast Free Memory method (FFM), a new fast method for the numerical evaluation of convolution products. Inheriting from the Fast Multipole Method, the FFM is a descent-only and kernel-independent algorithm. We give the…

数值分析 · 数学 2019-09-13 Matthieu Aussal , Marc Bakry

Multi-frequency Electrical Impedance Tomography (mfEIT) is an emerging biomedical imaging modality to reveal frequency-dependent conductivity distributions in biomedical applications. Conventional model-based image reconstruction methods…

图像与视频处理 · 电气工程与系统科学 2021-05-27 Zhou Chen , Jinxi Xiang , Pierre Bagnaninchi , Yunjie Yang

A prospective study was performed on neurosurgical samples from 18 patients to evaluate the use of Full-Field Optical Coherence Tomography (FF-OCT) in brain tumor diagnosis. FF-OCT captures en face slices of tissue samples at 1\mum…

Designing fluorescent small molecules with tailored optical and physicochemical properties requires navigating vast, underexplored chemical space while satisfying multiple objectives and constraints. Conventional generate-score-screen…

机器学习 · 计算机科学 2026-01-21 Yanheng Li , Zhichen Pu , Lijiang Yang , Zehao Zhou , Yi Qin Gao

We develop and experimentally demonstrate a methodology for a full molecular frame quantum tomography (MFQT) of dynamical polyatomic systems. We exemplify this approach through the complete characterization of an electronically…

Purpose: To describe a new methodology for tear-film dynamics assessment by observing fluorescein decay rate over time and to understand the relationship between the newly defined tear fluorescein washout rate (TFWR)and other measures of…

医学物理 · 物理学 2019-02-15 Izabela K. Garaszczuk , D. Robert Iskander

Protein rotational kinetics are essential for understanding macromolecular behavior in crowded environments, yet measuring these dynamics at solid-liquid interfaces remains a significant challenge due to low signal strengths. Here, we…

A new method for the reconstruction of the projected mass distribution of clusters of galaxies from the image distortion of background galaxies is discussed. This method is essentially equivalent to the one we developed previously, i.e.,…

天体物理学 · 物理学 2007-05-23 Stella Seitz , Peter Schneider

Quantum fluctuation is introduced into the Markov random fields (MRF's) model for image restoration in the context of Bayesian approach. We investigate the dependence of the quantum fluctuation on the quality of BW image restoration by…

无序系统与神经网络 · 物理学 2009-10-31 Jun-ichi Inoue

Computed tomography (CT) is a widely used medical imaging technique to scan internal structures of a body, typically involving collimation and mechanical rotation. Compton scatter tomography (CST) presents an interesting alternative to…

图像与视频处理 · 电气工程与系统科学 2024-06-06 Ishak Ayad , Cécilia Tarpau , Javier Cebeiro , Maï K. Nguyen

We present a quantum algorithmic framework for simulating phase-contrast transmission electron microscopy (CTEM) image formation using a fault-tolerant, gate-based quantum circuit model. The electron wavefield on an $N\times N$ grid is…

量子物理 · 物理学 2026-02-17 Sean D. Lam , Roberto dos Reis

Machine learning techniques have opened new avenues for real-time quantum state tomography (QST). In this work, we demonstrate the deployment of machine learning-based QST onto edge devices, specifically utilizing field programmable gate…

Objective: Survival rate of oral squamous cell carcinoma (OSCC) patients is very poor and can be improved using highly sensitive, specific and accurate techniques. Autofluorescence and fluorescence techniques are very sensitive and useful…

The knowledge of the exact structure of the optical system PSF enables a high-quality image reconstruction in fluorescence microscopy. Accurate PSF models account for the vector nature of light and the phase and amplitude modifications.…