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A phylogenetic tree is a way to organize a finite set of species, individuals or other sources of related data. The species for which we have existing DNA data make up the set of leaves of the tree. The balanced minimal evolution method of…

组合数学 · 数学 2016-08-05 Stefan Forcey , Logan Keefe , William Sands

Distance-based phylogenetic algorithms attempt to solve the NP-hard least squares phylogeny problem by mapping an arbitrary dissimilarity map representing biological data to a tree metric. The set of all dissimilarity maps is a Euclidean…

种群与进化 · 定量生物学 2013-07-24 Ruth Davidson , Seth Sullivant

The perfect phylogeny mixture (PPM) model is useful due to its simplicity and applicability in scenarios where mutations can be assumed to accumulate monotonically over time. It is the underlying model in many tools that have been used, for…

种群与进化 · 定量生物学 2026-01-01 John Marangola , Azadeh Sheikholeslami , José Bento

Phylogenetic networks extend phylogenetic trees to model non-vertical inheritance, by which a lineage inherits material from multiple parents. The computational complexity of estimating phylogenetic networks from genome-wide data with…

种群与进化 · 定量生物学 2022-06-28 Jingcheng Xu , Cécile Ané

Network (or matrix) reconstruction is a general problem which occurs if the margins of a matrix are given and the matrix entries need to be predicted. In this paper we show that the predictions obtained from the iterative proportional…

统计方法学 · 统计学 2019-09-05 Michael Lebacher , Göran Kauermann

The supertree construction problem is about combining several phylogenetic trees with possibly conflicting information into a single tree that has all the leaves of the source trees as its leaves and the relationships between the leaves are…

计算工程、金融与科学 · 计算机科学 2020-02-19 Laura Koponen , Emilia Oikarinen , Tomi Janhunen , Laura Säilä

A tanglegram consists of two rooted binary trees with the same number of leaves and a perfect matching between the leaves of the trees. Given a size-$n$ tanglegram, i.e., a tanglegram for two trees with $n$ leaves, a multiset of induced…

组合数学 · 数学 2025-08-18 Ann Clifton , Eva Czabarka , Kevin Liu , Sarah Loeb , Utku Okur , Laszlo Szekely , Kristina Wicke

A communication network can be modeled as a directed connected graph with edge weights that characterize performance metrics such as loss and delay. Network tomography aims to infer these edge weights from their pathwise versions measured…

最优化与控制 · 数学 2019-08-12 Mahmood Ettehad , Nick Duffield , Gregory Berkolaiko

We consider the phylogenetic tree reconstruction problem with insertions and deletions (indels). Phylogenetic algorithms proceed under a model where sequences evolve down the model tree, and given sequences at the leaves, the problem is to…

数据结构与算法 · 计算机科学 2019-02-22 Arun Ganesh , Qiuyi Zhang

Driven by the need for better models that allow one to shed light into the question how life's diversity has evolved, phylogenetic networks have now joined phylogenetic trees in the center of phylogenetics research. Like phylogenetic trees,…

组合数学 · 数学 2016-10-04 Philippe Gambette , Katharina T. Huber

Complex systems are usually represented as an intricate set of relations between their components forming a complex graph or network. The understanding of their functioning and emergent properties are strongly related to their structural…

数据分析、统计与概率 · 物理学 2014-01-08 Sergio Gomez , Alberto Fernandez , Clara Granell , Alex Arenas

Bayesian Markov chain Monte Carlo explores tree space slowly, in part because it frequently returns to the same tree topology. An alternative strategy would be to explore tree space systematically, and never return to the same topology. In…

种群与进化 · 定量生物学 2018-11-28 Chris Whidden , Brian C. Claywell , Thayer Fisher , Andrew F. Magee , Mathieu Fourment , Frederick A. Matsen

Kloks, Kratsch, and Spinrad showed how treewidth and minimum-fill, NP-hard combinatorial optimization problems related to minimal triangulations, are broken into subproblems by block subgraphs defined by minimal separators. These ideas were…

离散数学 · 计算机科学 2013-03-19 Rob Gysel

Recent work has proven the existence of extreme inbreeding in a European ancestry sample taken from the contemporary UK population \cite{nature_01}. This result brings our attention again to a math problem related to inbreeding family trees…

种群与进化 · 定量生物学 2021-09-08 C. Jarne , F A. Gómez Albarracín , M. Caruso

A phylogenetic tree is a graphical representation of an evolutionary history of taxa in which the leaves correspond to the taxa and the non-leaves correspond to speciations. One of important problems in phylogenetic analysis is to assemble…

组合数学 · 数学 2022-02-25 Hiroshi Hirai , Yuni Iwamasa

We present the first fixed-parameter algorithm for constructing a tree-child phylogenetic network that displays an arbitrary number of binary input trees and has the minimum number of reticulations among all such networks. The algorithm…

离散数学 · 计算机科学 2019-07-22 Leo van Iersel , Remie Janssen , Mark Jones , Yukihiro Murakami , Norbert Zeh

Recently, so-called treebased phylogenetic networks have gained considerable interest in the literature, where a treebased network is a network that can be constructed from a phylogenetic tree, called the base tree, by adding additional…

种群与进化 · 定量生物学 2019-11-28 Mareike Fischer , Michelle Galla , Lina Herbst , Yangjing Long , Kristina Wicke

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

种群与进化 · 定量生物学 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

In this work, we present a neural approach to reconstructing rooted tree graphs describing hierarchical interactions, using a novel representation we term the Lowest Common Ancestor Generations (LCAG) matrix. This compact formulation is…

Given a dense triplet set $\mathcal{T}$, there arise two interesting questions: Does there exists any phylogenetic network consistent with $\mathcal{T}$? And if so, can we find an effective algorithm to construct one? For cases of networks…

种群与进化 · 定量生物学 2009-01-13 Thu-Hien To , Michel Habib