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Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…

The application of Artificial Intelligence (AI) in healthcare has been revolutionary, especially with the recent advancements in transformer-based Large Language Models (LLMs). However, the task of understanding unstructured electronic…

计算与语言 · 计算机科学 2023-08-08 Shivani Shekhar , Simran Tiwari , T. C. Rensink , Ramy Eskander , Wael Salloum

This paper introduces a novel low-cost device prototype for the automatic diagnosis of diseases, utilizing inputted symptoms and personal background. The engineering goal is to solve the problem of limited healthcare access with a single…

计算机与社会 · 计算机科学 2019-01-07 Neil Deshmukh

Missing data is a ubiquitous problem. It is especially challenging in medical settings because many streams of measurements are collected at different - and often irregular - times. Accurate estimation of those missing measurements is…

机器学习 · 计算机科学 2017-11-27 Jinsung Yoon , William R. Zame , Mihaela van der Schaar

With the development of deep learning (DL) techniques, rotating machinery intelligent diagnosis has gone through tremendous progress with verified success and the classification accuracies of many DL-based intelligent diagnosis algorithms…

信号处理 · 电气工程与系统科学 2020-08-20 Zhibin Zhao , Tianfu Li , Jingyao Wu , Chuang Sun , Shibin Wang , Ruqiang Yan , Xuefeng Chen

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

人工智能 · 计算机科学 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Multimodal large models have shown great potential in automating pathology image analysis. However, current multimodal models for gastrointestinal pathology are constrained by both data quality and reasoning transparency: pervasive noise…

图像与视频处理 · 电气工程与系统科学 2025-07-25 Minxi Ouyang , Lianghui Zhu , Yaqing Bao , Qiang Huang , Jingli Ouyang , Tian Guan , Xitong Ling , Jiawen Li , Song Duan , Wenbin Dai , Li Zheng , Xuemei Zhang , Yonghong He

The ability of deep learning (DL) to improve the practice of medicine and its clinical outcomes faces a looming obstacle: model interpretation. Without description of how outputs are generated, a collaborating physician can neither resolve…

机器学习 · 计算机科学 2020-06-30 Christopher Snyder , Sriram Vishwanath

Explainable disease diagnosis, which leverages patient information (e.g., signs and symptoms) and computational models to generate probable diagnoses and reasonings, offers clear clinical values. However, when clinical notes encompass…

Despite rare diseases affecting 1 in 10 Americans, their differential diagnosis remains challenging. Due to their impressive recall abilities, large language models (LLMs) have been recently explored for differential diagnosis. Existing…

Reliable Alzheimer's disease (AD) diagnosis increasingly relies on multimodal assessments combining structural Magnetic Resonance Imaging (MRI) and Electronic Health Records (EHR). However, deploying these models is bottlenecked by modality…

计算机视觉与模式识别 · 计算机科学 2026-03-04 Guanchen Wu , Zhe Huang , Yuzhang Xie , Runze Yan , Akul Chopra , Deqiang Qiu , Xiao Hu , Fei Wang , Carl Yang

Structured data offers a sophisticated mechanism for the organization of information. Existing methodologies for the text-serialization of structured data in the context of large language models fail to adequately address the heterogeneity…

计算与语言 · 计算机科学 2024-02-20 YiQiu Guo , Yuchen Yang , Ya Zhang , Yu Wang , Yanfeng Wang

The goal of precision medicine is to provide individualized treatment at each stage of chronic diseases, a concept formalized by Dynamic Treatment Regimes (DTR). These regimes adapt treatment strategies based on decision rules learned from…

统计方法学 · 统计学 2025-06-09 Sophia Yazzourh , Nicolas Savy , Philippe Saint-Pierre , Michael R. Kosorok

While large language models (LLMs) have achieved state-of-the-art performance on a wide range of medical question answering (QA) tasks, they still face challenges with hallucinations and outdated knowledge. Retrieval-augmented generation…

计算与语言 · 计算机科学 2024-02-26 Guangzhi Xiong , Qiao Jin , Zhiyong Lu , Aidong Zhang

Deep neural networks (DNN) have achieved unprecedented performance in computer-vision tasks almost ubiquitously in business, technology, and science. While substantial efforts are made to engineer highly accurate architectures and provide…

图像与视频处理 · 电气工程与系统科学 2022-09-08 Sumedha Singla

Electrocardiograms (ECG), which record the electrophysiological activity of the heart, have become a crucial tool for diagnosing these diseases. In recent years, the application of deep learning techniques has significantly improved the…

信号处理 · 电气工程与系统科学 2024-06-26 Wei Huang , Ning Wang , Panpan Feng , Haiyan Wang , Zongmin Wang , Bing Zhou

Electronic Health Records (EHR) data analysis plays a crucial role in healthcare system quality. Because of its highly complex underlying causality and limited observable nature, causal inference on EHR is quite challenging. Deep Learning…

机器学习 · 计算机科学 2022-10-28 Jia Li , Haoyu Yang , Xiaowei Jia , Vipin Kumar , Michael Steinbach , Gyorgy Simon

Electronic Health Records (EHRs) are pivotal in clinical practices, yet their retrieval remains a challenge mainly due to semantic gap issues. Recent advancements in dense retrieval offer promising solutions but existing models, both…

信息检索 · 计算机科学 2025-07-25 Zhengyun Zhao , Huaiyuan Ying , Yue Zhong , Sheng Yu

Recent advances in reasoning with large language models (LLMs)has shown remarkable reasoning capabilities in domains such as mathematics and coding, yet their application to clinical diagnosis remains underexplored. Here, we introduce…

计算与语言 · 计算机科学 2025-04-16 Wuyang Lan , Wenzheng Wang , Changwei Ji , Guoxing Yang , Yongbo Zhang , Xiaohong Liu , Song Wu , Guangyu Wang

Image registration is a critical component in the applications of various medical image analyses. In recent years, there has been a tremendous surge in the development of deep learning (DL)-based medical image registration models. This…

图像与视频处理 · 电气工程与系统科学 2022-04-26 Subrato Bharati , M. Rubaiyat Hossain Mondal , Prajoy Podder , V. B. Surya Prasath