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In recent years, spatial and spatio-temporal modeling have become an important area of research in many fields (epidemiology, environmental studies, disease mapping). In this work we propose different spatial models to study hospital…

应用统计 · 统计学 2010-06-21 Erik A. Sauleau , Valentina Mameli , Monica Musio

This tutorial shows how various Bayesian survival models can be fitted using the integrated nested Laplace approximation in a clear, legible, and comprehensible manner using the INLA and INLAjoint R-packages. Such models include accelerated…

统计方法学 · 统计学 2024-03-19 Danilo Alvares , Janet van Niekerk , Elias Teixeira Krainski , Håvard Rue , Denis Rustand

This article focuses on measurement error in covariates in regression analyses in which the aim is to estimate the association between one or more covariates and an outcome, adjusting for confounding. Error in covariate measurements, if…

统计方法学 · 统计学 2019-10-16 Ruth H. Keogh , Jonathan W. Bartlett

Joint models for longitudinal and time-to-event data are increasingly used in health research to characterize the association between biomarker trajectories and the risk of clinical events. However, these models usually assume a linear…

统计方法学 · 统计学 2026-04-21 Denis Rustand , Håvard Rue , Lisa Le Gall , Karen Leffondre

Generalized linear mixed models (GLMM) encompass large class of statistical models, with a vast range of applications areas. GLMM extends the linear mixed models allowing for different types of response variable. Three most common data…

应用统计 · 统计学 2017-04-25 Wagner Hugo Bonat , Paulo Justiniano Ribeiro , Silvia emiko Shimakura

Most practical data science problems encounter missing data. A wide variety of solutions exist, each with strengths and weaknesses that depend upon the missingness-generating process. Here we develop a theoretical framework for training and…

机器学习 · 计算机科学 2022-11-15 Jahan C. Penny-Dimri , Christoph Bergmeir , Julian Smith

Integrated Nested Laplace Approximation provides a fast and effective method for marginal inference on Bayesian hierarchical models. This methodology has been implemented in the R-INLA package which permits INLA to be used from within R…

统计计算 · 统计学 2021-06-01 Virgilio Gomez-Rubio , Roger S. Bivand , Håvard Rue

The key operation in Bayesian inference, is to compute high-dimensional integrals. An old approximate technique is the Laplace method or approximation, which dates back to Pierre- Simon Laplace (1774). This simple idea approximates the…

We introduce a new copula-based correction for generalized linear mixed models (GLMMs) within the integrated nested Laplace approximation (INLA) approach for approximate Bayesian inference for latent Gaussian models. While INLA is usually…

统计计算 · 统计学 2015-12-16 Egil Ferkingstad , Håvard Rue

Marginal structural models (MSMs) are commonly used to estimate causal intervention effects in longitudinal non-randomised studies. A common issue when analysing data from observational studies is the presence of incomplete confounder data,…

统计方法学 · 统计学 2019-12-02 Clemence Leyrat , James R Carpenter , Sebastien Bailly , Elizabeth J Willamson

Integrating heterogeneous data sources and expert knowledge is essential for overcoming data scarcity and enhancing estimation accuracy. Two main frameworks naturally arise to perform the integration of these multiple sources: sequential…

统计方法学 · 统计学 2025-11-26 Mario Figueira , David Conesa , Antonio López-Quílez , Håvard Rue

We propose a spatio-temporal data-fusion framework for point data and gridded data with variables observed on different spatial supports. A latent Gaussian field with a Mat\'ern-SPDE prior provides a continuous space representation, while…

统计方法学 · 统计学 2025-11-19 Weiyue Zheng , Andrew Elliott , Claire Miller , Marian Scott

Ecological Momentary Assessments (EMA) capture real-time thoughts and behaviors in natural settings, producing rich longitudinal data for statistical and physiological analyses. However, the robustness of these analyses can be compromised…

统计方法学 · 统计学 2023-11-21 Yiheng Wei , Donald Hedeker

Bayesian structural equation modelling (BSEM) offers many advantages such as principled uncertainty quantification, small-sample regularisation, and flexible model specification. However, the Markov chain Monte Carlo (MCMC) methods on which…

统计计算 · 统计学 2026-05-20 Haziq Jamil , Håvard Rue

The Laplace approximation (LA) has been proposed as a method for approximating the marginal likelihood of statistical models with latent variables. However, the approximate maximum likelihood estimators (MLEs) based on the LA are often…

统计方法学 · 统计学 2022-07-21 Jeongseop Han , Youngjo Lee

Bayesian hierarchical models are increasingly popular for realistic modelling and analysis of complex data. This trend is accompanied by the need for flexible, general, and computationally efficient methods for model criticism and conflict…

统计方法学 · 统计学 2017-11-02 Egil Ferkingstad , Leonhard Held , Håvard Rue

Bayesian hierarchical models with latent Gaussian layers have proven very flexible in capturing complex stochastic behavior and hierarchical structures in high-dimensional spatial and spatio-temporal data. Whereas simulation-based Bayesian…

统计方法学 · 统计学 2017-08-10 Thomas Opitz

Missing data is a fundamental challenge in data science, significantly hindering analysis and decision-making across a wide range of disciplines, including healthcare, bioinformatics, social science, e-commerce, and industrial monitoring.…

机器学习 · 统计学 2026-05-12 Jicong Fan

The Integrated Nested Laplace Approximation (INLA) is a convenient way to obtain approximations to the posterior marginals for parameters in Bayesian hierarchical models when the latent effects can be expressed as a Gaussian Markov Random…

统计计算 · 统计学 2017-02-14 Virgilio Gómez-Rubio , Francisco Palmí-Perales

It is argued that the Calibrated Bayesian (CB) approach to statistical inference capitalizes on the strength of Bayesian and frequentist approaches to statistical inference. In the CB approach, inferences under a particular model are…

统计方法学 · 统计学 2011-08-10 Roderick Little