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We investigate methods for penalized regression in the presence of missing observations. This paper introduces a method for estimating the parameters which compensates for the missing observations. We first, derive an unbiased estimator of…

应用统计 · 统计学 2013-10-09 Yunjin Choi , Robert Tibshirani

In a bivariate meta-analysis the number of diagnostic studies involved is often very low so that frequentist methods may result in problems. Bayesian inference is attractive as informative priors that add small amount of information can…

统计方法学 · 统计学 2015-12-22 Jingyi Guo , Håvard Rue , Andrea Riebler

Missing data is an universal problem in statistics. We develop a unified framework for estimating parameters defined by general estimating equations under a missing-at-random (MAR) mechanism, based on generalized entropy calibration…

统计方法学 · 统计学 2026-03-31 Mst Moushumi Pervin , Hengfang Wang , Jae Kwang Kim

Various computational challenges arise when applying Bayesian inference approaches to complex hierarchical models. Sampling-based inference methods, such as Markov Chain Monte Carlo strategies, are renowned for providing accurate results…

统计方法学 · 统计学 2022-03-29 Cristian Chiuchiolo , Janet van Niekerk , Håvard Rue

We propose an l1-regularized likelihood method for estimating the inverse covariance matrix in the high-dimensional multivariate normal model in presence of missing data. Our method is based on the assumption that the data are missing at…

统计方法学 · 统计学 2012-02-28 Nicolas Städler , Peter Bühlmann

In pharmacoepidemiology, safety and effectiveness are frequently evaluated using readily available administrative and electronic health records data. In these settings, detailed confounder data are often not available in all data sources…

This research deals with the estimation and imputation of missing data in longitudinal models with a Poisson response variable inflated with zeros. A methodology is proposed that is based on the use of maximum likelihood, assuming that data…

统计方法学 · 统计学 2024-09-18 D. S. Martinez-Lobo , O. O. Melo , N. A. Cruz

The integrated nested Laplace approximation (INLA) method has become a popular approach for computationally efficient approximate Bayesian computation. In particular, by leveraging sparsity in random effect precision matrices, INLA is…

统计方法学 · 统计学 2024-07-02 Finn Lindgren , Fabian Bachl , Janine Illian , Man Ho Suen , Håvard Rue , Andrew E. Seaton

This work addresses the problem of missing data in time-series analysis focusing on (a) estimation of model parameters in the presence of missing data and (b) reconstruction of missing data. Standard approaches used to solve these problems…

统计方法学 · 统计学 2020-01-01 Dimitri Igdalov , Olga Kaiser , Ilia Horenko

The problem of monotone missing data has been broadly studied during the last two decades and has many applications in different fields such as bioinformatics or statistics. Commonly used imputation techniques require multiple iterations…

机器学习 · 计算机科学 2020-09-25 Thu Nguyen , Duy H. M. Nguyen , Huy Nguyen , Binh T. Nguyen , Bruce A. Wade

Missing data theory deals with the statistical methods in the occurrence of missing data. Missing data occurs when some values are not stored or observed for variables of interest. However, most of the statistical theory assumes that data…

统计方法学 · 统计学 2021-10-26 Luis Alejandro Masmela-Caita , Thais Paiva Galletti , Marcos Oliveira Prates

We propose the approximate Laplace approximation (ALA) to evaluate integrated likelihoods, a bottleneck in Bayesian model selection. The Laplace approximation (LA) is a popular tool that speeds up such computation and equips strong model…

统计计算 · 统计学 2021-10-07 David Rossell , Oriol Abril , Anirban Bhattacharya

Missing data is a common problem in clinical data collection, which causes difficulty in the statistical analysis of such data. To overcome problems caused by incomplete data, we propose a new imputation method called projective resampling…

统计方法学 · 统计学 2021-06-17 Zishu Zhan , Xiangjie Li , Jingxiao Zhang

Differential analysis is a routine procedure in the statistical analysis toolbox across many applied fields, including quantitative proteomics, the main illustration of the present paper. The state-of-the-art limma approach uses a…

统计方法学 · 统计学 2025-12-12 Marie Chion , Arthur Leroy

Real-world clinical time series data sets exhibit a high prevalence of missing values. Hence, there is an increasing interest in missing data imputation. Traditional statistical approaches impose constraints on the data-generating process…

机器学习 · 计算机科学 2020-01-13 Yang Guo , Zhengyuan Liu , Pavitra Krishnswamy , Savitha Ramasamy

This paper introduces the R package INLAjoint, designed as a toolbox for fitting a diverse range of regression models addressing both longitudinal and survival outcomes. INLAjoint relies on the computational efficiency of the integrated…

统计方法学 · 统计学 2024-04-04 Denis Rustand , Janet van Niekerk , Elias Teixeira Krainski , Håvard Rue

Cure models in survival analysis deal with populations in which a part of the individuals cannot experience the event of interest. Mixture cure models consider the target population as a mixture of susceptible and non-susceptible…

统计计算 · 统计学 2018-06-26 Elena Lázaro , Carmen Armero , Virgilio Gómez-Rubio

Quantile regression provides a consistent approach to investigating the association between covariates and various aspects of the distribution of the response beyond the mean. When the regression covariates are measured with errors,…

统计方法学 · 统计学 2023-02-09 Roger S. Zoh , Annie Yu , Carmen Tekwe

Modern datasets commonly feature both substantial missingness and many variables of mixed data types, which present significant challenges for estimation and inference. Complete case analysis, which proceeds using only the observations with…

统计方法学 · 统计学 2023-04-10 Joseph Feldman , Daniel R. Kowal

Markov chain Monte Carlo (MCMC) methods remain the mainstay of Bayesian estimation of structural equation models (SEM), though they often incur a high computational cost. We present a bespoke approximate Bayesian approach to SEM, drawing on…

统计方法学 · 统计学 2026-05-20 Haziq Jamil , Håvard Rue