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相关论文: Causal Mediation Analysis with a Three-Dimensional…

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Mediation analysis is a powerful tool for studying causal pathways between exposure, mediator, and outcome variables of interest. While classical mediation analysis using observational data often requires strong and sometimes unrealistic…

统计方法学 · 统计学 2024-05-20 Rita Qiuran Lyu , Chong Wu , Xinwei Ma , Jingshen Wang

We consider the problem of identifying intermediate variables (or mediators) that regulate the effect of a treatment on a response variable. While there has been significant research on this classical topic, little work has been done when…

统计方法学 · 统计学 2021-07-29 Abhishek Chakrabortty , Preetam Nandy , Hongzhe Li

Summary statistics of genome-wide association studies (GWAS) teach causal relationship between millions of genetic markers and tens and thousands of phenotypes. However, underlying biological mechanisms are yet to be elucidated. We can…

机器学习 · 统计学 2019-01-25 Yongjin Park , Abhishek Sarkar , Khoi Nguyen , Manolis Kellis

Deep learning has revolutionized the field of artificial intelligence. Based on the statistical correlations uncovered by deep learning-based methods, computer vision has contributed to tremendous growth in areas like autonomous driving and…

计算机视觉与模式识别 · 计算机科学 2023-08-01 Kexuan Zhang , Qiyu Sun , Chaoqiang Zhao , Yang Tang

Mediation analysis is widely used for exploring treatment mechanisms; however, it faces challenges when nonignorable missing confounders are present. Efficient inference of mediation effects and the efficiency loss due to nonignorable…

统计方法学 · 统计学 2026-04-22 Jiawei Shan , Wei Li , Chunrong Ai

Visual representation learning is ubiquitous in various real-world applications, including visual comprehension, video understanding, multi-modal analysis, human-computer interaction, and urban computing. Due to the emergence of huge…

计算机视觉与模式识别 · 计算机科学 2023-03-23 Yang Liu , Yushen Wei , Hong Yan , Guanbin Li , Liang Lin

Bayesian causal inference offers a principled approach to policy evaluation of proposed interventions on mediators or time-varying exposures. We outline a general approach to the estimation of causal quantities for settings with…

统计方法学 · 统计学 2019-02-28 Leah Comment , Brent A. Coull , Corwin Zigler , Linda Valeri

Causal inference has numerous real-world applications in many domains, such as health care, marketing, political science, and online advertising. Treatment effect estimation, a fundamental problem in causal inference, has been extensively…

机器学习 · 计算机科学 2023-02-03 Zhixuan Chu , Jianmin Huang , Ruopeng Li , Wei Chu , Sheng Li

Curating a large scale medical imaging dataset for machine learning applications is both time consuming and expensive. Balancing the workload between model development, data collection and annotations is difficult for machine learning…

人工智能 · 计算机科学 2022-06-07 Athanasios Vlontzos , Hadrien Reynaud , Bernhard Kainz

Mediation analyses allow researchers to quantify the effect of an exposure variable on an outcome variable through a mediator variable. If a binary mediator variable is misclassified, the resulting analysis can be severely biased.…

统计方法学 · 统计学 2024-07-19 Kimberly A. Hochstedler Webb , Martin T. Wells

On the promise that if human users know the cause of an output, it would enable them to grasp the process responsible for the output, and hence provide understanding, many explainable methods have been proposed to indicate the cause for the…

计算机视觉与模式识别 · 计算机科学 2023-09-06 Armando Villegas-Jimenez , Daniel Flores-Araiza , Francisco Lopez-Tiro , Gilberto Ochoa-Ruiz andand Christian Daul

Many epidemiological questions concern potential interventions to alter the pathways presumed to mediate an association. For example, we consider a study that investigates the benefit of interventions in young adulthood for ameliorating the…

统计方法学 · 统计学 2020-07-14 Margarita Moreno-Betancur , Paul Moran , Denise Becker , George C Patton , John B Carlin

In epidemiological research, causal models incorporating potential mediators along a pathway are crucial for understanding how exposures influence health outcomes. This work is motivated by integrated epidemiological and blood biomarker…

统计方法学 · 统计学 2024-11-28 Youngho Bae , Chanmin Kim , Fenglei Wang , Qi Sun , Kyu Ha Lee

Researchers are often interested in analyzing conditional treatment effects. One variant of this is "causal moderation," which implies that intervention upon a third (moderator) variable would alter the treatment effect. This study…

统计方法学 · 统计学 2020-08-25 Kirk Bansak

Decomposing an exposure effect on an outcome into separate natural indirect effects through multiple mediators requires strict assumptions, such as correctly postulating the causal structure of the mediators, and no unmeasured confounding…

统计方法学 · 统计学 2021-02-04 Wen Wei Loh , Beatrijs Moerkerke , Tom Loeys , Stijn Vansteelandt

During the past few years, mediation analysis has gained increasing popularity across various research fields. The primary objective of mediation analysis is to examine the direct impact of exposure on outcome, as well as the indirect…

统计计算 · 统计学 2023-05-18 Haixiang Zhang , Xin Li

We empirically demonstrate that graphical models can be a valuable tool in the identification of mediating variables in causal pathways. We make use of graphical models to elucidate the causal pathway through which the treatment influences…

应用统计 · 统计学 2019-07-11 Adrian Dobra , Katherine Buhikire , Joachim G. Voss

Mediation analysis draws increasing attention in many scientific areas such as genomics, epidemiology and finance. In this paper, we propose new statistical inference procedures for high dimensional mediation models, in which both the…

统计方法学 · 统计学 2021-08-30 Xu Guo , Runze Li , Jingyuan Liu , Mudong Zeng

The paper considers mediation analysis with longitudinal data under latent growth curve models within a counterfactual framework. Estimators and their standard errors are derived for natural direct and indirect effects when the mediator,…

统计方法学 · 统计学 2021-03-11 Adam J. Sullivan , Douglas D. Gunzler , Nathan Morris , Tyler J. VanderWeele

E-commerce companies have a number of online products, such as organic search, sponsored search, and recommendation modules, to fulfill customer needs. Although each of these products provides a unique opportunity for users to interact with…

应用统计 · 统计学 2020-06-23 Xuan Yin , Liangjie Hong