相关论文: Multiscale constitutive framework of 1D blood flow…
In a companion study \cite{patterson2020computing2D}, we present a numerical method for simulating 2D viscous flow through an open compliant closed channel, drive by pressure gradient. We consider the highly viscous regime, where fluid…
Flow networks can describe many natural and artificial systems. We present a model for a flow system that allows for volume accumulation, includes conduits with a non-linear relation between current and pressure difference, and can be…
In this paper, a novel deep learning framework is proposed for temporal super-resolution simulation of blood vessel flows, in which a high-temporal-resolution time-varying blood vessel flow simulation is generated from a…
We develop a lattice Boltzmann equation method for simulating multi-phase immiscible fluid flows with variation of density and viscosity, based on the model proposed by Gunstensen {\em et al} for two-component immiscible fluids. The…
In this work, we consider two kinds of model reduction techniques to simulate blood flow through the largest systemic arteries, where a stenosis is located in a peripheral artery i.e. in an artery that is located far away from the heart.…
We propose a seamless multiscale method which approximates the macroscopic behavior of the passive advection-diffusion equations with steady incompressible velocity fields with multi-spatial scales. The method uses decompositions of the…
The paper is devoted to homogenization of two-phase incompressible viscoelastic flows with disordered microstructure. We study two cases. In the first case, both phases are modeled as Kelvin-Voight viscoelastic materials. In the second…
Microvessels -blood vessels with diameter less than 200 microns- form large, intricate networks organized into arterioles, capillaries and venules. In these networks, the distribution of flow and pressure drop is a highly interlaced…
The majority of available numerical algorithms for interfacial two-phase flows either treat both fluid phases as incompressible (constant density) or treat both phases as compressible (variable density). This presents a limitation for the…
In this paper, we present a framework for multiscale topology optimization of fluid-flow devices. The objective is to minimize dissipated power, subject to a desired contact-area. The proposed strategy is to design optimal microstructures…
We present a generalizable uncertainty quantification (UQ) and visualization framework for lattice Boltzmann method simulations of high Reynolds number vascular flows, demonstrated on a patient-specific stenosed aorta. The framework…
The nonlinear inviscid 1D blood flow equations are studied analytically using the method of characteristics. The boundary value problem with a triangle-shaped boundary data at the aortic outlet is considered. The pressure-velocity profile,…
A second derivative-based moment method is proposed for describing the thickness and shape of the region where viscous forces are dominant in turbulent boundary layer flows. Rather than the fixed location sublayer model presently employed,…
Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…
Motivated by the complex rheological behaviors observed in small/micro scale blood vessels, such as the Fahraeus effect, plasma-skimming, shear-thinning, etc., we develop a non-linear suspension model for blood. The viscosity is assumed to…
Hemodynamics in the aorta from computational fluid dynamics (CFD) simulations can provide a comprehensive analysis of relevant cardiovascular diseases. Coupling the three-element Windkessel model with the patient-specific CFD simulation to…
Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed…
We investigate avascular tumour growth as a two-phase process consisting of cells and liquid. Based on the one-dimensional continuum moving-boundary model formulated by (Byrne, King, McElwain, Preziosi, Applied Mathematics Letters, 2003,…
In this article, we show how to construct a numerical method for solving hyperbolic problems, whether linear or nonlinear, using a continuous representation of the variables and their mean value in each triangular element. This type of…
Systematic in vivo validations of computational models of the aortic valve remain scarce, despite successful validation against in vitro data. Utilizing a combination of computed tomography and 4D flow magnetic resonance imaging data, we…