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Current understanding of the critical outbreak condition on temporal networks relies on approximations (time scale separation, discretization) that may bias the results. We propose a theoretical framework to compute the epidemic threshold…

物理与社会 · 物理学 2018-02-08 Eugenio Valdano , Michele Re Fiorentin , Chiara Poletto , Vittoria Colizza

Infectious diseases occur when pathogens from other individuals or animals infect a person, resulting in harm to both individuals and society as a whole. The outbreak of such diseases can pose a significant threat to human health. However,…

种群与进化 · 定量生物学 2024-10-24 Ghazaleh Babanejaddehaki , Aijun An , Manos Papagelis

Stochastic epidemic models describe the dynamics of an epidemic as a disease spreads through a population. Typically, only a fraction of cases are observed at a set of discrete times. The absence of complete information about the time…

统计计算 · 统计学 2017-02-14 Jonathan Fintzi , Xiang Cui , Jon Wakefield , Vladimir N. Minin

Human to human transmissible infectious diseases spread in a population using human interactions as its transmission vector. The early stages of such an outbreak can be modeled by a graph whose edges encode these interactions between…

种群与进化 · 定量生物学 2020-06-11 Goncalo Oliveira

Metapopulation models describing cities with different populations coupled by the travel of individuals are of great importance in the understanding of disease spread on a large scale. An important example is the Rvachev-Longini model [{\it…

种群与进化 · 定量生物学 2007-09-19 Aurelien Gautreau , Alain Barrat , Marc Barthelemy

Networks of contacts capable of spreading infectious diseases are often observed to be highly heterogeneous, with the majority of individuals having fewer contacts than the mean, and a significant minority having relatively very many…

物理与社会 · 物理学 2016-12-21 César Parra-Rojas , Thomas House , Alan J. McKane

Towards the end of an infectious disease outbreak, when a period has elapsed without new case notifications, a key question for public health policy makers is whether the outbreak can be declared over. This requires the benefits of a…

种群与进化 · 定量生物学 2025-08-22 M. J. Plank , W. S. Hart , J. Polonsky , M. Keita , S. Ahuka-Mundeke , R. N. Thompson

Epidemic dynamics in a stochastic network of interacting epidemic centers is considered. The epidemic and migration processes are modelled by Markov's chains. Explicit formulas for probability distribution of the migration process are…

种群与进化 · 定量生物学 2015-05-05 Igor Sazonov , Mark Kelbert

Epidemiological delays, such as incubation periods, serial intervals, and hospital lengths of stay, are among key quantities in infectious disease epidemiology that inform public health policy and clinical practice. This information is used…

There has been much recent interest in modelling epidemics on networks, particularly in the presence of substantial clustering. Here, we develop pairwise methods to answer questions that are often addressed using epidemic models, in…

种群与进化 · 定量生物学 2010-12-10 Thomas House , Matt J Keeling

This paper introduces a new optimal control model to describe and control the dynamics of infectious diseases. In the present model, the average time of isolation (i.e. hospitalization) of infectious population is the main time-dependent…

最优化与控制 · 数学 2015-05-06 Robin J. Evans , Musa Mammadov

Epidemic is a rapid and wide spread of infectious disease threatening many lives and economy damages. It is important to fore-tell the epidemic lifetime so to decide on timely and remedic actions. These measures include closing borders,…

We investigate the information-theoretical limits of inference tasks in epidemic spreading on graphs in the thermodynamic limit. The typical inference tasks consist in computing observables of the posterior distribution of the epidemic…

物理与社会 · 物理学 2023-12-25 Alfredo Braunstein , Louise Budzynski , Matteo Mariani

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

物理与社会 · 物理学 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

The importance of spatial networks in the spread of an epidemic is an essential aspect in modeling the dynamics of an infectious disease. Additionally, any realistic data-driven model must take into account the large uncertainty in the…

种群与进化 · 定量生物学 2022-01-17 Giulia Bertaglia , Lorenzo Pareschi

The non-equilibrium phase transition in models for epidemic spreading with long-range infections in combination with incubation times is investigated by field-theoretical and numerical methods. Here the spreading process is modelled by…

统计力学 · 物理学 2007-05-23 Julian Adamek , Michael Keller , Arne Senftleben , Haye Hinrichsen

Approximating the time to extinction of infection is an important problem in infection modelling. A variety of different approaches have been proposed in the literature. We study the performance of a number of such methods, and characterize…

概率论 · 数学 2017-07-11 Damian Clancy , Elliott Tjia

Health-policy planning requires evidence on the burden that epidemics place on healthcare systems. Multiple, often dependent, datasets provide a noisy and fragmented signal from the unobserved epidemic process including transmission and…

应用统计 · 统计学 2024-09-11 Alice Corbella , Anne M Presanis , Paul J Birrell , Daniela De Angelis

The spatial propagation of many livestock infectious diseases critically depends on the animal movements among premises; so the knowledge of movement data may help us to detect, manage and control an outbreak. The identification of robust…

种群与进化 · 定量生物学 2012-10-03 Paolo Bajardi , Alain Barrat , Lara Savini , Vittoria Colizza

Early detection of disease outbreaks is of paramount importance to implementing intervention strategies to mitigate the severity and duration of the outbreak. We build methodology that utilizes the characteristic profile of disease…

统计方法学 · 统计学 2012-01-20 Michael D. Porter , Jarad B. Niemi , Brian J. Reich