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相关论文: MOTOR: A Time-To-Event Foundation Model For Struct…

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Domain-specific foundation models for healthcare have expanded rapidly in recent years, yet foundation models for critical care time series remain relatively underexplored due to the limited size and availability of datasets. In this work,…

机器学习 · 计算机科学 2025-09-25 Katja Naasunnguaq Jagd , Rachael DeVries , Ole Winther

Foundation models (FMs) trained on electronic health records (EHRs) have shown strong performance on a range of clinical prediction tasks. However, adapting these models to local health systems remains challenging due to limited data…

Accurate prediction of the need for invasive mechanical ventilation (IMV) in intensive care units (ICUs) patients is crucial for timely interventions and resource allocation. However, variability in patient populations, clinical practices,…

机器学习 · 计算机科学 2026-01-28 Xiaolei Lu , Shamim Nemati

Deep learning for time series forecasting has seen significant advancements over the past decades. However, despite the success of large-scale pre-training in language and vision domains, pre-trained time series models remain limited in…

机器学习 · 计算机科学 2025-02-28 Xiaoming Shi , Shiyu Wang , Yuqi Nie , Dianqi Li , Zhou Ye , Qingsong Wen , Ming Jin

Machine learning (ML) models deployed in healthcare systems must face data drawn from continually evolving environments. However, researchers proposing such models typically evaluate them in a time-agnostic manner, splitting datasets…

机器学习 · 计算机科学 2023-07-21 Helen Zhou , Yuwen Chen , Zachary C. Lipton

Time is implicitly embedded in classification process: classifiers are usually built on existing data while to be applied on future data whose distributions (e.g., label and token) may change. However, existing state-of-the-art…

计算与语言 · 计算机科学 2025-02-14 Weisi Liu , Guangzeng Han , Xiaolei Huang

Irregular sampling of time series in electronic health records (EHRs) is one of the main challenges for developing machine learning models. Additionally, the pattern of missing data in certain clinical variables is not at random but depends…

机器学习 · 计算机科学 2024-06-17 Hojjat Karami , David Atienza , Anisoara Ionescu

Irregular time series, where data points are recorded at uneven intervals, are prevalent in healthcare settings, such as emergency wards where vital signs and laboratory results are captured at varying times. This variability, which…

机器学习 · 计算机科学 2024-10-16 Hrishikesh Patel , Ruihong Qiu , Adam Irwin , Shazia Sadiq , Sen Wang

Recent years have witnessed a growing interest for time series foundation models, with a strong emphasis on the forecasting task. Yet, the crucial task of out-of-domain imputation of missing values remains largely underexplored. We propose…

机器学习 · 计算机科学 2025-11-11 Etienne Le Naour , Tahar Nabil , Ghislain Agoua

Early prediction of patients at risk of clinical deterioration can help physicians intervene and alter their clinical course towards better outcomes. In addition to the accuracy requirement, early warning systems must make the predictions…

机器学习 · 计算机科学 2021-02-16 Ibrahim Hammoud , Prateek Prasanna , IV Ramakrishnan , Adam Singer , Mark Henry , Henry Thode

Time-to-event outcomes are commonly used as primary endpoints in randomized clinical trials. Despite this, relatively little work incorporates baseline covariate information while also accounting for stratified randomization, a common form…

统计方法学 · 统计学 2026-05-01 Raphael C. Kim , Brian Gilbert , Ramin Zabih , Michele Santacatterina , Ivan Diaz

Hospitals struggle to predict critical outcomes. Traditional early warning systems, like NEWS and MEWS, rely on static variables and fixed thresholds, limiting their adaptability, accuracy, and personalization. We previously developed the…

We address the problem of predicting when a disease will develop, i.e., medical event time (MET), from a patient's electronic health record (EHR). The MET of non-communicable diseases like diabetes is highly correlated to cumulative health…

机器学习 · 计算机科学 2023-06-01 Takayuki Katsuki , Kohei Miyaguchi , Akira Koseki , Toshiya Iwamori , Ryosuke Yanagiya , Atsushi Suzuki

Rich Electronic Health Records (EHR), have created opportunities to improve clinical processes using machine learning methods. Prediction of the same patient events at different time horizons can have very different applications and…

机器学习 · 计算机科学 2023-03-07 Hao Liu , Muhan Zhang , Zehao Dong , Lecheng Kong , Yixin Chen , Bradley Fritz , Dacheng Tao , Christopher King

In different areas of research, multiple recurrent competing risks (RCR) are often observed on the same observational unit. For instance, different types of cancer relapses are observed on the same patient and several types of component…

统计方法学 · 统计学 2020-10-27 Piaomu Liu

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

机器学习 · 计算机科学 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

The emergence of foundation models in healthcare has opened new avenues for learning generalizable representations from large scale clinical data. Yet, existing approaches often struggle to reconcile the tabular and event based nature of…

计算与语言 · 计算机科学 2025-10-17 Zhirong Chou , Quan Qin , Shi Li

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

机器学习 · 计算机科学 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei

Electronic health records (EHR) are irregular, asynchronous multivariate time series. As time-series foundation models increasingly tokenize events rather than discretizing time, the input layout becomes a key design choice. Grids expose…

机器学习 · 计算机科学 2026-03-13 Joohyung Lee , Kwanhyung Lee , Changhun Kim , Eunho Yang

The present study explores the interpretability of latent spaces produced by time series foundation models, focusing on their potential for visual analysis tasks. Specifically, we evaluate the MOMENT family of models, a set of…