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Accurate recurrence risk stratification is crucial for optimizing treatment plans for breast cancer patients. Current prognostic tools like Oncotype DX (ODX) offer valuable genomic insights for HR+/HER2- patients but are limited by cost and…

图像与视频处理 · 电气工程与系统科学 2024-09-25 Ziyu Su , Yongxin Guo , Robert Wesolowski , Gary Tozbikian , Nathaniel S. O'Connell , M. Khalid Khan Niazi , Metin N. Gurcan

Fault detection has a long tradition: the necessity to provide the most accurate diagnosis possible for a process plant criticality is somehow intrinsic in its functioning. Continuous monitoring is a possible way for early detection.…

系统与控制 · 电气工程与系统科学 2024-01-22 Martina Teruzzi , Nicola Demo , Gianluigi Rozza

Current cancer screening guidelines cover only a few cancer types and rely on narrowly defined criteria such as age or a single risk factor like smoking history, to identify high-risk individuals. Predictive models using electronic health…

Quantification learning is the task of predicting the label distribution of a set of instances. We study this problem in the context of graph-structured data, where the instances are vertices. Previously, this problem has only been…

机器学习 · 计算机科学 2026-01-01 Clemens Damke , Eyke Hüllermeier

Graph Anomaly Detection (GAD) is critical in security-sensitive domains, yet faces reliability challenges: miscalibrated confidence estimation (underconfidence in normal nodes, overconfidence in anomalies), adversarial vulnerability of…

机器学习 · 计算机科学 2025-04-04 Songran Bai , Xiaolong Zheng , Daniel Dajun Zeng

Large-scale multiple testing tasks often exhibit dependence, and leveraging the dependence between individual tests is still one challenging and important problem in statistics. With recent advances in graphical models, it is feasible to…

统计方法学 · 统计学 2012-10-19 Jie Liu , Chunming Zhang , Catherine McCarty , Peggy Peissig , Elizabeth Burnside , David Page

Among the challenges that the COVID-19 pandemic outbreak revealed is the problem to reduce the number of tests required for identifying the virus carriers in order to contain the viral spread while preserving the tests reliability. To cope…

信息论 · 计算机科学 2021-12-24 Catherine A. Haddad-Zaaknoon

Object detection has been dominated by anchor-based detectors for several years. Recently, anchor-free detectors have become popular due to the proposal of FPN and Focal Loss. In this paper, we first point out that the essential difference…

计算机视觉与模式识别 · 计算机科学 2020-06-23 Shifeng Zhang , Cheng Chi , Yongqiang Yao , Zhen Lei , Stan Z. Li

Respondent-driven sampling (RDS) is a widely used method for sampling from hard-to-reach human populations, especially groups most at-risk for HIV/AIDS. Data are collected through a peer-referral process in which current sample members…

统计方法学 · 统计学 2012-09-28 Krista J. Gile , Lisa G. Johnston , Matthew J. Salganik

Point cloud registration (PCR) is crucial for many downstream tasks, such as simultaneous localization and mapping (SLAM) and object tracking. This makes detecting and quantifying registration misalignment, i.e., PCR quality validation, an…

计算机视觉与模式识别 · 计算机科学 2026-02-09 Shipeng Liu , Ziliang Xiong , Khac-Hoang Ngo , Per-Erik Forssén

We intend to create a new risk assessment methodology that combines the best characteristics of both risk score and machine learning models. More specifically, we aim to develop a method that, besides having a good performance, offers a…

机器学习 · 计算机科学 2021-10-19 Francisco Valente , Jorge Henriques , Simão Paredes , Teresa Rocha , Paulo de Carvalho , João Morais

Time-to-event endpoints show an increasing popularity in phase II cancer trials. The standard statistical tool for such one-armed survival trials is the one-sample log-rank test. Its distributional properties are commonly derived in the…

统计方法学 · 统计学 2026-03-02 Moritz Fabian Danzer , Andreas Faldum , Rene Schmidt

Sparse representation based classification (SRC) methods have achieved remarkable results. SRC, however, still suffer from requiring enough training samples, insufficient use of test samples and instability of representation. In this paper,…

定量方法 · 定量生物学 2019-06-28 Xiao-Hui Yang , Li Tian , Yun-Mei Chen , Li-Jun Yang , Shuang Xu , Wen-Ming Wu

A key challenge in systems biology is the elucidation of the underlying principles, or fundamental laws, which determine the cellular phenotype. Understanding how these fundamental principles are altered in diseases like cancer is important…

分子网络 · 定量生物学 2014-08-06 Andrew Teschendorff , Peter Sollich , Reimer Kuehn

Retrieval-augmented generation (RAG) grounds large language models in external medical knowledge, yet standard retrievers frequently surface hard negatives that are semantically close to the query but describe clinically distinct…

信息检索 · 计算机科学 2026-04-07 Byeolhee Kim , Min-Kyung Kim , Young-Hak Kim , Tae-Joon Jeon

Anchor-based methods are a pivotal approach in handling clustering of large-scale data. However, these methods typically entail two distinct stages: selecting anchor points and constructing an anchor graph. This bifurcation, along with the…

机器学习 · 计算机科学 2024-10-31 Shikun Mei , Fangfang Li , Quanxue Gao , Ming Yang

We consider a network where an infection cascade has taken place and a subset of infected nodes has been partially observed. Our goal is to reconstruct the underlying cascade that is likely to have generated these observations. We reduce…

社会与信息网络 · 计算机科学 2018-11-21 Han Xiao , Cigdem Aslay , Aristides Gionis

Building phenotype models using electronic health record (EHR) data conventionally requires manually labeled cases and controls. Assigning labels is labor intensive and, for some phenotypes, identifying gold-standard controls is…

Population-based cancer registries depend on pathology reports as their primary diagnostic source, yet manual abstraction is resource-intensive and contributes to delays in cancer data. While transformer-based NLP systems have improved…

计算与语言 · 计算机科学 2026-01-05 Jonathan Simkin , Lovedeep Gondara , Zeeshan Rizvi , Gregory Doyle , Jeff Dowden , Dan Bond , Desmond Martin , Raymond Ng

Recently, some contrastive learning methods have been proposed to simultaneously learn representations and clustering assignments, achieving significant improvements. However, these methods do not take the category information and…

计算机视觉与模式识别 · 计算机科学 2021-04-06 Huasong Zhong , Jianlong Wu , Chong Chen , Jianqiang Huang , Minghua Deng , Liqiang Nie , Zhouchen Lin , Xian-Sheng Hua