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The RNA inverse folding problem aims to identify nucleotide sequences that preferentially adopt a given target secondary structure. While various heuristic and machine learning-based approaches have been proposed, many require a large…

机器学习 · 计算机科学 2026-02-19 Shuta Kikuchi , Shu Tanaka

Due to the importance of uncertainty quantification (UQ), Bayesian approach to inverse problems has recently gained popularity in applied mathematics, physics, and engineering. However, traditional Bayesian inference methods based on Markov…

统计计算 · 统计学 2022-04-26 Shiwei Lan , Shuyi Li , Babak Shahbaba

We consider optimal experimental design (OED) for Bayesian nonlinear inverse problems governed by partial differential equations (PDEs) under model uncertainty. Specifically, we consider inverse problems in which, in addition to the…

数值分析 · 数学 2024-07-03 Alen Alexanderian , Ruanui Nicholson , Noemi Petra

One of the main challenges for arbitrary-shaped text detection is to design a good text instance representation that allows networks to learn diverse text geometry variances. Most of existing methods model text instances in image spatial…

计算机视觉与模式识别 · 计算机科学 2021-04-23 Yiqin Zhu , Jianyong Chen , Lingyu Liang , Zhanghui Kuang , Lianwen Jin , Wayne Zhang

Diffeomorphic image registration (DIR) is a fundamental task in 3D medical image analysis that seeks topology-preserving deformations between image pairs. To ensure diffeomorphism, a common approach is to model the deformation field as the…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Mohammadjavad Matinkia , Nilanjan Ray

Data encoding is a common and central operation in most data analysis tasks. The performance of other models downstream in the computational process highly depends on the quality of data encoding. One of the most powerful ways to encode…

机器学习 · 计算机科学 2025-09-03 Teddy Lazebnik , Liron Simon-Keren

Experimental design is central to science and engineering. A ubiquitous challenge is how to maximize the value of information obtained from expensive or constrained experimental settings. Bayesian optimal experimental design (OED) provides…

统计方法学 · 统计学 2026-02-13 Sofia Mäkinen , Andrew B. Duncan , Tapio Helin

This work investigates in detail the performance and advantages of a new quantum Monte Carlo integrator, dubbed Quantum Fourier Iterative Amplitude Estimation (QFIAE), to numerically evaluate for the first time loop Feynman integrals in a…

高能物理 - 唯象学 · 物理学 2024-11-20 Jorge J. Martínez de Lejarza , Leandro Cieri , Michele Grossi , Sofia Vallecorsa , Germán Rodrigo

We introduce the novel class $(E_\alpha)_{\alpha \in [-\infty,1)}$ of reverse map projection embeddings, each one defining a unique new method of encoding classical data into quantum states. Inspired by well-known map projections from the…

量子物理 · 物理学 2024-08-20 Max Arnott , Dimitri Papaioannou , Kieran McDowall , Phalgun Lolur , Bambordé Baldé

Continuous-depth neural networks, such as Neural ODEs, have refashioned the understanding of residual neural networks in terms of non-linear vector-valued optimal control problems. The common solution is to use the adjoint sensitivity…

机器学习 · 计算机科学 2022-02-16 Andrew Corbett , Dmitry Kangin

The interior resonance problem of time domain integral equations (TDIEs) formulated to analyze acoustic field interactions on penetrable objects is investigated. Two types of TDIEs are considered: The first equation, which is termed the…

计算物理 · 物理学 2024-05-22 Rui Chen , Yifei Shi , Sadeed Bin Sayed , Mingyu Lu , Hakan Bagci

This study proposes median consensus embedding (MCE) to address variability in low-dimensional embeddings caused by random initialization in nonlinear dimensionality reduction techniques such as $t$-distributed stochastic neighbor…

机器学习 · 统计学 2025-12-10 Yui Tomo , Daisuke Yoneoka

A memetic framework for optimal inverse design is proposed by combining a local gradient-based procedure and a robust global scheme. The procedure is based on method-of-moments matrices and does not demand full inversion of a system matrix.…

最优化与控制 · 数学 2023-10-10 Miloslav Capek , Lukas Jelinek , Petr Kadlec , Mats Gustafsson

We present a reduced-order model (ROM) methodology for inverse scattering problems in which the reduced-order models are data-driven, i.e. they are constructed directly from data gathered by sensors. Moreover, the entries of the ROM contain…

数值分析 · 数学 2023-06-16 Jörn Zimmerling , Vladimir Druskin , Murthy Guddati , Elena Cherkaev , Rob Remis

Machine learning applied to computer vision and signal processing is achieving results comparable to the human brain on specific tasks due to the great improvements brought by the deep neural networks (DNN). The majority of state-of-the-art…

计算机视觉与模式识别 · 计算机科学 2020-06-30 José Augusto Stuchi , Levy Boccato , Romis Attux

Embedding static graphs in low-dimensional vector spaces plays a key role in network analytics and inference, supporting applications like node classification, link prediction, and graph visualization. However, many real-world networks…

机器学习 · 计算机科学 2021-07-23 Claudio D. T. Barros , Matheus R. F. Mendonça , Alex B. Vieira , Artur Ziviani

We present a new fixed mesh algorithm for solving a class of interface inverse problems for the typical elliptic interface problems. These interface inverse problems are formulated as shape optimization prob- lems whose objective…

数值分析 · 数学 2018-10-18 Ruchi Guo , Tao Lin , Yanping Lin

Inverse problems in partial differential equations (PDEs) involve estimating the physical parameters of a system from observed spatiotemporal solution fields. Neural networks are well-suited for PDE parameter estimation due to their…

机器学习 · 计算机科学 2026-05-27 Divyam Goel , Nithin Chalapathi , Sanjeev Raja , Aditi S. Krishnapriyan

The field of quantum computing has experienced a rapid expansion in recent years, with ongoing exploration of new technologies, a decrease in error rates, and a growth in the number of qubits available in quantum processors. However,…

量子物理 · 物理学 2023-03-16 Samuel Stein , Nathan Wiebe , Yufei Ding , James Ang , Ang Li

Graph embedding has become a key component of many data mining and analysis systems. Current graph embedding approaches either sample a large number of node pairs from a graph to learn node embeddings via stochastic optimization or…

社会与信息网络 · 计算机科学 2019-12-20 Artem Lutov , Dingqi Yang , Philippe Cudré-Mauroux