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Inferring treatment effects on a survival time outcome based on data from an observational study is challenging due to the presence of censoring and possible confounding. An additional challenge occurs when a unit's treatment affects the…

统计方法学 · 统计学 2025-08-13 Chanhwa Lee , Donglin Zeng , Michael Emch , John D. Clemens , Michael G. Hudgens

Feature screening is an important tool in analyzing ultrahigh-dimensional data, particularly in the field of Omics and oncology studies. However, most attention has been focused on identifying features that have a linear or monotonic impact…

统计方法学 · 统计学 2023-05-10 Yaxian Chen , KF Lam , Zhonghua Liu

In this paper, we mainly discuss the cure model with survival data. Different from the usual survival data with right-censoring, we incorporate the features of left-truncation and measurement error in covariates. Generally speaking,…

统计理论 · 数学 2019-01-01 Li-Pang Chen

A common concern when a policymaker draws causal inferences from and makes decisions based on observational data is that the measured covariates are insufficiently rich to account for all sources of confounding, i.e., the standard no…

统计方法学 · 统计学 2023-10-25 Tao Shen , Yifan Cui

In survival analysis, the lifetime under study is not always observed. In certain applications, for some individuals, the value of the lifetime is only known to be smaller or larger than some random duration. This framework represent an…

统计理论 · 数学 2020-02-25 Laurent Bordes , Maria Carmen Pardo , Christian Paroissin , Valentin Patilea

This paper proposes a modelling strategy to infer the impact of a covariate on the dependence structure of right-censored clustered event time data. The joint survival function of the event times is modelled using a parametric conditional…

统计方法学 · 统计学 2016-06-07 Candida Geerdens , Elif Fidan Acar , Paul Janssen

Assuming some regression model, it is common to study the conditional distribution of survival given covariates. Here, we consider the impact of further conditioning, specifically conditioning on a marginal survival function, known or…

应用统计 · 统计学 2016-10-11 Roxane Duroux , Cécile Chauvel , John O'Quigley

Balanced representation learning methods have been applied successfully to counterfactual inference from observational data. However, approaches that account for survival outcomes are relatively limited. Survival data are frequently…

This paper considers the problem of inferring the causal effect of a variable $Z$ on a dependently censored survival time $T$. We allow for unobserved confounding variables, such that the error term of the regression model for $T$ is…

统计理论 · 数学 2024-10-02 Gilles Crommen , Jad Beyhum , Ingrid Van Keilegom

Let P represent the source population with complete data, containing covariate $\mathbf{Z}$ and response $T$, and Q the target population, where only the covariate $\mathbf{Z}$ is available. We consider a setting with both label shift and…

统计方法学 · 统计学 2025-06-27 Yuxiang Zong , Yanyuan Ma , Ingrid Van Keilegom

Accurately predicting the time of occurrence of an event of interest is a critical problem in longitudinal data analysis. One of the main challenges in this context is the presence of instances whose event outcomes become unobservable after…

机器学习 · 计算机科学 2017-12-26 Ping Wang , Yan Li , Chandan K. Reddy

Skepticism about the assumption of no unmeasured confounding, also known as exchangeability, is often warranted in making causal inferences from observational data; because exchangeability hinges on an investigator's ability to accurately…

统计方法学 · 统计学 2023-02-22 Yifan Cui , Hongming Pu , Xu Shi , Wang Miao , Eric Tchetgen Tchetgen

We consider continuous-time survival or more general event-history settings, where the aim is to infer the causal effect of a time-dependent treatment process. This is formalised as the effect on the outcome event of a (possibly…

统计方法学 · 统计学 2024-04-23 Kjetil Røysland , Pål Ryalen , Mari Nygård , Vanessa Didelez

Interval-censored multi-state data arise in many studies of chronic diseases, where the health status of a subject can be characterized by a finite number of disease states and the transition between any two states is only known to occur…

统计方法学 · 统计学 2022-09-19 Yu Gu , Donglin Zeng , Gerardo Heiss , D. Y. Lin

Prevalent cohort sampling is commonly used to study the natural history of a disease when the disease is rare or it usually takes a long time to observe the failure event. It is known, however, that the collected sample in this situation is…

统计方法学 · 统计学 2022-09-05 Omidali Aghababaei Jazi

We propose a semiparametric framework for causal inference with right-censored survival outcomes and many weak invalid instruments, motivated by Mendelian randomization in biobank studies where classical methods may fail. We adopt an…

统计方法学 · 统计学 2025-10-06 Qiushi Bu , Wen Su , Xingqiu Zhao , Zhonghua Liu

We present a new estimator of the restricted mean survival time in randomized trials where there is right censoring that may depend on treatment and baseline variables. The proposed estimator leverages prognostic baseline variables to…

统计理论 · 数学 2016-08-22 Iván Díaz , Elizabeth Colantuoni , Daniel F. Hanley , Michael Rosenblum

In randomized trials and observational studies, it is often necessary to evaluate the extent to which an intervention affects a time-to-event outcome, which is only partially observed due to right censoring. For instance, in infectious…

统计方法学 · 统计学 2024-12-16 Yutong Jin , Peter B. Gilbert , Aaron Hudson

Learning causal effects of a binary exposure on time-to-event endpoints can be challenging because survival times may be partially observed due to censoring and systematically biased due to truncation. In this work, we present debiased…

统计方法学 · 统计学 2024-11-15 Eric R. Morenz , Charles J. Wolock , Marco Carone

Interval-censored data, in which the event time is only known to lie in some time interval, arise commonly in practice; for example, in a medical study in which patients visit clinics or hospitals at pre-scheduled times, and the events of…

统计方法学 · 统计学 2017-07-21 Wei Fu , Jeffrey S. Simonoff