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Treatment policy estimands are frequently favored by regulators, as they assess the effect of treatment assignment regardless of post-randomization events. Despite best efforts, missing data due to study discontinuation cannot be fully…

统计方法学 · 统计学 2026-05-13 Ajmal Oodally , Craig Wang , Zheng Li , Tim Morris , Tobias Mütze , Arunava Chakravartty

Stress testing poses a causal question: how would portfolio credit losses change if the macroeconomy followed an adverse counterfactual path? Yet standard practice remains predictive and might be therefore vulnerable to omitted-variable…

人工智能 · 计算机科学 2026-05-19 Yu Wang , Xiangchen Liu , Siguang Li

A standard assumption for causal inference from observational data is that one has measured a sufficiently rich set of covariates to ensure that within covariate strata, subjects are exchangeable across observed treatment values. Skepticism…

统计方法学 · 统计学 2020-09-24 Eric J Tchetgen Tchetgen , Andrew Ying , Yifan Cui , Xu Shi , Wang Miao

In medical and epidemiological studies, one of the most common settings is studying the effect of a treatment on a time-to-event outcome, where the time-to-event might be censored before end of study. A common parameter of interest in such…

统计方法学 · 统计学 2024-02-15 Guilherme W. F. Barros , Jenny Häggström

Cohort studies of the onset of a disease often encounter left-truncation on the event time of interest in addition to right-censoring due to variable enrollment times of study participants. Analysis of such event time data can be biased if…

统计方法学 · 统计学 2025-04-11 Spencer Matthews , Bin Nan

Sensitivity analysis is widely used to assess the robustness of causal conclusions in observational studies, yet its interaction with the structure of measured covariates is often overlooked. When latent confounders cannot be directly…

统计方法学 · 统计学 2026-02-17 Abhinandan Dalal , Iris Horng , Yang Feng , Dylan S. Small

Proximal causal inference (PCI) is a recently proposed framework to identify and estimate the causal effect of an exposure on an outcome in the presence of hidden confounders, using observed proxies. Specifically, PCI relies on two types of…

统计方法学 · 统计学 2025-07-29 Prabrisha Rakshit , Xu Shi , Eric Tchetgen Tchetgen

This report is designed to clarify a few points about the article "Semiparametric modeling of grouped current duration data with preferential reporting" by McLain, Sundaram, Thoma and Louis in Statistics in Medicine (McLain et al., 2014,…

应用统计 · 统计学 2018-01-03 Alexander C. McLain , Rajeshwari Sundaram , Marie Thoma , Germaine M. Buck Louis

We develop inference procedures for longitudinal data where some of the measurements are censored by fixed constants. We consider a semi-parametric quantile regression model that makes no distributional assumptions. Our research is…

统计理论 · 数学 2009-04-02 Huixia Judy Wang , Mendel Fygenson

We study causal inference for time-to-event outcomes under right censoring in the presence of unmeasured confounding. Focusing on structural accelerated failure time models, we develop an identification and inference framework that exploits…

统计方法学 · 统计学 2026-05-29 Qiushi Bu , Wen Su , Xinyu Zhang , Xingqiu Zhao , Zhonghua Liu

Simulation studies are useful for evaluating and developing statistical methods for the analyses of complex problems. Performance of methods may be affected by multiple complexities present in real scenarios. Generating sufficiently…

Structural failure time models are causal models for estimating the effect of time-varying treatments on a survival outcome. G-estimation and artificial censoring have been proposed to estimate the model parameters in the presence of…

统计方法学 · 统计学 2019-02-19 Shu Yang , Karen Pieper , Frank Cools

This paper provides a comprehensive analysis of variational inference in latent variable models for survival analysis, emphasizing the distinctive challenges associated with applying variational methods to survival data. We identify a…

机器学习 · 计算机科学 2025-06-05 Chuanhui Liu , Xiao Wang

Epidemiologic studies often evaluate the association between an exposure and an event risk. When time-varying, exposure updates usually occur at discrete visits although changes are in continuous time and survival models require values to…

In this paper, we are concerned with nonparametric estimation of the multivariate regression function in the presence of right censored data. More precisely, we propose a statistic that is shown to be asymptotically normally distributed…

统计理论 · 数学 2008-02-08 Mohammed Debbarh , Vivian Viallon

Databases derived from electronic health records (EHRs) are commonly subject to left truncation, a type of selection bias induced due to patients needing to survive long enough to satisfy certain entry criteria. Standard methods to adjust…

统计方法学 · 统计学 2022-03-01 Arjun Sondhi

In this paper the regression discontinuity design is adapted to the survival analysis setting with right-censored data, studied in an intensity based counting process framework. In particular, a local polynomial regression version of the…

统计方法学 · 统计学 2022-10-07 Emil Aas Stoltenberg

Density estimation is a classical problem in statistics and has received considerable attention when both the data has been fully observed and in the case of partially observed (censored) samples. In survival analysis or clinical trials, a…

应用统计 · 统计学 2018-04-18 German A. Schnaidt Grez , Brani Vidakovic

Survival analysis is a fundamental tool for modeling time-to-event data in healthcare, engineering, and finance, where censored observations pose significant challenges. While traditional methods like the Beran estimator offer nonparametric…

机器学习 · 计算机科学 2025-06-13 Andrei V. Konstantinov , Vlada A. Efremenko , Lev V. Utkin

Censored quantile regression has emerged as a prominent alternative to classical Cox's proportional hazards model or accelerated failure time model in both theoretical and applied statistics. While quantile regression has been extensively…

统计方法学 · 统计学 2024-08-27 Taehwa Choi , Seohyeon Park , Hunyong Cho , Sangbum Choi