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Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

组织与器官 · 定量生物学 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

With the number of fully-sequenced genomes now well over a hundred it has become possible to start investigating if there are any quantitative regularities in the genetic make-up of genomes. In (physics/0307001), I originally showed that…

基因组学 · 定量生物学 2007-05-23 Erik van Nimwegen

Numerous online services are data-driven: the behavior of users affects the system's parameters, and the system's parameters affect the users' experience of the service, which in turn affects the way users may interact with the system. For…

机器学习 · 计算机科学 2024-04-30 Sarah Dean , Mihaela Curmei , Lillian J. Ratliff , Jamie Morgenstern , Maryam Fazel

We extend the classical one-parameter Yule-Simon law to a version depending on two parameters, which in part appeared in Bertoin [2019] in the context of a preferential attachment algorithm with fading memory. By making the link to a…

概率论 · 数学 2020-01-07 Erich Baur , Jean Bertoin

Extensive research shows that more species-rich assemblages are generally more productive and efficient in resource use than comparable assemblages with fewer species. But the question of how diversity simultaneously affects the wide…

Neural scaling laws have become foundational for optimizing large language model (LLM) training, yet they typically assume a single dense model output. This limitation effectively overlooks "Familial models, a transformative paradigm…

机器学习 · 计算机科学 2026-01-26 Huan Song , Qingfei Zhao , Ting Long , Shuyu Tian , Hongjun An , Jiawei Shao , Xuelong Li

The processes taking place inside the living cell are now understood to the point where predictive computational models can be used to gain detailed understanding of important biological phenomena. A key challenge is to extrapolate this…

组织与器官 · 定量生物学 2018-10-26 Stefan Engblom Daniel B. Wilson , Ruth E. Baker

Superlinear scaling in cities, which appears in sociological quantities such as economic productivity and creative output relative to urban population size, has been observed but not been given a satisfactory theoretical explanation. Here…

物理与社会 · 物理学 2009-11-13 Samuel Arbesman , Jon M. Kleinberg , Steven H. Strogatz

Generalizable agents should adapt to diverse tasks and unseen environments beyond their training distribution. This position paper argues that such generalization requires environment scaling: expanding the distribution of executable…

人工智能 · 计算机科学 2026-05-19 Jiayi Zhang , Fanqi Kong , Guibin Zhang , Maojia Song , Zhaoyang Yu , Jianhao Ruan , Jinyu Xiang , Bang Liu , Chenglin Wu , Yuyu Luo

Key traits of unicellular species, like cell size, often follow scale-free or self-similar distributions, hinting at the possibility of an underlying critical process. However, linking such empirical scaling laws to the critical regime of…

种群与进化 · 定量生物学 2020-05-20 Jenny Held , Tom Lorimer , Francesco Pomati , Ruedi Stoop , Carlo Albert

Many processes and models --in biological, physical, social, and other contexts-- produce trees whose depth scales logarithmically with the number of leaves. Phylogenetic trees, describing the evolutionary relationships between biological…

Larger models learn tasks smaller models do not. What drives this phenomenon? We develop a simple phenomenological argument that power-law scaling already suggests that a larger model will be able to learn a part of the data distribution…

Many biological systems perform close to their physical limits, but promoting this optimality to a general principle seems to require implausibly fine tuning of parameters. Using examples from a wide range of systems, we show that this…

How can populations of learners develop coordinated, diverse behaviors without explicit communication or diversity incentives? We demonstrate that competition alone is sufficient to induce emergent specialization -- learners spontaneously…

机器学习 · 计算机科学 2026-01-29 Yuhao Li

Recent advances in large language models (LLMs) have been largely driven by scaling laws for individual models, which predict performance improvements as model parameters and data volume increase. However, the capabilities of any single LLM…

机器学习 · 计算机科学 2026-01-29 Dakuan Lu , Jiaqi Zhang , Cheng Yuan , Jiawei Shao , Xuelong Li

The growth function of populations is central in biomathematics. The main dogma is the existence of density dependence mechanisms, which can be modelled with distinct functional forms that depend on the size of the population. One important…

种群与进化 · 定量生物学 2010-10-15 Harold P. de Vladar

Analyses of urban scaling laws assume that observations in different cities are independent of the existence of nearby cities. Here we introduce generative models and data-analysis methods that overcome this limitation by modelling…

物理与社会 · 物理学 2021-01-21 Eduardo G. Altmann

Understanding how spatial configurations of economic activity emerge is important when formulating spatial planning and economic policy. A simple model was proposed by Simon, who assumed that firms grow at a rate proportional to their size,…

多智能体系统 · 计算机科学 2012-05-01 Jung-Hun Yang , Dick Ettema , Koen Frenken

In the Yule-Simon process, selection of words follows the preferential attachment mechanism, resulting in the power-law growth in the cumulative number of individual word occurrences. This is derived using mean-field approximation, assuming…

统计力学 · 物理学 2016-05-04 Yasuhiro Hashimoto

In discrete convex analysis, the scaling and proximity properties for the class of L$^\natural$-convex functions were established more than a decade ago and have been used to design efficient minimization algorithms. For the larger class of…

组合数学 · 数学 2017-12-13 Satoko Moriguchi , Kazuo Murota , Akihisa Tamura , Fabio Tardella